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Expansion in CD39⁺ CD4⁺ immunoregulatory t cells and rarity of Th17 cells in HTLV-1 infected patients is associated with neurological complications.
Leal FE, Ndhlovu LC, Hasenkrug AM, Bruno FR, Carvalho KI, Wynn-Williams H, Neto WK, Sanabani SS, Segurado AC, Nixon DF, Kallas EG. Leal FE, et al. Among authors: neto wk. PLoS Negl Trop Dis. 2013;7(2):e2028. doi: 10.1371/journal.pntd.0002028. Epub 2013 Feb 7. PLoS Negl Trop Dis. 2013. PMID: 23409198 Free PMC article.
The frequency of CD127low expressing CD4+CD25high T regulatory cells is inversely correlated with human T lymphotrophic virus type-1 (HTLV-1) proviral load in HTLV-1-infection and HTLV-1-associated myelopathy/tropical spastic paraparesis.
Michaëlsson J, Barbosa HM, Jordan KA, Chapman JM, Brunialti MK, Neto WK, Nukui Y, Sabino EC, Chieia MA, Oliveira AS, Nixon DF, Kallas EG. Michaëlsson J, et al. Among authors: neto wk. BMC Immunol. 2008 Jul 29;9:41. doi: 10.1186/1471-2172-9-41. BMC Immunol. 2008. PMID: 18664281 Free PMC article.
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