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A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer.

Dauch D, Rudalska R, Cossa G, Nault JC, Kang TW, Wuestefeld T, Hohmeyer A, Imbeaud S, Yevsa T, Hoenicke L, Pantsar T, Bozko P, Malek NP, Longerich T, Laufer S, Poso A, Zucman-Rossi J, Eilers M, Zender L.

Nat Med. 2016 Jul;22(7):744-53. doi: 10.1038/nm.4107. Epub 2016 May 23.


Evaluation of the medicinal herb Graptopetalum paraguayense as a treatment for liver cancer.

Hsu WH, Chang CC, Huang KW, Chen YC, Hsu SL, Wu LC, Tsou AP, Lai JM, Huang CY.

PLoS One. 2015 Apr 7;10(4):e0121298. doi: 10.1371/journal.pone.0121298. eCollection 2015.


Targeting aurora kinases with danusertib (PHA-739358) inhibits growth of liver metastases from gastroenteropancreatic neuroendocrine tumors in an orthotopic xenograft model.

Fraedrich K, Schrader J, Ittrich H, Keller G, Gontarewicz A, Matzat V, Kromminga A, Pace A, Moll J, Bläker M, Lohse AW, Hörsch D, Brümmendorf TH, Benten D.

Clin Cancer Res. 2012 Sep 1;18(17):4621-32. doi: 10.1158/1078-0432.CCR-11-2968. Epub 2012 Jul 2.


Overexpression and amplification of Aurora-A in hepatocellular carcinoma.

Jeng YM, Peng SY, Lin CY, Hsu HC.

Clin Cancer Res. 2004 Mar 15;10(6):2065-71.

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