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Items: 1 to 20 of 25


Know your detergents: A case study on detergent background in negative stain electron microscopy.

Gewering T, Januliene D, Ries AB, Moeller A.

J Struct Biol. 2018 Sep;203(3):242-246. doi: 10.1016/j.jsb.2018.05.008. Epub 2018 May 29.


Alpha-synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation.

Betzer C, Lassen LB, Olsen A, Kofoed RH, Reimer L, Gregersen E, Zheng J, Calì T, Gai WP, Chen T, Moeller A, Brini M, Fu Y, Halliday G, Brudek T, Aznar S, Pakkenberg B, Andersen JP, Jensen PH.

EMBO Rep. 2018 May;19(5). pii: e44617. doi: 10.15252/embr.201744617. Epub 2018 Mar 29.


Structure of the human MHC-I peptide-loading complex.

Blees A, Januliene D, Hofmann T, Koller N, Schmidt C, Trowitzsch S, Moeller A, Tampé R.

Nature. 2017 Nov 23;551(7681):525-528. doi: 10.1038/nature24627. Epub 2017 Nov 6.


Acidic Environment Induces Dimerization and Ligand Binding Site Collapse in the Vps10p Domain of Sortilin.

Januliene D, Andersen JL, Nielsen JA, Quistgaard EM, Hansen M, Strandbygaard D, Moeller A, Petersen CM, Madsen P, Thirup SS.

Structure. 2017 Dec 5;25(12):1809-1819.e3. doi: 10.1016/j.str.2017.09.015.


Hidden Twins: SorCS Neuroreceptors Form Stable Dimers.

Januliene D, Manavalan A, Ovesen PL, Pedersen KM, Thirup S, Nykjær A, Moeller A.

J Mol Biol. 2017 Sep 15;429(19):2907-2917. doi: 10.1016/j.jmb.2017.08.006. Epub 2017 Aug 18.


Cryo-EM structure of the replisome reveals multiple interactions coordinating DNA synthesis.

Kulczyk AW, Moeller A, Meyer P, Sliz P, Richardson CC.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):E1848-E1856. doi: 10.1073/pnas.1701252114. Epub 2017 Feb 21.


Conformational states of the full-length glucagon receptor.

Yang L, Yang D, de Graaf C, Moeller A, West GM, Dharmarajan V, Wang C, Siu FY, Song G, Reedtz-Runge S, Pascal BD, Wu B, Potter CS, Zhou H, Griffin PR, Carragher B, Yang H, Wang MW, Stevens RC, Jiang H.

Nat Commun. 2015 Jul 31;6:7859. doi: 10.1038/ncomms8859.


Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.

Kang Y, Zhou XE, Gao X, He Y, Liu W, Ishchenko A, Barty A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Ke J, Tan MH, Zhang C, Moeller A, West GM, Pascal BD, Van Eps N, Caro LN, Vishnivetskiy SA, Lee RJ, Suino-Powell KM, Gu X, Pal K, Ma J, Zhi X, Boutet S, Williams GJ, Messerschmidt M, Gati C, Zatsepin NA, Wang D, James D, Basu S, Roy-Chowdhury S, Conrad CE, Coe J, Liu H, Lisova S, Kupitz C, Grotjohann I, Fromme R, Jiang Y, Tan M, Yang H, Li J, Wang M, Zheng Z, Li D, Howe N, Zhao Y, Standfuss J, Diederichs K, Dong Y, Potter CS, Carragher B, Caffrey M, Jiang H, Chapman HN, Spence JC, Fromme P, Weierstall U, Ernst OP, Katritch V, Gurevich VV, Griffin PR, Hubbell WL, Stevens RC, Cherezov V, Melcher K, Xu HE.

Nature. 2015 Jul 30;523(7562):561-7. doi: 10.1038/nature14656. Epub 2015 Jul 22.


TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switching.

Ye Q, Rosenberg SC, Moeller A, Speir JA, Su TY, Corbett KD.

Elife. 2015 Apr 28;4. doi: 10.7554/eLife.07367.


