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Items: 20

1.

Phenotype onset in Huntington's disease knock-in mice is correlated with the incomplete splicing of the mutant huntingtin gene.

Franich NR, Hickey MA, Zhu C, Osborne GF, Ali N, Chu T, Bove NH, Lemesre V, Lerner RP, Zeitlin SO, Howland D, Neueder A, Landles C, Bates GP, Chesselet MF.

J Neurosci Res. 2019 Jul 7. doi: 10.1002/jnr.24493. [Epub ahead of print]

PMID:
31282030
2.

RNA-Mediated Disease Mechanisms in Neurodegenerative Disorders.

Neueder A.

J Mol Biol. 2019 Apr 19;431(9):1780-1791. doi: 10.1016/j.jmb.2018.12.012. Epub 2018 Dec 29. Review.

PMID:
30597161
3.

Regulatory mechanisms of incomplete huntingtin mRNA splicing.

Neueder A, Dumas AA, Benjamin AC, Bates GP.

Nat Commun. 2018 Sep 27;9(1):3955. doi: 10.1038/s41467-018-06281-3.

4.

RNA Related Pathology in Huntington's Disease.

Neueder A, Bates GP.

Adv Exp Med Biol. 2018;1049:85-101. doi: 10.1007/978-3-319-71779-1_4. Review.

PMID:
29427099
5.

Myostatin inhibition prevents skeletal muscle pathophysiology in Huntington's disease mice.

Bondulich MK, Jolinon N, Osborne GF, Smith EJ, Rattray I, Neueder A, Sathasivam K, Ahmed M, Ali N, Benjamin AC, Chang X, Dick JRT, Ellis M, Franklin SA, Goodwin D, Inuabasi L, Lazell H, Lehar A, Richard-Londt A, Rosinski J, Smith DL, Wood T, Tabrizi SJ, Brandner S, Greensmith L, Howland D, Munoz-Sanjuan I, Lee SJ, Bates GP.

Sci Rep. 2017 Oct 27;7(1):14275. doi: 10.1038/s41598-017-14290-3.

6.

HSF1-dependent and -independent regulation of the mammalian in vivo heat shock response and its impairment in Huntington's disease mouse models.

Neueder A, Gipson TA, Batterton S, Lazell HJ, Farshim PP, Paganetti P, Housman DE, Bates GP.

Sci Rep. 2017 Oct 2;7(1):12556. doi: 10.1038/s41598-017-12897-0.

7.

The pathogenic exon 1 HTT protein is produced by incomplete splicing in Huntington's disease patients.

Neueder A, Landles C, Ghosh R, Howland D, Myers RH, Faull RLM, Tabrizi SJ, Bates GP.

Sci Rep. 2017 May 2;7(1):1307. doi: 10.1038/s41598-017-01510-z.

8.

Cre recombinase expression or topical tamoxifen treatment do not affect retinal structure and function, neuronal vulnerability or glial reactivity in the mouse eye.

Boneva SK, Groß TR, Schlecht A, Schmitt SI, Sippl C, Jägle H, Volz C, Neueder A, Tamm ER, Braunger BM.

Neuroscience. 2016 Jun 14;325:188-201. doi: 10.1016/j.neuroscience.2016.03.050. Epub 2016 Mar 26.

PMID:
27026593
9.

Three Huntington's Disease Specific Mutation-Carrying Human Embryonic Stem Cell Lines Have Stable Number of CAG Repeats upon In Vitro Differentiation into Cardiomyocytes.

Jacquet L, Neueder A, Földes G, Karagiannis P, Hobbs C, Jolinon N, Mioulane M, Sakai T, Harding SE, Ilic D.

PLoS One. 2015 May 20;10(5):e0126860. doi: 10.1371/journal.pone.0126860. eCollection 2015.

10.

A common gene expression signature in Huntington's disease patient brain regions.

Neueder A, Bates GP.

BMC Med Genomics. 2014 Oct 30;7:60. doi: 10.1186/s12920-014-0060-2.

11.

Dysfunction of the CNS-heart axis in mouse models of Huntington's disease.

Mielcarek M, Inuabasi L, Bondulich MK, Muller T, Osborne GF, Franklin SA, Smith DL, Neueder A, Rosinski J, Rattray I, Protti A, Bates GP.

PLoS Genet. 2014 Aug 7;10(8):e1004550. doi: 10.1371/journal.pgen.1004550. eCollection 2014 Aug.

12.

Novel isoforms of heat shock transcription factor 1, HSF1γα and HSF1γβ, regulate chaperone protein gene transcription.

Neueder A, Achilli F, Moussaoui S, Bates GP.

J Biol Chem. 2014 Jul 18;289(29):19894-906. doi: 10.1074/jbc.M114.570739. Epub 2014 May 22.

13.

Contesting the dogma of an age-related heat shock response impairment: implications for cardiac-specific age-related disorders.

Carnemolla A, Labbadia JP, Lazell H, Neueder A, Moussaoui S, Bates GP.

Hum Mol Genet. 2014 Jul 15;23(14):3641-56. doi: 10.1093/hmg/ddu073. Epub 2014 Feb 19.

14.

Aberrantly spliced HTT, a new player in Huntington's disease pathogenesis.

Gipson TA, Neueder A, Wexler NS, Bates GP, Housman D.

RNA Biol. 2013 Nov;10(11):1647-52. doi: 10.4161/rna.26706. Epub 2013 Oct 11.

15.

Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease.

Sathasivam K, Neueder A, Gipson TA, Landles C, Benjamin AC, Bondulich MK, Smith DL, Faull RL, Roos RA, Howland D, Detloff PJ, Housman DE, Bates GP.

Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2366-70. doi: 10.1073/pnas.1221891110. Epub 2013 Jan 22.

16.

Small ribosomal protein RPS0 stimulates translation initiation by mediating 40S-binding of eIF3 via its direct contact with the eIF3a/TIF32 subunit.

Kouba T, Dányi I, Gunišová S, Munzarová V, Vlčková V, Cuchalová L, Neueder A, Milkereit P, Valášek LS.

PLoS One. 2012;7(7):e40464. doi: 10.1371/journal.pone.0040464. Epub 2012 Jul 5.

17.

Interrelationships between yeast ribosomal protein assembly events and transient ribosome biogenesis factors interactions in early pre-ribosomes.

Jakob S, Ohmayer U, Neueder A, Hierlmeier T, Perez-Fernandez J, Hochmuth E, Deutzmann R, Griesenbeck J, Tschochner H, Milkereit P.

PLoS One. 2012;7(3):e32552. doi: 10.1371/journal.pone.0032552. Epub 2012 Mar 14.

18.

A local role for the small ribosomal subunit primary binder rpS5 in final 18S rRNA processing in yeast.

Neueder A, Jakob S, Pöll G, Linnemann J, Deutzmann R, Tschochner H, Milkereit P.

PLoS One. 2010 Apr 19;5(4):e10194. doi: 10.1371/journal.pone.0010194.

19.

rRNA maturation in yeast cells depleted of large ribosomal subunit proteins.

Pöll G, Braun T, Jakovljevic J, Neueder A, Jakob S, Woolford JL Jr, Tschochner H, Milkereit P.

PLoS One. 2009 Dec 11;4(12):e8249. doi: 10.1371/journal.pone.0008249.

20.

Analysis of the in vivo assembly pathway of eukaryotic 40S ribosomal proteins.

Ferreira-Cerca S, Pöll G, Kühn H, Neueder A, Jakob S, Tschochner H, Milkereit P.

Mol Cell. 2007 Nov 9;28(3):446-57.

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