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Items: 1 to 20 of 97


Improving engraftment of hepatocyte transplantation using alpha-1 antitrypsin as an immune modulator.

Lee C, Dhawan A, Iansante V, Filippi C, Mitry R, Tang J, Walker S, Fernandez DaCosta R, Sinha S, Hughes RD, Koulmanda M, Fitzpatrick E.

J Mol Med (Berl). 2019 Apr;97(4):563-577. doi: 10.1007/s00109-019-01747-3. Epub 2019 Feb 28.


Validation of Current Good Manufacturing Practice Compliant Human Pluripotent Stem Cell-Derived Hepatocytes for Cell-Based Therapy.

Blackford SJI, Ng SS, Segal JM, King AJF, Austin AL, Kent D, Moore J, Sheldon M, Ilic D, Dhawan A, Mitry RR, Rashid ST.

Stem Cells Transl Med. 2019 Feb;8(2):124-137. doi: 10.1002/sctm.18-0084. Epub 2018 Nov 19.


A New High Throughput Screening Platform for Cell Encapsulation in Alginate Hydrogel Shows Improved Hepatocyte Functions by Mesenchymal Stromal Cells Co-encapsulation.

Iansante V, Dhawan A, Masmoudi F, Lee CA, Fernandez-Dacosta R, Walker S, Fitzpatrick E, Mitry RR, Filippi C.

Front Med (Lausanne). 2018 Aug 9;5:216. doi: 10.3389/fmed.2018.00216. eCollection 2018.


Imaging-Based Screen Identifies Laminin 411 as a Physiologically Relevant Niche Factor with Importance for i-Hep Applications.

Ong J, Serra MP, Segal J, Cujba AM, Ng SS, Butler R, Millar V, Hatch S, Zimri S, Koike H, Chan K, Bonham A, Walk M, Voss T, Heaton N, Mitry R, Dhawan A, Ebner D, Danovi D, Nakauchi H, Rashid ST.

Stem Cell Reports. 2018 Mar 13;10(3):693-702. doi: 10.1016/j.stemcr.2018.01.025. Epub 2018 Mar 1.


Cryopreserved neonatal hepatocytes may be a source for transplantation: Evaluation of functionality toward clinical use.

Lee CA, Dhawan A, Iansante V, Lehec S, Khorsandi SE, Filippi C, Walker S, Fernandez-Dacosta R, Heaton N, Bansal S, Mitry RR, Fitzpatrick E.

Liver Transpl. 2018 Mar;24(3):394-406. doi: 10.1002/lt.25015.


Human hepatocyte transplantation for liver disease: current status and future perspectives.

Iansante V, Mitry RR, Filippi C, Fitzpatrick E, Dhawan A.

Pediatr Res. 2018 Jan;83(1-2):232-240. doi: 10.1038/pr.2017.284. Epub 2017 Dec 6. Review.


Cryopreservation of Hepatocyte Microbeads for Clinical Transplantation.

Jitraruch S, Dhawan A, Hughes RD, Filippi C, Lehec SC, Glover L, Mitry RR.

Cell Transplant. 2017 Aug;26(8):1341-1354. doi: 10.1177/0963689717720050.


Alginate Encapsulation of Human Hepatocytes and Assessment of Microbeads.

Mitry RR, Jitraruch S, Iansante V, Dhawan A.

Methods Mol Biol. 2017;1506:273-281.


Instant Blood-Mediated Inflammatory Reaction in Hepatocyte Transplantation: Current Status and Future Perspectives.

Lee CA, Dhawan A, Smith RA, Mitry RR, Fitzpatrick E.

Cell Transplant. 2016;25(7):1227-36. doi: 10.3727/096368916X691286. Epub 2016 Mar 18. Review.


Combination of acamprosate and baclofen as a promising therapeutic approach for Parkinson's disease.

Hajj R, Milet A, Toulorge D, Cholet N, Laffaire J, Foucquier J, Robelet S, Mitry R, Guedj M, Nabirotchkin S, Chumakov I, Cohen D.

Sci Rep. 2015 Nov 6;5:16084. doi: 10.1038/srep16084.


