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Phase 2 Study of Radiation Therapy Plus Low Dose Temozolomide Followed by Temozolomide and Irinotecan for Glioblastoma: NRG Oncology RTOG Trial 0420.

Lieberman FS, Wang M, Robins HI, Tsien CI, Curran WJ Jr, Werner-Wasik M, Smith RP, Schultz C, Hartford AC, Zhang P, Mehta MP.

Int J Radiat Oncol Biol Phys. 2018 Nov 26. pii: S0360-3016(18)33955-5. doi: 10.1016/j.ijrobp.2018.11.008. [Epub ahead of print]


Recent advances in managing brain metastasis.

Kotecha R, Gondi V, Ahluwalia MS, Brastianos PK, Mehta MP.

F1000Res. 2018 Nov 9;7. pii: F1000 Faculty Rev-1772. doi: 10.12688/f1000research.15903.1. eCollection 2018. Review.


Low-Grade Glioma Radiotherapy Treatment and Trials.

Wang TJC, Mehta MP.

Neurosurg Clin N Am. 2019 Jan;30(1):111-118. doi: 10.1016/ Epub 2018 Nov 1. Review.


Estimating survival for renal cell carcinoma patients with brain metastases: an update of the Renal Graded Prognostic Assessment tool.

Sperduto PW, Deegan BJ, Li J, Jethwa KR, Brown PD, Lockney N, Beal K, Rana NG, Attia A, Tseng CL, Sahgal A, Shanley R, Sperduto WA, Lou E, Zahra A, Buatti JM, Yu JB, Chiang V, Molitoris JK, Masucci L, Roberge D, Shi DD, Shih HA, Olson A, Kirkpatrick JP, Braunstein S, Sneed P, Mehta MP.

Neuro Oncol. 2018 Nov 12;20(12):1652-1660. doi: 10.1093/neuonc/noy099.


Efficacy of Gastric Electrical Stimulation for Gastroparesis: US/European Comparison.

Burlen J, Runnels M, Mehta M, Andersson S, Ducrotte P, Gourcerol G, Lindberg G, Fullarton G, Abrahamsson H, Al-Juburi A, Lahr C, Rashed H, Abell T.

Gastroenterology Res. 2018 Oct;11(5):349-354. doi: 10.14740/gr1061w. Epub 2018 Oct 1.


Postoperative Management of Resected Brain Metastases: When Can Radiotherapy Be Deferred?

Mehta MP, Kotecha R.

J Clin Oncol. 2018 Oct 8:JCO2018793232. doi: 10.1200/JCO.2018.79.3232. [Epub ahead of print]


MGMT promoter methylation status testing to guide therapy for glioblastoma: refining the approach based on emerging evidence and current challenges.

Mansouri A, Hachem LD, Mansouri S, Nassiri F, Laperriere NJ, Xia D, Lindeman NI, Wen PY, Chakravarti A, Mehta MP, Hegi ME, Stupp R, Aldape KD, Zadeh G.

Neuro Oncol. 2018 Sep 5. doi: 10.1093/neuonc/noy132. [Epub ahead of print]


Pencil beam scanning versus passively scattered proton therapy for unresectable pancreatic cancer.

Chuong M, Badiyan SN, Yam M, Li Z, Langen K, Regine W, Morris C, Snider J 3rd, Mehta M, Huh S, Rutenberg M, Nichols RC.

J Gastrointest Oncol. 2018 Aug;9(4):687-693. doi: 10.21037/jgo.2018.03.14.


Prognostic models for patients with brain metastases after stereotactic radiosurgery with or without whole brain radiotherapy: a validation study.

Rice SR, Bentzen SM, Hanna A, Choi E, Boggs DH, Kwok Y, Hyder J, Feigenberg SJ, Regine WF, Woodworth GF, Eisenberg HM, Yu C, Biggins TF, Barnholtz-Sloan JS, Sperduto PW, Weltman E, Mehta MP.

J Neurooncol. 2018 Nov;140(2):341-349. doi: 10.1007/s11060-018-2958-6. Epub 2018 Aug 21.


Omitting radiosurgery in melanoma brain metastases: a drastic and dangerous de-escalation.

Kruser TJ, Gondi V, Sperduto PW, Brown PD, Mehta MP.

Lancet Oncol. 2018 Aug;19(8):e366. doi: 10.1016/S1470-2045(18)30439-X. No abstract available.


Consolidative Whole-Brain Radiation Therapy Versus Autologous Stem Cell Transplant for Primary Central Nervous System Lymphoma: A Large Dose of Perspective and Perhaps a Lower Dose of Radiation Are in Order.

Bovi JA, Schultz CJ, Mehta MP, Corn BW.

