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Items: 1 to 20 of 153

1.

Ultrasound molecular imaging as a non-invasive companion diagnostic for netrin-1 interference therapy in breast cancer.

Wischhusen J, Wilson KE, Delcros JG, Molina-Peña R, Gibert B, Jiang S, Ngo J, Goldschneider D, Mehlen P, Willmann JK, Padilla F.

Theranostics. 2018 Oct 6;8(18):5126-5142. doi: 10.7150/thno.27221. eCollection 2018.

2.

The Proto-oncogene c-Kit Inhibits Tumor Growth by Behaving as a Dependence Receptor.

Wang H, Boussouar A, Mazelin L, Tauszig-Delamasure S, Sun Y, Goldschneider D, Paradisi A, Mehlen P.

Mol Cell. 2018 Nov 1;72(3):413-425.e5. doi: 10.1016/j.molcel.2018.08.040. Epub 2018 Oct 4.

PMID:
30293784
3.

Notch Signaling in the Tumor Microenvironment.

Meurette O, Mehlen P.

Cancer Cell. 2018 Oct 8;34(4):536-548. doi: 10.1016/j.ccell.2018.07.009. Epub 2018 Aug 23. Review.

PMID:
30146333
4.

The dependence receptor TrkC regulates the number of sensory neurons during DRG development.

Ménard M, Costechareyre C, Coelho-Aguiar JM, Jarrosson-Wuilleme L, Rama N, Blachier J, Kindbeiter K, Bozon M, Cabrera JR, Dupin E, Le Douarin N, Mehlen P, Tauszig-Delamasure S.

Dev Biol. 2018 Oct 15;442(2):249-261. doi: 10.1016/j.ydbio.2018.07.022. Epub 2018 Jul 31.

PMID:
30071216
5.

The Ectodysplasin receptor EDAR acts as a tumor suppressor in melanoma by conditionally inducing cell death.

Vial J, Royet A, Cassier P, Tortereau A, Dinvaut S, Maillet D, Gratadou-Hupon L, Creveaux M, Sadier A, Tondeur G, Léon S, Depaepe L, Pantalacci S, de la Fouchardière A, Micheau O, Dalle S, Laudet V, Mehlen P, Castets M.

Cell Death Differ. 2018 May 31. doi: 10.1038/s41418-018-0128-1. [Epub ahead of print]

PMID:
29855541
6.

Dependence receptors - the dark side awakens.

Negulescu AM, Mehlen P.

FEBS J. 2018 Nov;285(21):3909-3924. doi: 10.1111/febs.14507. Epub 2018 May 31. Review.

PMID:
29776009
7.

Hey1- and p53-dependent TrkC proapoptotic activity controls neuroblastoma growth.

Ménard M, Costechareyre C, Ichim G, Blachier J, Neves D, Jarrosson-Wuilleme L, Depping R, Koster J, Saintigny P, Mehlen P, Tauszig-Delamasure S.

PLoS Biol. 2018 May 11;16(5):e2002912. doi: 10.1371/journal.pbio.2002912. eCollection 2018 May.

8.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G.

Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Review.

9.

Commissural neurons transgress the CNS/PNS boundary in absence of ventricular zone-derived netrin 1.

Moreno-Bravo JA, Roig Puiggros S, Blockus H, Dominici C, Zelina P, Mehlen P, Chédotal A.

Development. 2018 Jan 17;145(2). pii: dev159400. doi: 10.1242/dev.159400.

10.

Hepatocellular carcinoma-associated depletion of the netrin-1 receptor Uncoordinated Phenotype-5A (UNC5A) skews the hepatic unfolded protein response towards prosurvival outcomes.

Barnault R, Lahlali T, Plissonnier ML, Romero-López C, Laverdure N, Ducarouge B, Rivoire M, Mehlen P, Zoulim F, Parent R.

Biochem Biophys Res Commun. 2018 Jan 22;495(4):2425-2431. doi: 10.1016/j.bbrc.2017.12.129. Epub 2017 Dec 24.

PMID:
29277614
11.

DNA methylation signal has a major role in the response of human breast cancer cells to the microenvironment.

Mathot P, Grandin M, Devailly G, Souaze F, Cahais V, Moran S, Campone M, Herceg Z, Esteller M, Juin P, Mehlen P, Dante R.

