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Items: 1 to 20 of 127

1.

First-in-human phase 1 study of IT1208, a defucosylated humanized anti-CD4 depleting antibody, in patients with advanced solid tumors.

Shitara K, Ueha S, Shichino S, Aoki H, Ogiwara H, Nakatsura T, Suzuki T, Shimomura M, Yoshikawa T, Shoda K, Kitano S, Yamashita M, Nakayama T, Sato A, Kuroda S, Wakabayashi M, Nomura S, Yokochi S, Ito S, Matsushima K, Doi T.

J Immunother Cancer. 2019 Jul 24;7(1):195. doi: 10.1186/s40425-019-0677-y.

2.

Gli signaling pathway modulates fibroblast activation and facilitates scar formation in pulmonary fibrosis.

Tsukui T, Ueha S, Shichino S, Hashimoto S, Nakajima T, Shiraishi K, Kihara M, Kiyonari H, Inagaki Y, Matsushima K.

Biochem Biophys Res Commun. 2019 Jun 30;514(3):684-690. doi: 10.1016/j.bbrc.2019.05.011. Epub 2019 May 8.

PMID:
31078262
3.

Engraftment and proliferation potential of embryonic lung tissue cells in irradiated mice with emphysema.

Shiraishi K, Shichino S, Tsukui T, Hashimoto S, Ueha S, Matsushima K.

Sci Rep. 2019 Mar 6;9(1):3657. doi: 10.1038/s41598-019-40237-x.

4.

TCR Repertoire Analysis Reveals Mobilization of Novel CD8+ T Cell Clones Into the Cancer-Immunity Cycle Following Anti-CD4 Antibody Administration.

Aoki H, Ueha S, Shichino S, Ogiwara H, Hashimoto SI, Kakimi K, Ito S, Matsushima K.

Front Immunol. 2019 Jan 24;9:3185. doi: 10.3389/fimmu.2018.03185. eCollection 2018.

5.

Combined treatment with HMGN1 and anti-CD4 depleting antibody reverses T cell exhaustion and exerts robust anti-tumor effects in mice.

Chen CY, Ueha S, Ishiwata Y, Yokochi S, Yang, Oppenheim JJ, Ogiwara H, Shichino S, Deshimaru S, Shand FHW, Shibayama S, Matsushima K.

J Immunother Cancer. 2019 Jan 29;7(1):21. doi: 10.1186/s40425-019-0503-6.

6.

Mesenchymal-Epithelial Interactome Analysis Reveals Essential Factors Required for Fibroblast-Free Alveolosphere Formation.

Shiraishi K, Shichino S, Ueha S, Nakajima T, Hashimoto S, Yamazaki S, Matsushima K.

iScience. 2019 Jan 25;11:318-333. doi: 10.1016/j.isci.2018.12.022. Epub 2018 Dec 26.

7.

Transcriptome network analysis identifies protective role of the LXR/SREBP-1c axis in murine pulmonary fibrosis.

Shichino S, Ueha S, Hashimoto S, Otsuji M, Abe J, Tsukui T, Deshimaru S, Nakajima T, Kosugi-Kanaya M, Shand FH, Inagaki Y, Shimano H, Matsushima K.

JCI Insight. 2019 Jan 10;4(1). pii: 122163. doi: 10.1172/jci.insight.122163. [Epub ahead of print]

8.

Lung fibroblasts express a miR-19a-19b-20a sub-cluster to suppress TGF-β-associated fibroblast activation in murine pulmonary fibrosis.

Souma K, Shichino S, Hashimoto S, Ueha S, Tsukui T, Nakajima T, Suzuki HI, Shand FHW, Inagaki Y, Nagase T, Matsushima K.

Sci Rep. 2018 Nov 9;8(1):16642. doi: 10.1038/s41598-018-34839-0.

9.

Reduction of Proliferating Olfactory Cells and Low Expression of Extracellular Matrix Genes Are Hallmarks of the Aged Olfactory Mucosa.

Ueha R, Shichino S, Ueha S, Kondo K, Kikuta S, Nishijima H, Matsushima K, Yamasoba T.

Front Aging Neurosci. 2018 Mar 27;10:86. doi: 10.3389/fnagi.2018.00086. eCollection 2018.

10.

1H, 13C and 15N resonance assignments for a chemokine receptor-binding domain of FROUNT, a cytoplasmic regulator of chemotaxis.

Yoshinaga S, Ishida N, Tsuji T, Sonoda A, Yunoki K, Takeda M, Toda E, Terashima Y, Matsushima K, Terasawa H.

Biomol NMR Assign. 2018 Oct;12(2):259-262. doi: 10.1007/s12104-018-9819-2. Epub 2018 Mar 28.

PMID:
29594928
11.

Single blood transfusion induces the production of donor-specific alloantibodies and regulatory T cells mainly in the spleen.

