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Items: 1 to 20 of 199

1.

Protein misfolding and aggregation in Alzheimer's disease and type 2 diabetes mellitus.

Ashraf GM, Greig NH, Khan TA, Hassan I, Tabrez S, Shakil S, Sheikh IA, Zaidi SK, Akram M, Jabir NR, Firoz CK, Naeem A, Alhazza IM, Damanhouri GA, Kamal MA.

CNS Neurol Disord Drug Targets. 2014;13(7):1280-93.

2.

Therapeutic Interventions for the Suppression of Alzheimer's Disease: Quest for a Remedy.

Fazili NA, Naeem A, Ashraf GM, Hua GS, Kamal MA.

Curr Drug Metab. 2015;16(5):346-53. Review.

PMID:
25429669
3.

Induction of amyloidogenicity in wild type HEWL by a dialdehyde: analysis involving multi dimensional approach.

Fazili NA, Bhat WF, Naeem A.

Int J Biol Macromol. 2014 Mar;64:36-44. doi: 10.1016/j.ijbiomac.2013.11.010. Epub 2013 Nov 28.

PMID:
24291768
4.

Exploring the Transition of Human α-Synuclein from Native to the Fibrillar State: Insights into the Pathogenesis of Parkinson's Disease.

Fazili NA, Naeem A.

J Fluoresc. 2016 Sep;26(5):1659-69. doi: 10.1007/s10895-016-1856-6. Epub 2016 Jun 30.

PMID:
27365127
5.

Rifampicin Induced Aggregation of Ovalbumin: Malicious Behaviour of Antibiotics.

Fazili NA, Siddiqui GA, Bhat SA, Afsar M, Furkan M, Naeem A.

Protein Pept Lett. 2015;22(7):644-53.

PMID:
26008186
6.

Anti-fibrillation potency of caffeic acid against an antidepressant induced fibrillogenesis of human α-synuclein: Implications for Parkinson's disease.

Fazili NA, Naeem A.

Biochimie. 2015 Jan;108:178-85. doi: 10.1016/j.biochi.2014.11.011. Epub 2014 Nov 22.

PMID:
25461276
7.
8.

Anti-fibrillation propensity of a flavonoid baicalein against the fibrils of hen egg white lysozyme: potential therapeutics for lysozyme amyloidosis.

Fazili NA, Bhat IA, Bhat WF, Naeem A.

J Biomol Struct Dyn. 2016 Oct;34(10):2102-14. doi: 10.1080/07391102.2015.1108232. Epub 2016 Feb 26.

PMID:
26555198
9.

A partially folded state of ovalbumin at low pH tends to aggregate.

Naeem A, Khan TA, Muzaffar M, Ahmad S, Saleemuddin M.

Cell Biochem Biophys. 2011 Jan;59(1):29-38. doi: 10.1007/s12013-010-9108-x.

PMID:
20703954
10.

Detection and analysis of amorphous aggregates and fibrils of cytochrome c in the presence of phenolic acids.

Amani S, Naeem A.

Int J Biol Macromol. 2013 Jul;58:104-12. doi: 10.1016/j.ijbiomac.2013.03.055. Epub 2013 Mar 27.

PMID:
23541553
11.
12.

Glycation promotes the formation of genotoxic aggregates in glucose oxidase.

Khan TA, Amani S, Naeem A.

Amino Acids. 2012 Sep;43(3):1311-22. doi: 10.1007/s00726-011-1204-8. Epub 2011 Dec 24.

PMID:
22198547
13.

Molten globule of hemoglobin proceeds into aggregates and advanced glycated end products.

Iram A, Alam T, Khan JM, Khan TA, Khan RH, Naeem A.

PLoS One. 2013 Aug 26;8(8):e72075. doi: 10.1371/journal.pone.0072075. eCollection 2013.

14.

Consequential secondary structure alterations and aggregation during prolonged casein glycation.

Jindal S, Naeem A.

J Fluoresc. 2013 May;23(3):367-74. doi: 10.1007/s10895-013-1162-5. Epub 2013 Feb 14.

PMID:
23408088
15.

Detergent induces the formation of IgG aggregates: a multi-methodological approach.

Amani S, Nasim F, Khan TA, Fazili NA, Furkan M, Bhat IA, Khan JM, Khan RH, Naeem A.

Spectrochim Acta A Mol Biomol Spectrosc. 2014;120:151-60. doi: 10.1016/j.saa.2013.09.141. Epub 2013 Oct 9.

PMID:
24184618
16.
17.

Protein folding, misfolding, aggregation and their implications in human diseases: discovering therapeutic ways to amyloid-associated diseases.

Iram A, Naeem A.

Cell Biochem Biophys. 2014 Sep;70(1):51-61. doi: 10.1007/s12013-014-9904-9. Review.

PMID:
24639112
18.

Peroxidase improves the activity of catalase by preventing aggregation during TFE-induced denaturation.

Furkan M, Rizvi A, Alam MT, Naeem A.

J Biomol Struct Dyn. 2017 Feb 16:1-10. doi: 10.1080/07391102.2017.1287007. [Epub ahead of print]

PMID:
28150569
19.

Aloe emodin, an anthroquinone from Aloe vera acts as an anti aggregatory agent to the thermally aggregated hemoglobin.

Furkan M, Alam MT, Rizvi A, Khan K, Ali A, Shamsuzzaman, Naeem A.

Spectrochim Acta A Mol Biomol Spectrosc. 2017 May 15;179:188-193. doi: 10.1016/j.saa.2017.02.014. Epub 2017 Feb 9.

PMID:
28242448
20.

A classical enzyme active center motif lacks catalytic competence until modulated electrostatically.

Pinitglang S, Watts AB, Patel M, Reid JD, Noble MA, Gul S, Bokth A, Naeem A, Patel H, Thomas EW, Sreedharan SK, Verma C, Brocklehurst K.

Biochemistry. 1997 Aug 19;36(33):9968-82.

PMID:
9254592

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