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Items: 14


A conceptual model for the development process of confirmatory adaptive clinical trials within an emergency research network.

Mawocha SC, Fetters MD, Legocki LJ, Guetterman TC, Frederiksen S, Barsan WG, Lewis RJ, Berry DA, Meurer WJ.

Clin Trials. 2017 Jun;14(3):246-254. doi: 10.1177/1740774516688900. Epub 2017 Jan 31.


Attitudes and opinions regarding confirmatory adaptive clinical trials: a mixed methods analysis from the Adaptive Designs Accelerating Promising Trials into Treatments (ADAPT-IT) project.

Meurer WJ, Legocki L, Mawocha S, Frederiksen SM, Guetterman TC, Barsan W, Lewis R, Berry D, Fetters M.

Trials. 2016 Jul 29;17:373. doi: 10.1186/s13063-016-1493-z.


Reflections on the Adaptive Designs Accelerating Promising Trials Into Treatments (ADAPT-IT) Process-Findings from a Qualitative Study.

Guetterman TC, Fetters MD, Legocki LJ, Mawocha S, Barsan WG, Lewis RJ, Berry DA, Meurer WJ.

Clin Res Regul Aff. 2015 Oct 2;32(4):121-130. Epub 2015 Sep 18.


Clinical trialist perspectives on the ethics of adaptive clinical trials: a mixed-methods analysis.

Legocki LJ, Meurer WJ, Frederiksen S, Lewis RJ, Durkalski VL, Berry DA, Barsan WG, Fetters MD.

BMC Med Ethics. 2015 May 3;16:27. doi: 10.1186/s12910-015-0022-z.


The Stroke Hyperglycemia Insulin Network Effort (SHINE) trial: an adaptive trial design case study.

Connor JT, Broglio KR, Durkalski V, Meurer WJ, Johnston KC.

Trials. 2015 Mar 4;16:72. doi: 10.1186/s13063-015-0574-8.


Intracerebral hemorrhage mortality is not changing despite declining incidence.

Zahuranec DB, Lisabeth LD, Sánchez BN, Smith MA, Brown DL, Garcia NM, Skolarus LE, Meurer WJ, Burke JF, Adelman EE, Morgenstern LB.

Neurology. 2014 Jun 17;82(24):2180-6. doi: 10.1212/WNL.0000000000000519. Epub 2014 May 16.


The established status epilepticus trial 2013.

Bleck T, Cock H, Chamberlain J, Cloyd J, Connor J, Elm J, Fountain N, Jones E, Lowenstein D, Shinnar S, Silbergleit R, Treiman D, Trinka E, Kapur J.

Epilepsia. 2013 Sep;54 Suppl 6:89-92. doi: 10.1111/epi.12288.


Platelet-oriented inhibition in new TIA and minor ischemic stroke (POINT) trial: rationale and design.

Johnston SC, Easton JD, Farrant M, Barsan W, Battenhouse H, Conwit R, Dillon C, Elm J, Lindblad A, Morgenstern L, Poisson SN, Palesch Y.

Int J Stroke. 2013 Aug;8(6):479-83. doi: 10.1111/ijs.12129.


Bayesian adaptive trials offer advantages in comparative effectiveness trials: an example in status epilepticus.

Connor JT, Elm JJ, Broglio KR; ESETT and ADAPT-IT Investigators.

J Clin Epidemiol. 2013 Aug;66(8 Suppl):S130-7. doi: 10.1016/j.jclinepi.2013.02.015.


Spinal cord injury neuroprotection and the promise of flexible adaptive clinical trials.

Meurer WJ, Barsan WG.

World Neurosurg. 2014 Sep-Oct;82(3-4):e541-6. doi: 10.1016/j.wneu.2013.06.017. Epub 2013 Jul 9. Review.


Adaptive clinical trials: a partial remedy for the therapeutic misconception?

Meurer WJ, Lewis RJ, Berry DA.

JAMA. 2012 Jun 13;307(22):2377-8. doi: 10.1001/jama.2012.4174. No abstract available.


Effect of insurance status on postacute care among working age stroke survivors.

Skolarus LE, Meurer WJ, Burke JF, Prvu Bettger J, Lisabeth LD.

Neurology. 2012 May 15;78(20):1590-5. doi: 10.1212/WNL.0b013e3182563bf5. Epub 2012 May 2.


An overview of the adaptive designs accelerating promising trials into treatments (ADAPT-IT) project.

Meurer WJ, Lewis RJ, Tagle D, Fetters MD, Legocki L, Berry S, Connor J, Durkalski V, Elm J, Zhao W, Frederiksen S, Silbergleit R, Palesch Y, Berry DA, Barsan WG.

Ann Emerg Med. 2012 Oct;60(4):451-7. doi: 10.1016/j.annemergmed.2012.01.020. Epub 2012 Mar 15.

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