Oncogenesis. 2017 Oct 23;6(10):e390. doi: 10.1038/oncsis.2017.88.

12.

Alu RNA accumulation induces epithelial-to-mesenchymal transition by modulating miR-566 and is associated with cancer progression.

Di Ruocco F, Basso V, Rivoire M, Mehlen P, Ambati J, De Falco S, Tarallo V.

Oncogene. 2018 Feb 1;37(5):627-637. doi: 10.1038/onc.2017.369. Epub 2017 Oct 9.

13.

p53-dependent programmed necrosis controls germ cell homeostasis during spermatogenesis.

Napoletano F, Gibert B, Yacobi-Sharon K, Vincent S, Favrot C, Mehlen P, Girard V, Teil M, Chatelain G, Walter L, Arama E, Mollereau B.

PLoS Genet. 2017 Sep 25;13(9):e1007024. doi: 10.1371/journal.pgen.1007024. eCollection 2017 Sep.

14.

Reciprocal antagonism between the netrin-1 receptor uncoordinated-phenotype-5A (UNC5A) and the hepatitis C virus.

Plissonnier ML, Lahlali T, Raab M, Michelet M, Romero-López C, Rivoire M, Strebhardt K, Durantel D, Levrero M, Mehlen P, Zoulim F, Parent R.

Oncogene. 2017 Nov 30;36(48):6712-6724. doi: 10.1038/onc.2017.271. Epub 2017 Aug 7.

PMID:
28783179
15.

Non-canonical NOTCH3 signalling limits tumour angiogenesis.

Lin S, Negulescu A, Bulusu S, Gibert B, Delcros JG, Ducarouge B, Rama N, Gadot N, Treilleux I, Saintigny P, Meurette O, Mehlen P.

Nat Commun. 2017 Jul 18;8:16074. doi: 10.1038/ncomms16074.

16.

Molecular characterization of Netrin-1 and APP receptor binding: New leads to block the progression of senile plaques in Alzheimer's disease.

Borel F, Marzocca F, Delcros JG, Rama N, Mehlen P, Ferrer JL.

Biochem Biophys Res Commun. 2017 Jul 1;488(3):466-470. doi: 10.1016/j.bbrc.2017.05.056. Epub 2017 May 10.

PMID:
28501620
17.

Floor-plate-derived netrin-1 is dispensable for commissural axon guidance.

Dominici C, Moreno-Bravo JA, Puiggros SR, Rappeneau Q, Rama N, Vieugue P, Bernet A, Mehlen P, Chédotal A.

Nature. 2017 May 18;545(7654):350-354. doi: 10.1038/nature22331. Epub 2017 Apr 26.

18.

Ephrin-B3 supports glioblastoma growth by inhibiting apoptosis induced by the dependence receptor EphA4.

Royet A, Broutier L, Coissieux MM, Malleval C, Gadot N, Maillet D, Gratadou-Hupon L, Bernet A, Nony P, Treilleux I, Honnorat J, Liebl D, Pelletier L, Berger F, Meyronet D, Castets M, Mehlen P.

Oncotarget. 2017 Apr 4;8(14):23750-23759. doi: 10.18632/oncotarget.16077.

19.

Netrin-1 Protects Hepatocytes Against Cell Death Through Sustained Translation During the Unfolded Protein Response.

Lahlali T, Plissonnier ML, Romero-López C, Michelet M, Ducarouge B, Berzal-Herranz A, Zoulim F, Mehlen P, Parent R.

Cell Mol Gastroenterol Hepatol. 2016 Jan 9;2(3):281-301.e9. doi: 10.1016/j.jcmgh.2015.12.011. eCollection 2016 May.

20.

Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes.

Reuten R, Patel TR, McDougall M, Rama N, Nikodemus D, Gibert B, Delcros JG, Prein C, Meier M, Metzger S, Zhou Z, Kaltenberg J, McKee KK, Bald T, Tüting T, Zigrino P, Djonov V, Bloch W, Clausen-Schaumann H, Poschl E, Yurchenco PD, Ehrbar M, Mehlen P, Stetefeld J, Koch M.

Nat Commun. 2016 Nov 30;7:13515. doi: 10.1038/ncomms13515.

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