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Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis.
Marmor-Kollet H, Siany A, Kedersha N, Knafo N, Rivkin N, Danino YM, Moens TG, Olender T, Sheban D, Cohen N, Dadosh T, Addadi Y, Ravid R, Eitan C, Toth Cohen B, Hofmann S, Riggs CL, Advani VM, Higginbottom A, Cooper-Knock J, Hanna JH, Merbl Y, Van Den Bosch L, Anderson P, Ivanov P, Geiger T, Hornstein E. Marmor-Kollet H, et al. Among authors: moens tg. Mol Cell. 2020 Dec 3;80(5):876-891.e6. doi: 10.1016/j.molcel.2020.10.032. Epub 2020 Nov 19. Mol Cell. 2020. PMID: 33217318 Free PMC article.
Genetic models of C9orf72: what is toxic?
Moens TG, Partridge L, Isaacs AM. Moens TG, et al. Curr Opin Genet Dev. 2017 Jun;44:92-101. doi: 10.1016/j.gde.2017.01.006. Epub 2017 Mar 29. Curr Opin Genet Dev. 2017. PMID: 28364657 Review.
PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport.
Tziortzouda P, Steyaert J, Scheveneels W, Sicart A, Stoklund Dittlau K, Barbosa Correia AM, Burg T, Pal A, Hermann A, Van Damme P, Moens TG, Van Den Bosch L. Tziortzouda P, et al. Among authors: moens tg. Acta Neuropathol. 2024 Feb 16;147(1):41. doi: 10.1007/s00401-024-02689-y. Acta Neuropathol. 2024. PMID: 38363426 Free PMC article.
G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo.
Simone R, Balendra R, Moens TG, Preza E, Wilson KM, Heslegrave A, Woodling NS, Niccoli T, Gilbert-Jaramillo J, Abdelkarim S, Clayton EL, Clarke M, Konrad MT, Nicoll AJ, Mitchell JS, Calvo A, Chio A, Houlden H, Polke JM, Ismail MA, Stephens CE, Vo T, Farahat AA, Wilson WD, Boykin DW, Zetterberg H, Partridge L, Wray S, Parkinson G, Neidle S, Patani R, Fratta P, Isaacs AM. Simone R, et al. Among authors: moens tg. EMBO Mol Med. 2018 Jan;10(1):22-31. doi: 10.15252/emmm.201707850. EMBO Mol Med. 2018. PMID: 29113975 Free PMC article.
C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1A.
Moens TG, Niccoli T, Wilson KM, Atilano ML, Birsa N, Gittings LM, Holbling BV, Dyson MC, Thoeng A, Neeves J, Glaria I, Yu L, Bussmann J, Storkebaum E, Pardo M, Choudhary JS, Fratta P, Partridge L, Isaacs AM. Moens TG, et al. Acta Neuropathol. 2019 Mar;137(3):487-500. doi: 10.1007/s00401-018-1946-4. Epub 2019 Jan 2. Acta Neuropathol. 2019. PMID: 30604225 Free PMC article.
A genome-wide gene-expression analysis and database in transgenic mice during development of amyloid or tau pathology.
Matarin M, Salih DA, Yasvoina M, Cummings DM, Guelfi S, Liu W, Nahaboo Solim MA, Moens TG, Paublete RM, Ali SS, Perona M, Desai R, Smith KJ, Latcham J, Fulleylove M, Richardson JC, Hardy J, Edwards FA. Matarin M, et al. Among authors: moens tg. Cell Rep. 2015 Feb 3;10(4):633-44. doi: 10.1016/j.celrep.2014.12.041. Epub 2015 Jan 22. Cell Rep. 2015. PMID: 25620700 Free article.