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Items: 1 to 20 of 145

1.

Publisher Correction: Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice.

Que X, Hung MY, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Määttä A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Ylä-Herttuala S, Mellon PL, Hedrick CC, Ley K, Miller YI, Glass CK, Peterson KL, Binder CJ, Tsimikas S, Witztum JL.

Nature. 2018 Sep;561(7724):E43. doi: 10.1038/s41586-018-0313-x.

PMID:
30013121
2.

Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice.

Que X, Hung MY, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Määttä A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Ylä-Herttuala S, Mellon PL, Hedrick CC, Ley K, Miller YI, Glass CK, Peterson KL, Binder CJ, Tsimikas S, Witztum JL.

Nature. 2018 Jun;558(7709):301-306. doi: 10.1038/s41586-018-0198-8. Epub 2018 Jun 6. Erratum in: Nature. 2018 Sep;561(7724):E43.

PMID:
29875409
3.

Haploinsufficiency of SIX3 Abolishes Male Reproductive Behavior Through Disrupted Olfactory Development, and Impairs Female Fertility Through Disrupted GnRH Neuron Migration.

Pandolfi EC, Hoffmann HM, Schoeller EL, Gorman MR, Mellon PL.

Mol Neurobiol. 2018 Nov;55(11):8709-8727. doi: 10.1007/s12035-018-1013-0. Epub 2018 Mar 27.

PMID:
29589282
4.

Antiandrogen Treatment Ameliorates Reproductive and Metabolic Phenotypes in the Letrozole-Induced Mouse Model of PCOS.

Ryan GE, Malik S, Mellon PL.

Endocrinology. 2018 Apr 1;159(4):1734-1747. doi: 10.1210/en.2017-03218.

PMID:
29471436
5.

Chromatin status and transcription factor binding to gonadotropin promoters in gonadotrope cell lines.

Xie H, Hoffmann HM, Iyer AK, Brayman MJ, Ngo C, Sunshine MJ, Mellon PL.

Reprod Biol Endocrinol. 2017 Oct 24;15(1):86. doi: 10.1186/s12958-017-0304-z.

6.

Transcriptional interaction between cFOS and the homeodomain-binding transcription factor VAX1 on the GnRH promoter controls Gnrh1 expression levels in a GnRH neuron maturation specific manner.

Hoffmann HM, Gong P, Tamrazian A, Mellon PL.

Mol Cell Endocrinol. 2018 Feb 5;461:143-154. doi: 10.1016/j.mce.2017.09.004. Epub 2017 Sep 7.

PMID:
28890143
7.
8.

Bmal1 Is Required for Normal Reproductive Behaviors in Male Mice.

Schoeller EL, Clark DD, Dey S, Cao NV, Semaan SJ, Chao LW, Kauffman AS, Stowers L, Mellon PL.

Endocrinology. 2016 Dec;157(12):4914-4929. Epub 2016 Oct 5.

9.

A Novel Gonadotropin-Releasing Hormone 1 (Gnrh1) Enhancer-Derived Noncoding RNA Regulates Gnrh1 Gene Expression in GnRH Neuronal Cell Models.

Huang PP, Brusman LE, Iyer AK, Webster NJ, Mellon PL.

PLoS One. 2016 Jul 7;11(7):e0158597. doi: 10.1371/journal.pone.0158597. eCollection 2016.

10.

Deletion of Vax1 from Gonadotropin-Releasing Hormone (GnRH) Neurons Abolishes GnRH Expression and Leads to Hypogonadism and Infertility.

Hoffmann HM, Trang C, Gong P, Kimura I, Pandolfi EC, Mellon PL.

J Neurosci. 2016 Mar 23;36(12):3506-18. doi: 10.1523/JNEUROSCI.2723-15.2016.

11.

P16INK4a Upregulation Mediated by SIX6 Defines Retinal Ganglion Cell Pathogenesis in Glaucoma.

Skowronska-Krawczyk D, Zhao L, Zhu J, Weinreb RN, Cao G, Luo J, Flagg K, Patel S, Wen C, Krupa M, Luo H, Ouyang H, Lin D, Wang W, Li G, Xu Y, Li O, Chung C, Yeh E, Jafari M, Ai M, Zhong Z, Shi W, Zheng L, Krawczyk M, Chen D, Shi C, Zin C, Zhu J, Mellon PL, Gao W, Abagyan R, Zhang L, Sun X, Zhong S, Zhuo Y, Rosenfeld MG, Liu Y, Zhang K.

