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Effects of dexpramipexole on brain mitochondrial conductances and cellular bioenergetic efficiency.
Alavian KN, Dworetzky SI, Bonanni L, Zhang P, Sacchetti S, Mariggio MA, Onofrj M, Thomas A, Li H, Mangold JE, Signore AP, Demarco U, Demady DR, Nabili P, Lazrove E, Smith PJ, Gribkoff VK, Jonas EA. Alavian KN, et al. Among authors: nabili p. Brain Res. 2012 Mar 29;1446:1-11. doi: 10.1016/j.brainres.2012.01.046. Epub 2012 Jan 28. Brain Res. 2012. PMID: 22364637 Free PMC article.
Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase.
Alavian KN, Li H, Collis L, Bonanni L, Zeng L, Sacchetti S, Lazrove E, Nabili P, Flaherty B, Graham M, Chen Y, Messerli SM, Mariggio MA, Rahner C, McNay E, Shore GC, Smith PJ, Hardwick JM, Jonas EA. Alavian KN, et al. Among authors: nabili p. Nat Cell Biol. 2011 Sep 18;13(10):1224-33. doi: 10.1038/ncb2330. Nat Cell Biol. 2011. PMID: 21926988 Free PMC article.
An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore.
Alavian KN, Beutner G, Lazrove E, Sacchetti S, Park HA, Licznerski P, Li H, Nabili P, Hockensmith K, Graham M, Porter GA Jr, Jonas EA. Alavian KN, et al. Among authors: nabili p. Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10580-5. doi: 10.1073/pnas.1401591111. Epub 2014 Jun 16. Proc Natl Acad Sci U S A. 2014. PMID: 24979777 Free PMC article.