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Items: 1 to 20 of 341

1.

Effect of the Pulmonary Embolism Rule-Out Criteria on subsequent thromboembolic events among low-risk emergency department patients: the PROPER randomized clinical trial.

Malavolta D, Quatela V, Moffat J, Ottolini BB; GrAM (Gruppo di Autoformazione metodologica).

Intern Emerg Med. 2019 Jan 16. doi: 10.1007/s11739-019-02027-1. [Epub ahead of print] No abstract available.

PMID:
30652230
2.

Targeting discriminatory SNPs in Salmonella enterica serovar Heidelberg genomes using RNase H2-dependent PCR.

Labbé G, Rankin MA, Robertson J, Moffat J, Giang E, Lee LK, Ziebell K, MacKinnon J, Laing CR, Parmley EJ, Agunos A, Daignault D, Bekal S, Chui L, MacDonald KA, Hoang L, Slavic D, Ramsay D, Pollari F, Nash JHE, Johnson RP.

J Microbiol Methods. 2018 Dec 25;157:81-87. doi: 10.1016/j.mimet.2018.12.021. [Epub ahead of print]

3.

Functional genomic characterization of a synthetic anti-HER3 antibody reveals a role for ubiquitination by RNF41 in the anti-proliferative response.

Turowec JP, Lau EWT, Wang X, Brown KR, Fellouse FA, Jawanda KK, Pan J, Moffat J, Sidhu S.

J Biol Chem. 2018 Dec 6. pii: jbc.RA118.004420. doi: 10.1074/jbc.RA118.004420. [Epub ahead of print]

4.

Discovery of potent azaindazole leucine-rich repeat kinase 2 (LRRK2) inhibitors possessing a key intramolecular hydrogen bond - Part 2.

Shore DGM, Sweeney ZK, Beresford A, Chan BK, Chen H, Drummond J, Gill A, Kleinheinz T, Liu X, Medhurst AD, McIver EG, Moffat JG, Zhu H, Estrada AA.

Bioorg Med Chem Lett. 2018 Oct 12. pii: S0960-894X(18)30807-2. doi: 10.1016/j.bmcl.2018.10.017. [Epub ahead of print]

PMID:
30522953
5.

Monitoring drug crystallization in percutaneous penetration using localized nano-thermal analysis and photothermal microspectroscopy.

Goh CF, Moffat JG, Craig DQM, Hadgraft J, Lane ME.

Mol Pharm. 2018 Dec 10. doi: 10.1021/acs.molpharmaceut.8b01027. [Epub ahead of print]

PMID:
30525649
6.

Eukaryotic Voltage-Gated Sodium Channels: On Their Origins, Asymmetries, Losses, Diversification and Adaptations.

Fux JE, Mehta A, Moffat J, Spafford JD.

Front Physiol. 2018 Nov 21;9:1406. doi: 10.3389/fphys.2018.01406. eCollection 2018.

7.

Hematopoietic Progenitor Kinase-1 Structure in a Domain-Swapped Dimer.

Wu P, Sneeringer CJ, Pitts KE, Day ES, Chan BK, Wei B, Lehoux I, Mortara K, Li H, Wu J, Franke Y, Moffat JG, Grogan JL, Heffron TP, Wang W.

Structure. 2019 Jan 2;27(1):125-133.e4. doi: 10.1016/j.str.2018.10.025. Epub 2018 Nov 29.

PMID:
30503777
8.

Using Bayesian network modelling to untangle farm management risk factors for bovine viral diarrhoea virus infection.

Han JH, Holter J, Moffat J, Weston JF, Heuer C, Gates MC.

Prev Vet Med. 2018 Dec 1;161:75-82. doi: 10.1016/j.prevetmed.2018.10.014. Epub 2018 Oct 28.

PMID:
30466661
9.

Protocadherin-1 is essential for cell entry by New World hantaviruses.

Jangra RK, Herbert AS, Li R, Jae LT, Kleinfelter LM, Slough MM, Barker SL, Guardado-Calvo P, Román-Sosa G, Dieterle ME, Kuehne AI, Muena NA, Wirchnianski AS, Nyakatura EK, Fels JM, Ng M, Mittler E, Pan J, Bharrhan S, Wec AZ, Lai JR, Sidhu SS, Tischler ND, Rey FA, Moffat J, Brummelkamp TR, Wang Z, Dye JM, Chandran K.

Nature. 2018 Nov;563(7732):559-563. doi: 10.1038/s41586-018-0702-1. Epub 2018 Nov 21.

PMID:
30464266
10.

Lung cancer screening - gaining consensus on next steps - proceedings of a closed workshop in the UK.

Moffat J, Hiom S, Kumar HS, Baldwin DR.