The Effect of Intraoperative N-Acetylcysteine on Hepatocellular Injury During Laparoscopic Bariatric Surgery. A Randomised Controlled Trial.

Belgaumkar AP, Carswell KA, Hughes RD, Quaglia A, Dhawan A, Mitry RR, Patel AG.

Obes Surg. 2016 Jun;26(6):1254-65. doi: 10.1007/s11695-015-1904-3.


Changes in Bile Acid Profile After Laparoscopic Sleeve Gastrectomy are Associated with Improvements in Metabolic Profile and Fatty Liver Disease.

Belgaumkar AP, Vincent RP, Carswell KA, Hughes RD, Alaghband-Zadeh J, Mitry RR, le Roux CW, Patel AG.

Obes Surg. 2016 Jun;26(6):1195-202. doi: 10.1007/s11695-015-1878-1.


Permissivity of primary hepatocytes and hepatoma cell lines to support hepatitis C virus infection.

Wilson GK, Farquhar MJ, Meredith L, Dhawan A, Mitry R, Balfe P, McKeating JA.

J Gen Virol. 2015 Jun;96(Pt 6):1369-73. doi: 10.1099/vir.0.000085. Epub 2015 Feb 9.


Alginate microencapsulated hepatocytes optimised for transplantation in acute liver failure.

Jitraruch S, Dhawan A, Hughes RD, Filippi C, Soong D, Philippeos C, Lehec SC, Heaton ND, Longhi MS, Mitry RR.

PLoS One. 2014 Dec 1;9(12):e113609. doi: 10.1371/journal.pone.0113609. eCollection 2014. Erratum in: PLoS One. 2015;10(3):e0119226.


Secretory leukocyte protease inhibitor: a pivotal mediator of anti-inflammatory responses in acetaminophen-induced acute liver failure.

Antoniades CG, Khamri W, Abeles RD, Taams LS, Triantafyllou E, Possamai LA, Bernsmeier C, Mitry RR, O'Brien A, Gilroy D, Goldin R, Heneghan M, Heaton N, Jassem W, Bernal W, Vergani D, Ma Y, Quaglia A, Wendon J, Thursz M.

Hepatology. 2014 Apr;59(4):1564-76. doi: 10.1002/hep.26933. Epub 2014 Feb 28.


Coculture with mesenchymal stem cells results in improved viability and function of human hepatocytes.

Fitzpatrick E, Wu Y, Dhadda P, Hughes RD, Mitry RR, Qin H, Lehec SC, Heaton ND, Dhawan A.

Cell Transplant. 2015;24(1):73-83. doi: 10.3727/096368913X674080. Epub 2013 Oct 18.


Character and temporal evolution of apoptosis in acetaminophen-induced acute liver failure*.

Possamai LA, McPhail MJ, Quaglia A, Zingarelli V, Abeles RD, Tidswell R, Puthucheary Z, Rawal J, Karvellas CJ, Leslie EM, Hughes RD, Ma Y, Jassem W, Shawcross DL, Bernal W, Dharwan A, Heaton ND, Thursz M, Wendon JA, Mitry RR, Antoniades CG.

Crit Care Med. 2013 Nov;41(11):2543-50. doi: 10.1097/CCM.0b013e31829791a2.


Ex vivo magnetic resonance imaging of transplanted hepatocytes in a rat model of acute liver failure.

Puppi J, Modo M, Dhawan A, Lehec SC, Mitry RR, Hughes RD.

Cell Transplant. 2014 Mar;23(3):329-43. doi: 10.3727/096368913X663596. Epub 2013 Feb 5.


Acute liver failure and the brain: a look through the crystal ball.

Ryan JM, Tranah T, Mitry RR, Wendon JA, Shawcross DL.

Metab Brain Dis. 2013 Mar;28(1):7-10. doi: 10.1007/s11011-012-9363-1. Epub 2012 Dec 4. Review.


Analysis of adipokine concentrations in paediatric non-alcoholic fatty liver disease.

Fitzpatrick E, Dew TK, Quaglia A, Sherwood RA, Mitry RR, Dhawan A.

Pediatr Obes. 2012 Dec;7(6):471-9. doi: 10.1111/j.2047-6310.2012.00082.x. Epub 2012 Sep 7.


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