Mol Cell. 2015 Sep 17;59(6):931-40. doi: 10.1016/j.molcel.2015.07.027. Epub 2015 Sep 10.

12.

A Novel Letrozole Model Recapitulates Both the Reproductive and Metabolic Phenotypes of Polycystic Ovary Syndrome in Female Mice.

Kauffman AS, Thackray VG, Ryan GE, Tolson KP, Glidewell-Kenney CA, Semaan SJ, Poling MC, Iwata N, Breen KM, Duleba AJ, Stener-Victorin E, Shimasaki S, Webster NJ, Mellon PL.

Biol Reprod. 2015 Sep;93(3):69. doi: 10.1095/biolreprod.115.131631. Epub 2015 Jul 22.

13.

Absent Progesterone Signaling in Kisspeptin Neurons Disrupts the LH Surge and Impairs Fertility in Female Mice.

Stephens SB, Tolson KP, Rouse ML Jr, Poling MC, Hashimoto-Partyka MK, Mellon PL, Kauffman AS.

Endocrinology. 2015 Sep;156(9):3091-7. doi: 10.1210/en.2015-1300. Epub 2015 Jun 15.

14.

Homeodomain Proteins SIX3 and SIX6 Regulate Gonadotrope-specific Genes During Pituitary Development.

Xie H, Hoffmann HM, Meadows JD, Mayo SL, Trang C, Leming SS, Maruggi C, Davis SW, Larder R, Mellon PL.

Mol Endocrinol. 2015 Jun;29(6):842-55. doi: 10.1210/me.2014-1279. Epub 2015 Apr 27.

15.

KISS1R signals independently of Gαq/11 and triggers LH secretion via the β-arrestin pathway in the male mouse.

Ahow M, Min L, Pampillo M, Nash C, Wen J, Soltis K, Carroll RS, Glidewell-Kenney CA, Mellon PL, Bhattacharya M, Tobet SA, Kaiser UB, Babwah AV.

Endocrinology. 2014 Nov;155(11):4433-46. doi: 10.1210/en.2014-1304. Epub 2014 Aug 22.

16.

Roles of binding elements, FOXL2 domains, and interactions with cJUN and SMADs in regulation of FSHβ.

Roybal LL, Hambarchyan A, Meadows JD, Barakat NH, Pepa PA, Breen KM, Mellon PL, Coss D.

Mol Endocrinol. 2014 Oct;28(10):1640-55. doi: 10.1210/me.2014-1008. Epub 2014 Aug 8.

17.

Heterozygous deletion of ventral anterior homeobox (vax1) causes subfertility in mice.

Hoffmann HM, Tamrazian A, Xie H, Pérez-Millán MI, Kauffman AS, Mellon PL.

Endocrinology. 2014 Oct;155(10):4043-53. doi: 10.1210/en.2014-1277. Epub 2014 Jul 25.

18.

Neurokinin B induces c-fos transcription via protein kinase C and activation of serum response factor and Elk-1 in immortalized GnRH neurons.

Glidewell-Kenney CA, Trang C, Shao PP, Gutierrez-Reed N, Uzo-Okereke AM, Coss D, Mellon PL.

Endocrinology. 2014 Oct;155(10):3909-19. doi: 10.1210/en.2014-1263. Epub 2014 Jul 24.

19.

Influence of stress-induced intermediates on gonadotropin gene expression in gonadotrope cells.

Breen KM, Mellon PL.

Mol Cell Endocrinol. 2014 Mar 25;385(1-2):71-7. doi: 10.1016/j.mce.2013.08.014. Epub 2013 Sep 4. Review.

20.

Gene dosage of Otx2 is important for fertility in male mice.

Larder R, Kimura I, Meadows J, Clark DD, Mayo S, Mellon PL.

Mol Cell Endocrinol. 2013 Sep 5;377(1-2):16-22. doi: 10.1016/j.mce.2013.06.026. Epub 2013 Jun 27.

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