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Items: 15


The origin of a primordial genome through spontaneous symmetry breaking.

Takeuchi N, Hogeweg P, Kaneko K.

Nat Commun. 2017 Aug 15;8(1):250. doi: 10.1038/s41467-017-00243-x.


Stronger selection can slow down evolution driven by recombination on a smooth fitness landscape.

Ueda M, Takeuchi N, Kaneko K.

PLoS One. 2017 Aug 15;12(8):e0183120. doi: 10.1371/journal.pone.0183120. eCollection 2017.


Evolutionarily stable disequilibrium: endless dynamics of evolution in a stationary population.

Takeuchi N, Kaneko K, Hogeweg P.

Proc Biol Sci. 2016 May 11;283(1830). pii: 20153109. doi: 10.1098/rspb.2015.3109.


Gene-specific selective sweeps in bacteria and archaea caused by negative frequency-dependent selection.

Takeuchi N, Cordero OX, Koonin EV, Kaneko K.

BMC Biol. 2015 Apr 16;13:20. doi: 10.1186/s12915-015-0131-7.


Horizontal gene transfer can rescue prokaryotes from Muller's ratchet: benefit of DNA from dead cells and population subdivision.

Takeuchi N, Kaneko K, Koonin EV.

G3 (Bethesda). 2014 Feb 19;4(2):325-39. doi: 10.1534/g3.113.009845.


Evolutionary dynamics of RNA-like replicator systems: A bioinformatic approach to the origin of life.

Takeuchi N, Hogeweg P.

Phys Life Rev. 2012 Sep;9(3):219-63. doi: 10.1016/j.plrev.2012.06.001. Epub 2012 Jun 13. Review.


Nature and intensity of selection pressure on CRISPR-associated genes.

Takeuchi N, Wolf YI, Makarova KS, Koonin EV.

J Bacteriol. 2012 Mar;194(5):1216-25. doi: 10.1128/JB.06521-11. Epub 2011 Dec 16.


On the origin of DNA genomes: evolution of the division of labor between template and catalyst in model replicator systems.

Takeuchi N, Hogeweg P, Koonin EV.

PLoS Comput Biol. 2011 Mar;7(3):e1002024. doi: 10.1371/journal.pcbi.1002024. Epub 2011 Mar 24.


Multilevel selection in models of prebiotic evolution II: a direct comparison of compartmentalization and spatial self-organization.

Takeuchi N, Hogeweg P.

PLoS Comput Biol. 2009 Oct;5(10):e1000542. doi: 10.1371/journal.pcbi.1000542. Epub 2009 Oct 16.


The evolution of strand preference in simulated RNA replicators with strand displacement: implications for the origin of transcription.

Takeuchi N, Salazar L, Poole AM, Hogeweg P.

Biol Direct. 2008 Aug 11;3:33. doi: 10.1186/1745-6150-3-33.


Evolution of complexity in RNA-like replicator systems.

Takeuchi N, Hogeweg P.

Biol Direct. 2008 Mar 27;3:11. doi: 10.1186/1745-6150-3-11.


The role of complex formation and deleterious mutations for the stability of RNA-like replicator systems.

Takeuchi N, Hogeweg P.

J Mol Evol. 2007 Dec;65(6):668-86. Epub 2007 Oct 23.


Error-threshold exists in fitness landscapes with lethal mutants.

Takeuchi N, Hogeweg P.

BMC Evol Biol. 2007 Feb 7;7:15; author reply 15.


Phenotypic error threshold; additivity and epistasis in RNA evolution.

Takeuchi N, Poorthuis PH, Hogeweg P.

BMC Evol Biol. 2005 Feb 3;5:9.


Multilevel selection in models of prebiotic evolution: compartments and spatial self-organization.

Hogeweg P, Takeuchi N.

Orig Life Evol Biosph. 2003 Oct;33(4-5):375-403. Review.


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