Distinct conformational spectrum of homologous multidrug ABC transporters.

Moeller A, Lee SC, Tao H, Speir JA, Chang G, Urbatsch IL, Potter CS, Carragher B, Zhang Q.

Structure. 2015 Mar 3;23(3):450-460. doi: 10.1016/j.str.2014.12.013. Epub 2015 Feb 5.


Structural biology. Division of labor in transhydrogenase by alternating proton translocation and hydride transfer.

Leung JH, Schurig-Briccio LA, Yamaguchi M, Moeller A, Speir JA, Gennis RB, Stout CD.

Science. 2015 Jan 9;347(6218):178-81. doi: 10.1126/science.1260451.


Allosteric communication in the dynein motor domain.

Bhabha G, Cheng HC, Zhang N, Moeller A, Liao M, Speir JA, Cheng Y, Vale RD.

Cell. 2014 Nov 6;159(4):857-68. doi: 10.1016/j.cell.2014.10.018.


Engineered nanostructured β-sheet peptides protect membrane proteins.

Tao H, Lee SC, Moeller A, Roy RS, Siu FY, Zimmermann J, Stevens RC, Potter CS, Carragher B, Zhang Q.

Nat Methods. 2013 Aug;10(8):759-61. doi: 10.1038/nmeth.2533. Epub 2013 Jun 30.


Organization of the influenza virus replication machinery.

Moeller A, Kirchdoerfer RN, Potter CS, Carragher B, Wilson IA.

Science. 2012 Dec 21;338(6114):1631-4. doi: 10.1126/science.1227270. Epub 2012 Nov 22.


Movies of ice-embedded particles enhance resolution in electron cryo-microscopy.

Campbell MG, Cheng A, Brilot AF, Moeller A, Lyumkis D, Veesler D, Pan J, Harrison SC, Potter CS, Carragher B, Grigorieff N.

Structure. 2012 Nov 7;20(11):1823-8. doi: 10.1016/j.str.2012.08.026. Epub 2012 Sep 27.


Assembly and channel opening of outer membrane protein in tripartite drug efflux pumps of Gram-negative bacteria.

Xu Y, Moeller A, Jun SY, Le M, Yoon BY, Kim JS, Lee K, Ha NC.

J Biol Chem. 2012 Apr 6;287(15):11740-50. doi: 10.1074/jbc.M111.329375. Epub 2012 Feb 3.


Nucleotide-dependent conformational changes in the N-Ethylmaleimide Sensitive Factor (NSF) and their potential role in SNARE complex disassembly.

Moeller A, Zhao C, Fried MG, Wilson-Kubalek EM, Carragher B, Whiteheart SW.

J Struct Biol. 2012 Feb;177(2):335-43. doi: 10.1016/j.jsb.2011.12.018. Epub 2012 Jan 5.


Initial evaluation of a direct detection device detector for single particle cryo-electron microscopy.

Milazzo AC, Cheng A, Moeller A, Lyumkis D, Jacovetty E, Polukas J, Ellisman MH, Xuong NH, Carragher B, Potter CS.

J Struct Biol. 2011 Dec;176(3):404-8. doi: 10.1016/j.jsb.2011.09.002. Epub 2011 Sep 10.


Recombinant functional multidomain hemoglobin from the gastropod Biomphalaria glabrata.

Moeller V, Dürr R, Sarraf-Zadeh L, Keller S, Heinz S, Hellmann N, Moeller A, Lieb B, Markl J.

IUBMB Life. 2011 May;63(5):323-8. doi: 10.1002/iub.453. Epub 2011 Apr 13.


Funnel-like hexameric assembly of the periplasmic adapter protein in the tripartite multidrug efflux pump in gram-negative bacteria.

Xu Y, Lee M, Moeller A, Song S, Yoon BY, Kim HM, Jun SY, Lee K, Ha NC.

J Biol Chem. 2011 May 20;286(20):17910-20. doi: 10.1074/jbc.M111.238535. Epub 2011 Mar 29.

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