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Maestro endothelium conducts the neutrophils.

Grieshaber-Bouyer R, Nigrovic PA.

Blood. 2018 Oct 25;132(17):1734-1735. doi: 10.1182/blood-2018-09-872085. No abstract available.


Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes.

Westra HJ, Martínez-Bonet M, Onengut-Gumuscu S, Lee A, Luo Y, Teslovich N, Worthington J, Martin J, Huizinga T, Klareskog L, Rantapaa-Dahlqvist S, Chen WM, Quinlan A, Todd JA, Eyre S, Nigrovic PA, Gregersen PK, Rich SS, Raychaudhuri S.

Nat Genet. 2018 Oct;50(10):1366-1374. doi: 10.1038/s41588-018-0216-7. Epub 2018 Sep 17.


High-throughput identification of noncoding functional SNPs via type IIS enzyme restriction.

Li G, Martínez-Bonet M, Wu D, Yang Y, Cui J, Nguyen HN, Cunin P, Levescot A, Bai M, Westra HJ, Okada Y, Brenner MB, Raychaudhuri S, Hendrickson EA, Maas RL, Nigrovic PA.

Nat Genet. 2018 Aug;50(8):1180-1188. doi: 10.1038/s41588-018-0159-z. Epub 2018 Jul 16.


Disrupted N-linked glycosylation as a disease mechanism in deficiency of ADA2.

Lee PY, Huang Y, Zhou Q, Schnappauf O, Hershfield MS, Li Y, Ganson NJ, Sampaio Moura N, Delmonte OM, Stone SS, Rivkin MJ, Pai SY, Lyons T, Sundel RP, Hsu VW, Notarangelo LD, Aksentijevich I, Nigrovic PA.

J Allergy Clin Immunol. 2018 Oct;142(4):1363-1365.e8. doi: 10.1016/j.jaci.2018.05.038. Epub 2018 Jun 21. No abstract available.


Hip Synovial Fluid Cell Counts in Children From a Lyme Disease Endemic Area.

Dart AH, Michelson KA, Aronson PL, Garro AC, Lee TJ, Glerum KM, Nigrovic PA, Kocher MS, Bachur RG, Nigrovic LE.

Pediatrics. 2018 May;141(5). pii: e20173810. doi: 10.1542/peds.2017-3810. Epub 2018 Apr 18.


Editorial: Toward Personalized Treatment for Systemic Juvenile Idiopathic Arthritis.

Vastert SJ, Nigrovic PA.

Arthritis Rheumatol. 2018 Aug;70(8):1172-1174. doi: 10.1002/art.40501. Epub 2018 Jun 29. No abstract available.


Bayesian comparative effectiveness study of four consensus treatment plans for initial management of systemic juvenile idiopathic arthritis: FiRst-Line Options for Systemic juvenile idiopathic arthritis Treatment (FROST).

Nigrovic PA, Beukelman T, Tomlinson G, Feldman BM, Schanberg LE, Kimura Y; Childhood Arthritis and Rheumatology Research Alliance Systemic Juvenile Idiopathic Arthritis Consensus Treatment Plan Workgroup.

Clin Trials. 2018 Jun;15(3):268-277. doi: 10.1177/1740774518761367. Epub 2018 Mar 15.


Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis.

Mizoguchi F, Slowikowski K, Wei K, Marshall JL, Rao DA, Chang SK, Nguyen HN, Noss EH, Turner JD, Earp BE, Blazar PE, Wright J, Simmons BP, Donlin LT, Kalliolias GD, Goodman SM, Bykerk VP, Ivashkiv LB, Lederer JA, Hacohen N, Nigrovic PA, Filer A, Buckley CD, Raychaudhuri S, Brenner MB.

Nat Commun. 2018 Feb 23;9(1):789. doi: 10.1038/s41467-018-02892-y.


Age and fecal microbial strain-specific differences in patients with spondyloarthritis.

Stoll ML, Weiss PF, Weiss JE, Nigrovic PA, Edelheit BS, Bridges SL Jr, Danila MI, Spencer CH, Punaro MG, Schikler K, Reiff A, Kumar R, Cron RQ, Morrow CD, Lefkowitz EJ.

Arthritis Res Ther. 2018 Jan 30;20(1):14. doi: 10.1186/s13075-018-1510-6.


The Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans: Toward Comparative Effectiveness in the Pediatric Rheumatic Diseases.

Ringold S, Nigrovic PA, Feldman BM, Tomlinson GA, von Scheven E, Wallace CA, Huber AM, Schanberg LE, Li SC, Weiss PF, Fuhlbrigge RC, Morgan EM, Kimura Y.

Arthritis Rheumatol. 2018 May;70(5):669-678. doi: 10.1002/art.40395. Epub 2018 Mar 31.


Mycobacterial infection induces higher interleukin-1β and dysregulated lung inflammation in mice with defective leukocyte NADPH oxidase.

Chao WC, Yen CL, Hsieh CY, Huang YF, Tseng YL, Nigrovic PA, Shieh CC.