Int J Radiat Oncol Biol Phys. 2018 Sep 1;102(1):59-60. doi: 10.1016/j.ijrobp.2018.04.040. Epub 2018 Apr 22. No abstract available.


Treatment recommendations for elderly patients with newly diagnosed glioblastoma lack worldwide consensus.

Palmer JD, Bhamidipati D, Mehta M, Williams NL, Dicker AP, Werner-Wasik M, Shi W.

J Neurooncol. 2018 Nov;140(2):421-426. doi: 10.1007/s11060-018-2969-3. Epub 2018 Aug 7.


Onco-metabolism: defining the prognostic significance of obesity and diabetes in women with brain metastases from breast cancer.

McCall NS, Simone BA, Mehta M, Zhan T, Ko K, Nowak-Choi K, Rese A, Venkataraman C, Andrews DW, Anne' PR, Dicker AP, Shi W, Simone NL.

Breast Cancer Res Treat. 2018 Nov;172(1):221-230. doi: 10.1007/s10549-018-4880-1. Epub 2018 Jul 18.


Effect of Targeted Therapies on Prognostic Factors, Patterns of Care, and Survival in Patients With Renal Cell Carcinoma and Brain Metastases.

Sperduto PW, Deegan BJ, Li J, Jethwa KR, Brown PD, Lockney N, Beal K, Rana NG, Attia A, Tseng CL, Sahgal A, Shanley R, Sperduto WA, Lou E, Zahra A, Buatti JM, Yu JB, Chiang V, Molitoris JK, Masucci L, Roberge D, Shi DD, Shih HA, Olson A, Kirkpatrick JP, Braunstein S, Sneed P, Mehta MP.

Int J Radiat Oncol Biol Phys. 2018 Jul 15;101(4):845-853. doi: 10.1016/j.ijrobp.2018.04.006. Epub 2018 Apr 12.


Association of MGMT Promoter Methylation Status With Survival Outcomes in Patients With High-Risk Glioma Treated With Radiotherapy and Temozolomide: An Analysis From the NRG Oncology/RTOG 0424 Trial.

Bell EH, Zhang P, Fisher BJ, Macdonald DR, McElroy JP, Lesser GJ, Fleming J, Chakraborty AR, Liu Z, Becker AP, Fabian D, Aldape KD, Ashby LS, Werner-Wasik M, Walker EM, Bahary JP, Kwok Y, Yu HM, Laack NN, Schultz CJ, Gray HJ, Robins HI, Mehta MP, Chakravarti A.

JAMA Oncol. 2018 Oct 1;4(10):1405-1409. doi: 10.1001/jamaoncol.2018.1977.


Endoscopic aspects of temporary gastric electrical stimulator lead placement in patients with gastroparesis and gastroparesis-like syndromes.

Wendorf G, Mehta M, Stocker A, Smith J, Abell T.

VideoGIE. 2018 Mar 7;3(4):112. doi: 10.1016/j.vgie.2018.01.007. eCollection 2018 Apr. No abstract available.


Preoperative Vs Postoperative Radiosurgery For Resected Brain Metastases: A Review.

Prabhu RS, Patel KR, Press RH, Soltys SG, Brown PD, Mehta MP, Asher AL, Burri SH.

Neurosurgery. 2018 May 16. doi: 10.1093/neuros/nyy146. [Epub ahead of print]


Prognostic and predictive factors in patients with brain metastases from solid tumors: A review of published nomograms.

Nieder C, Mehta MP, Geinitz H, Grosu AL.

Crit Rev Oncol Hematol. 2018 Jun;126:13-18. doi: 10.1016/j.critrevonc.2018.03.018. Epub 2018 Mar 29. Review.


Influence of Residual Disease Following Surgical Resection in Newly Diagnosed Glioblastoma on Clinical, Neurocognitive, and Patient Reported Outcomes.

Hall WA, Pugh SL, Wefel JS, Armstrong TS, Gilbert MR, Brachman DG, Werner-Wasik M, Wendland MM, Brown PD, Chao ST, Roof KS, Robins HI, Mehta MP, Curran WJ Jr, Movsas B.

Neurosurgery. 2018 Mar 30. doi: 10.1093/neuros/nyy003. [Epub ahead of print]


Temozolomide, sirolimus and chloroquine is a new therapeutic combination that synergizes to disrupt lysosomal function and cholesterol homeostasis in GBM cells.

Hsu SPC, Kuo JS, Chiang HC, Wang HE, Wang YS, Huang CC, Huang YC, Chi MS, Mehta MP, Chi KH.

Oncotarget. 2018 Jan 3;9(6):6883-6896. doi: 10.18632/oncotarget.23855. eCollection 2018 Jan 23.

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