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Items: 18

1.

Molecular analyses of neurogenic defects in a human pluripotent stem cell model of fragile X syndrome.

Boland MJ, Nazor KL, Tran HT, Szücs A, Lynch CL, Paredes R, Tassone F, Sanna PP, Hagerman RJ, Loring JF.

Brain. 2017 Mar 1;140(3):582-598. doi: 10.1093/brain/aww357.

2.

Mission critical: the need for proteomics in the era of next-generation sequencing and precision medicine.

Cayer DM, Nazor KL, Schork NJ.

Hum Mol Genet. 2016 Oct 1;25(R2):R182-R189. Epub 2016 Jul 20. Review.

PMID:
27439388
3.

Whole-genome mutational burden analysis of three pluripotency induction methods.

Bhutani K, Nazor KL, Williams R, Tran H, Dai H, Džakula Ž, Cho EH, Pang AW, Rao M, Cao H, Schork NJ, Loring JF.

Nat Commun. 2016 Feb 19;7:10536. doi: 10.1038/ncomms10536.

4.

Human stem cells from single blastomeres reveal pathways of embryonic or trophoblast fate specification.

Zdravkovic T, Nazor KL, Larocque N, Gormley M, Donne M, Hunkapillar N, Giritharan G, Bernstein HS, Wei G, Hebrok M, Zeng X, Genbacev O, Mattis A, McMaster MT, Krtolica A, Valbuena D, Simón C, Laurent LC, Loring JF, Fisher SJ.

Development. 2015 Dec 1;142(23):4010-25. doi: 10.1242/dev.122846. Epub 2015 Oct 19.

5.

DNA methylation fingerprint of neuroblastoma reveals new biological and clinical insights.

Gómez S, Castellano G, Mayol G, Suñol M, Queiros A, Bibikova M, Nazor KL, Loring JF, Lemos I, Rodríguez E, de Torres C, Mora J, Martín-Subero JI, Lavarino C.

Epigenomics. 2015 Oct;7(7):1137-53. doi: 10.2217/epi.15.49. Epub 2015 Jun 12.

6.

Dynamic changes in replication timing and gene expression during lineage specification of human pluripotent stem cells.

Rivera-Mulia JC, Buckley Q, Sasaki T, Zimmerman J, Didier RA, Nazor K, Loring JF, Lian Z, Weissman S, Robins AJ, Schulz TC, Menendez L, Kulik MJ, Dalton S, Gabr H, Kahveci T, Gilbert DM.

Genome Res. 2015 Aug;25(8):1091-103. doi: 10.1101/gr.187989.114. Epub 2015 Jun 8.

7.

Increased risk of genetic and epigenetic instability in human embryonic stem cells associated with specific culture conditions.

Garitaonandia I, Amir H, Boscolo FS, Wambua GK, Schultheisz HL, Sabatini K, Morey R, Waltz S, Wang YC, Tran H, Leonardo TR, Nazor K, Slavin I, Lynch C, Li Y, Coleman R, Gallego Romero I, Altun G, Reynolds D, Dalton S, Parast M, Loring JF, Laurent LC.

PLoS One. 2015 Feb 25;10(2):e0118307. doi: 10.1371/journal.pone.0118307. eCollection 2015.

8.

Application of a low cost array-based technique - TAB-Array - for quantifying and mapping both 5mC and 5hmC at single base resolution in human pluripotent stem cells.

Nazor KL, Boland MJ, Bibikova M, Klotzle B, Yu M, Glenn-Pratola VL, Schell JP, Coleman RL, Cabral-da-Silva MC, Schmidt U, Peterson SE, He C, Loring JF, Fan JB.

Genomics. 2014 Nov;104(5):358-67. doi: 10.1016/j.ygeno.2014.08.014. Epub 2014 Aug 29.

9.

Epigenetic therapy for Friedreich ataxia.

