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Year Number of Results
1998 2
1999 4
2000 3
2001 6
2003 1
2004 1
2006 1
2011 2
2012 3
2013 3
2014 1
2016 3
2017 1
2018 3
2019 5
2020 4
2021 6
2022 6
2023 5
2024 3

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58 results

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Page 1
4'-Fluorouridine is an oral antiviral that blocks respiratory syncytial virus and SARS-CoV-2 replication.
Sourimant J, Lieber CM, Aggarwal M, Cox RM, Wolf JD, Yoon JJ, Toots M, Ye C, Sticher Z, Kolykhalov AA, Martinez-Sobrido L, Bluemling GR, Natchus MG, Painter GR, Plemper RK. Sourimant J, et al. Among authors: natchus mg. Science. 2022 Jan 14;375(6577):161-167. doi: 10.1126/science.abj5508. Epub 2021 Dec 2. Science. 2022. PMID: 34855509 Free PMC article.
An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.
Sheahan TP, Sims AC, Zhou S, Graham RL, Pruijssers AJ, Agostini ML, Leist SR, Schäfer A, Dinnon KH 3rd, Stevens LJ, Chappell JD, Lu X, Hughes TM, George AS, Hill CS, Montgomery SA, Brown AJ, Bluemling GR, Natchus MG, Saindane M, Kolykhalov AA, Painter G, Harcourt J, Tamin A, Thornburg NJ, Swanstrom R, Denison MR, Baric RS. Sheahan TP, et al. Among authors: natchus mg. Sci Transl Med. 2020 Apr 29;12(541):eabb5883. doi: 10.1126/scitranslmed.abb5883. Epub 2020 Apr 6. Sci Transl Med. 2020. PMID: 32253226 Free PMC article.
4'-Fluorouridine mitigates lethal infection with pandemic human and highly pathogenic avian influenza viruses.
Lieber CM, Aggarwal M, Yoon JJ, Cox RM, Kang HJ, Sourimant J, Toots M, Johnson SK, Jones CA, Sticher ZM, Kolykhalov AA, Saindane MT, Tompkins SM, Planz O, Painter GR, Natchus MG, Sakamoto K, Plemper RK. Lieber CM, et al. Among authors: natchus mg. PLoS Pathog. 2023 Apr 17;19(4):e1011342. doi: 10.1371/journal.ppat.1011342. eCollection 2023 Apr. PLoS Pathog. 2023. PMID: 37068076 Free PMC article.
SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801.
Wahl A, Gralinski LE, Johnson CE, Yao W, Kovarova M, Dinnon KH 3rd, Liu H, Madden VJ, Krzystek HM, De C, White KK, Gully K, Schäfer A, Zaman T, Leist SR, Grant PO, Bluemling GR, Kolykhalov AA, Natchus MG, Askin FB, Painter G, Browne EP, Jones CD, Pickles RJ, Baric RS, Garcia JV. Wahl A, et al. Among authors: natchus mg. Nature. 2021 Mar;591(7850):451-457. doi: 10.1038/s41586-021-03312-w. Epub 2021 Feb 9. Nature. 2021. PMID: 33561864 Free PMC article.
Therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections in ferrets.
Cox RM, Wolf JD, Lieberman NA, Lieber CM, Kang HJ, Sticher ZM, Yoon JJ, Andrews MK, Govindarajan M, Krueger RE, Sobolik EB, Natchus MG, Gewirtz AT, deSwart RL, Kolykhalov AA, Hekmatyar K, Sakamoto K, Greninger AL, Plemper RK. Cox RM, et al. Among authors: natchus mg. Nat Commun. 2024 Feb 8;15(1):1189. doi: 10.1038/s41467-024-45418-5. Nat Commun. 2024. PMID: 38331906 Free PMC article.
Orally efficacious broad-spectrum allosteric inhibitor of paramyxovirus polymerase.
Cox RM, Sourimant J, Toots M, Yoon JJ, Ikegame S, Govindarajan M, Watkinson RE, Thibault P, Makhsous N, Lin MJ, Marengo JR, Sticher Z, Kolykhalov AA, Natchus MG, Greninger AL, Lee B, Plemper RK. Cox RM, et al. Among authors: natchus mg. Nat Microbiol. 2020 Oct;5(10):1232-1246. doi: 10.1038/s41564-020-0752-7. Epub 2020 Jul 13. Nat Microbiol. 2020. PMID: 32661315 Free PMC article.
58 results