Lung Cancer. 2018 Nov;125:121-127. doi: 10.1016/j.lungcan.2018.07.029. Epub 2018 Jul 21. Review.

PMID:
30429009
11.

Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons.

Gonatopoulos-Pournatzis T, Wu M, Braunschweig U, Roth J, Han H, Best AJ, Raj B, Aregger M, O'Hanlon D, Ellis JD, Calarco JA, Moffat J, Gingras AC, Blencowe BJ.

Mol Cell. 2018 Nov 1;72(3):510-524.e12. doi: 10.1016/j.molcel.2018.10.008.

PMID:
30388412
12.

Pooled Lentiviral CRISPR-Cas9 Screens for Functional Genomics in Mammalian Cells.

Aregger M, Chandrashekhar M, Tong AHY, Chan K, Moffat J.

Methods Mol Biol. 2019;1869:169-188. doi: 10.1007/978-1-4939-8805-1_15.

PMID:
30324523
13.

EPH Profiling of BTIC Populations in Glioblastoma Multiforme Using CyTOF.

Hu AX, Adams JJ, Vora P, Qazi M, Singh SK, Moffat J, Sidhu SS.

Methods Mol Biol. 2019;1869:155-168. doi: 10.1007/978-1-4939-8805-1_14.

PMID:
30324522
14.

A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties.

Pavlovic Z, Adams JJ, Blazer LL, Gakhal AK, Jarvik N, Steinhart Z, Robitaille M, Mascall K, Pan J, Angers S, Moffat J, Sidhu SS.

MAbs. 2018 Nov-Dec;10(8):1157-1167. doi: 10.1080/19420862.2018.1515565. Epub 2018 Sep 25.

PMID:
30183492
15.

Microscopic and Macroscopic Properties of Carbohydrate Solutions in the Ionic Liquid 1-Ethyl-3-methyl-imidazolium Acetate.

Ries ME, Radhi A, Green SM, Moffat J, Budtova T.

J Phys Chem B. 2018 Sep 20;122(37):8763-8771. doi: 10.1021/acs.jpcb.8b06939. Epub 2018 Sep 6.

16.

The role of ARID1B, a BAF chromatin remodeling complex subunit, in neural development and behavior.

Moffat JJ, Jung EM, Ka M, Smith AL, Jeon BT, Santen GWE, Kim WY.

Prog Neuropsychopharmacol Biol Psychiatry. 2019 Mar 8;89:30-38. doi: 10.1016/j.pnpbp.2018.08.021. Epub 2018 Aug 24. Review.

PMID:
30149092
17.

Meeting report: 31st International Conference on Antiviral Research.

Bray M, Andrei G, Ballana E, Carter K, Durantel D, Gentry B, Janeba Z, Moffat J, Oomen CJ, Tarbet B, Riveira-Muñoz E, Esté JA; International Society for Antiviral Research.

Antiviral Res. 2018 Oct;158:88-102. doi: 10.1016/j.antiviral.2018.08.002. Epub 2018 Aug 4. Review.

PMID:
30086336
18.

The shieldin complex mediates 53BP1-dependent DNA repair.

Noordermeer SM, Adam S, Setiaputra D, Barazas M, Pettitt SJ, Ling AK, Olivieri M, Álvarez-Quilón A, Moatti N, Zimmermann M, Annunziato S, Krastev DB, Song F, Brandsma I, Frankum J, Brough R, Sherker A, Landry S, Szilard RK, Munro MM, McEwan A, Goullet de Rugy T, Lin ZY, Hart T, Moffat J, Gingras AC, Martin A, van Attikum H, Jonkers J, Lord CJ, Rottenberg S, Durocher D.

Nature. 2018 Aug;560(7716):117-121. doi: 10.1038/s41586-018-0340-7. Epub 2018 Jul 18.

19.

Cellular Stress Response to Varicella-Zoster Virus Infection of Human Skin Includes Highly Elevated Interleukin-6 Expression.

Jarosinski KW, Carpenter JE, Buckingham EM, Jackson W, Knudtson K, Moffat JF, Kita H, Grose C.

Open Forum Infect Dis. 2018 May 22;5(6):ofy118. doi: 10.1093/ofid/ofy118. eCollection 2018 Jun.

20.

CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions.

Zimmermann M, Murina O, Reijns MAM, Agathanggelou A, Challis R, Tarnauskaitė Ž, Muir M, Fluteau A, Aregger M, McEwan A, Yuan W, Clarke M, Lambros MB, Paneesha S, Moss P, Chandrashekhar M, Angers S, Moffat J, Brunton VG, Hart T, de Bono J, Stankovic T, Jackson AP, Durocher D.

Nature. 2018 Jul;559(7713):285-289. doi: 10.1038/s41586-018-0291-z. Epub 2018 Jul 4.

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