Soragni E, Miao W, Iudicello M, Jacoby D, De Mercanti S, Clerico M, Longo F, Piga A, Ku S, Campau E, Du J, Penalver P, Rai M, Madara JC, Nazor K, O'Connor M, Maximov A, Loring JF, Pandolfo M, Durelli L, Gottesfeld JM, Rusche JR.

Ann Neurol. 2014 Oct;76(4):489-508. doi: 10.1002/ana.24260. Epub 2014 Sep 16.

10.

Epigenetic regulation of pluripotency and differentiation.

Boland MJ, Nazor KL, Loring JF.

Circ Res. 2014 Jul 7;115(2):311-24. doi: 10.1161/CIRCRESAHA.115.301517. Review.

11.

BMP4-directed trophoblast differentiation of human embryonic stem cells is mediated through a ΔNp63+ cytotrophoblast stem cell state.

Li Y, Moretto-Zita M, Soncin F, Wakeland A, Wolfe L, Leon-Garcia S, Pandian R, Pizzo D, Cui L, Nazor K, Loring JF, Crum CP, Laurent LC, Parast MM.

Development. 2013 Oct;140(19):3965-76. doi: 10.1242/dev.092155. Epub 2013 Sep 4.

12.

Matched miRNA and mRNA signatures from an hESC-based in vitro model of pancreatic differentiation reveal novel regulatory interactions.

Liao X, Xue H, Wang YC, Nazor KL, Guo S, Trivedi N, Peterson SE, Liu Y, Loring JF, Laurent LC.

J Cell Sci. 2013 Sep 1;126(Pt 17):3848-61. doi: 10.1242/jcs.123570. Epub 2013 Jun 26.

13.

Generation of mice derived from induced pluripotent stem cells.

Boland MJ, Hazen JL, Nazor KL, Rodriguez AR, Martin G, Kupriyanov S, Baldwin KK.

J Vis Exp. 2012 Nov 29;(69):e4003. doi: 10.3791/4003.

14.

Equally potent? Does cellular reprogramming justify the abandonment of human embryonic stem cells?

Nazor KL, Loring JF, Laurent LC.

EMBO Rep. 2012 Oct;13(10):890-4. doi: 10.1038/embor.2012.134. Epub 2012 Sep 18. No abstract available.

15.

Recurrent variations in DNA methylation in human pluripotent stem cells and their differentiated derivatives.

Nazor KL, Altun G, Lynch C, Tran H, Harness JV, Slavin I, Garitaonandia I, Müller FJ, Wang YC, Boscolo FS, Fakunle E, Dumevska B, Lee S, Park HS, Olee T, D'Lima DD, Semechkin R, Parast MM, Galat V, Laslett AL, Schmidt U, Keirstead HS, Loring JF, Laurent LC.

Cell Stem Cell. 2012 May 4;10(5):620-34. doi: 10.1016/j.stem.2012.02.013.

16.

Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells.

Israel MA, Yuan SH, Bardy C, Reyna SM, Mu Y, Herrera C, Hefferan MP, Van Gorp S, Nazor KL, Boscolo FS, Carson CT, Laurent LC, Marsala M, Gage FH, Remes AM, Koo EH, Goldstein LS.

Nature. 2012 Jan 25;482(7384):216-20. doi: 10.1038/nature10821.

17.

Specific lectin biomarkers for isolation of human pluripotent stem cells identified through array-based glycomic analysis.

Wang YC, Nakagawa M, Garitaonandia I, Slavin I, Altun G, Lacharite RM, Nazor KL, Tran HT, Lynch CL, Leonardo TR, Liu Y, Peterson SE, Laurent LC, Yamanaka S, Loring JF.

Cell Res. 2011 Nov;21(11):1551-63. doi: 10.1038/cr.2011.148. Epub 2011 Sep 6.

18.

Adult mice generated from induced pluripotent stem cells.

Boland MJ, Hazen JL, Nazor KL, Rodriguez AR, Gifford W, Martin G, Kupriyanov S, Baldwin KK.

Nature. 2009 Sep 3;461(7260):91-4. doi: 10.1038/nature08310.

PMID:
19672243

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