PLoS One. 2017 Dec 11;12(12):e0189453. doi: 10.1371/journal.pone.0189453. eCollection 2017.


Review: Genetics and the Classification of Arthritis in Adults and Children.

Nigrovic PA, Raychaudhuri S, Thompson SD.

Arthritis Rheumatol. 2018 Jan;70(1):7-17. doi: 10.1002/art.40350. Epub 2017 Dec 1. Review.


High-throughput characterization of the functional impact of IgG Fc glycan aberrancy in juvenile idiopathic arthritis.

Cheng HD, Stöckmann H, Adamczyk B, McManus CA, Ercan A, Holm IA, Rudd PM, Ackerman ME, Nigrovic PA.

Glycobiology. 2017 Dec 1;27(12):1099-1108. doi: 10.1093/glycob/cwx082.


CD177 modulates human neutrophil migration through activation-mediated integrin and chemoreceptor regulation.

Bai M, Grieshaber-Bouyer R, Wang J, Schmider AB, Wilson ZS, Zeng L, Halyabar O, Godin MD, Nguyen HN, Levescot A, Cunin P, Lefort CT, Soberman RJ, Nigrovic PA.

Blood. 2017 Nov 9;130(19):2092-2100. doi: 10.1182/blood-2017-03-768507. Epub 2017 Aug 14.


The metabolic regulator mTORC1 controls terminal myeloid differentiation.

Lee PY, Sykes DB, Ameri S, Kalaitzidis D, Charles JF, Nelson-Maney N, Wei K, Cunin P, Morris A, Cardona AE, Root DE, Scadden DT, Nigrovic PA.

Sci Immunol. 2017 May 26;2(11). pii: eaam6641. doi: 10.1126/sciimmunol.aam6641.


Genome-Wide Association Meta-Analysis Reveals Novel Juvenile Idiopathic Arthritis Susceptibility Loci.

McIntosh LA, Marion MC, Sudman M, Comeau ME, Becker ML, Bohnsack JF, Fingerlin TE, Griffin TA, Haas JP, Lovell DJ, Maier LA, Nigrovic PA, Prahalad S, Punaro M, Rosé CD, Wallace CA, Wise CA, Moncrieffe H, Howard TD, Langefeld CD, Thompson SD.

Arthritis Rheumatol. 2017 Nov;69(11):2222-2232. doi: 10.1002/art.40216. Epub 2017 Oct 12.


Transcriptional profiles of JIA patient blood with subsequent poor response to methotrexate.

Moncrieffe H, Bennett MF, Tsoras M, Luyrink LK, Johnson AL, Xu H, Dare J, Becker ML, Prahalad S, Rosenkranz M, O'Neil KM, Nigrovic PA, Griffin TA, Lovell DJ, Grom AA, Medvedovic M, Thompson SD.

Rheumatology (Oxford). 2017 Sep 1;56(9):1542-1551. doi: 10.1093/rheumatology/kex206.


Barriers and Facilitators of Mentoring for Trainees and Early Career Investigators in Rheumatology Research: Current State, Identification of Needs, and Road Map to an Inter-Institutional Adult Rheumatology Mentoring Program.

Ogdie A, Sparks JA, Angeles-Han ST, Bush K, Castelino FV, Golding A, Jiang Y, Kahlenberg JM, Kim AHJ, Lee YC, Machireddy K, Ombrello MJ, Shah AA, Wallace ZS, Nigrovic PA, Makris UE; American College of Rheumatology Early Career Investigator Subcommittee of the Committee on Research.

Arthritis Care Res (Hoboken). 2018 Mar;70(3):445-453. doi: 10.1002/acr.23286. Epub 2018 Feb 6.


Effect of Biologic Therapy on Clinical and Laboratory Features of Macrophage Activation Syndrome Associated With Systemic Juvenile Idiopathic Arthritis.

Schulert GS, Minoia F, Bohnsack J, Cron RQ, Hashad S, KonÉ-Paut I, Kostik M, Lovell D, Maritsi D, Nigrovic PA, Pal P, Ravelli A, Shimizu M, Stanevicha V, Vastert S, Woerner A, de Benedetti F, Grom AA.

Arthritis Care Res (Hoboken). 2018 Mar;70(3):409-419. doi: 10.1002/acr.23277. Epub 2018 Jan 30.


Pilot study comparing the Childhood Arthritis & Rheumatology Research Alliance (CARRA) systemic Juvenile Idiopathic Arthritis Consensus Treatment Plans.

Kimura Y, Grevich S, Beukelman T, Morgan E, Nigrovic PA, Mieszkalski K, Graham TB, Ibarra M, Ilowite N, Klein-Gitelman M, Onel K, Prahalad S, Punaro M, Ringold S, Toib D, Van Mater H, Weiss JE, Weiss PF, Schanberg LE; CARRA Registry Investigators.

Pediatr Rheumatol Online J. 2017 Apr 11;15(1):23. doi: 10.1186/s12969-017-0157-1.

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