Ueta H, Kitazawa Y, Sawanobori Y, Ueno T, Ueha S, Matsushima K, Matsuno K.

Int Immunol. 2018 Mar 8;30(2):53-67. doi: 10.1093/intimm/dxx078.

12.

Increased diversity with reduced "diversity evenness" of tumor infiltrating T-cells for the successful cancer immunotherapy.

Hosoi A, Takeda K, Nagaoka K, Iino T, Matsushita H, Ueha S, Aoki S, Matsushima K, Kubo M, Morikawa T, Kitaura K, Suzuki R, Kakimi K.

Sci Rep. 2018 Jan 18;8(1):1058. doi: 10.1038/s41598-018-19548-y.

13.

Long-Lasting Graft-Derived Donor T Cells Contribute to the Pathogenesis of Chronic Graft-versus-Host Disease in Mice.

Kosugi-Kanaya M, Ueha S, Abe J, Shichino S, Shand FHW, Morikawa T, Kurachi M, Shono Y, Sudo N, Yamashita A, Suenaga F, Yokoyama A, Yong W, Imamura M, Teshima T, Matsushima K.

Front Immunol. 2017 Dec 18;8:1842. doi: 10.3389/fimmu.2017.01842. eCollection 2017.

14.

Efficient identification of compounds suppressing protein precipitation via solvent screening using serial deletion mutants of the target protein.

Yunoki K, Yoshinaga S, Takeda M, Nagano R, Tsuchiya Y, Sonoda A, Tsuji T, Hirakane M, Toda E, Terashima Y, Matsushima K, Terasawa H.

Genes Cells. 2018 Feb;23(2):70-79. doi: 10.1111/gtc.12554. Epub 2018 Jan 2.

15.

The HIV co-receptor CCR5 regulates osteoclast function.

Lee JW, Hoshino A, Inoue K, Saitou T, Uehara S, Kobayashi Y, Ueha S, Matsushima K, Yamaguchi A, Imai Y, Iimura T.

Nat Commun. 2017 Dec 20;8(1):2226. doi: 10.1038/s41467-017-02368-5.

16.

Comprehensive single-cell transcriptome analysis reveals heterogeneity in endometrioid adenocarcinoma tissues.

Hashimoto S, Tabuchi Y, Yurino H, Hirohashi Y, Deshimaru S, Asano T, Mariya T, Oshima K, Takamura Y, Ukita Y, Ametani A, Kondo N, Monma N, Takeda T, Misu S, Okayama T, Ikeo K, Saito T, Kaneko S, Suzuki Y, Hattori M, Matsushima K, Torigoe T.

Sci Rep. 2017 Oct 27;7(1):14225. doi: 10.1038/s41598-017-14676-3.

17.

Combination of anti-CD4 antibody treatment and donor lymphocyte infusion ameliorates graft-versus-host disease while preserving graft-versus-tumor effects in murine allogeneic hematopoietic stem cell transplantation.

Ueha S, Yokochi S, Ishiwata Y, Kosugi-Kanaya M, Shono Y, Shibayama S, Ito S, Matsushima K.

Cancer Sci. 2017 Oct;108(10):1967-1973. doi: 10.1111/cas.13346. Epub 2017 Aug 29.

18.

Simian Immunodeficiency Virus Targeting of CXCR3+ CD4+ T Cells in Secondary Lymphoid Organs Is Associated with Robust CXCL10 Expression in Monocyte/Macrophage Subsets.

Fujino M, Sato H, Okamura T, Uda A, Takeda S, Ahmed N, Shichino S, Shiino T, Saito Y, Watanabe S, Sugimoto C, Kuroda MJ, Ato M, Nagai Y, Izumo S, Matsushima K, Miyazawa M, Ansari AA, Villinger F, Mori K.

J Virol. 2017 Jun 9;91(13). pii: e00439-17. doi: 10.1128/JVI.00439-17. Print 2017 Jul 1.

19.

Identification and Preparation of a Novel Chemokine Receptor-Binding Domain in the Cytoplasmic Regulator FROUNT.

Sonoda A, Yoshinaga S, Yunoki K, Ezaki S, Yano K, Takeda M, Toda E, Terashima Y, Matsushima K, Terasawa H.

Mol Biotechnol. 2017 May;59(4-5):141-150. doi: 10.1007/s12033-017-0002-2.

PMID:
28342149
20.

Laryngeal mucus hypersecretion is exacerbated after smoking cessation and ameliorated by glucocorticoid administration.

Ueha R, Ueha S, Kondo K, Nito T, Fujimaki Y, Nishijima H, Tsunoda K, Shand FH, Matsushima K, Yamasoba T.

Toxicol Lett. 2017 Jan 4;265:140-146. doi: 10.1016/j.toxlet.2016.11.023. Epub 2016 Dec 2.

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