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Items: 1 to 20 of 52


Effects of combined brief etomidate anesthesia and postnatal stress on amygdala expression of Cl- cotransporters and corticotropin-releasing hormone and alcohol intake in adult rats.

Yang J, Ju L, Yang C, Xue J, Setlow B, Morey TE, Gravenstein N, Seubert CN, Vasilopoulos T, Martynyuk AE.

Neurosci Lett. 2018 Oct 15;685:83-89. doi: 10.1016/j.neulet.2018.08.019. Epub 2018 Aug 17.


Role of epigenetic mechanisms in transmitting the effects of neonatal sevoflurane exposure to the next generation of male, but not female, rats.

Ju LS, Yang JJ, Morey TE, Gravenstein N, Seubert CN, Resnick JL, Zhang JQ, Martynyuk AE.

Br J Anaesth. 2018 Aug;121(2):406-416. doi: 10.1016/j.bja.2018.04.034. Epub 2018 Jun 5.


Subsequent maternal separation exacerbates neurobehavioral abnormalities in rats neonatally exposed to sevoflurane anesthesia.

Yang J, Ju L, Jia M, Zhang H, Sun X, Ji M, Yang J, Martynyuk AE.

Neurosci Lett. 2017 Nov 20;661:137-142. doi: 10.1016/j.neulet.2017.09.063. Epub 2017 Oct 2.


The Combination of Long-term Ketamine and Extinction Training Contributes to Fear Erasure by Bdnf Methylation.

Ju LS, Yang JJ, Lei L, Xia JY, Luo D, Ji MH, Martynyuk AE, Yang JJ.

Front Cell Neurosci. 2017 Apr 20;11:100. doi: 10.3389/fncel.2017.00100. eCollection 2017.


Role of environmental stressors in determining the developmental outcome of neonatal anesthesia.

Ju LS, Yang JJ, Gravenstein N, Seubert CN, Morey TE, Sumners C, Vasilopoulos T, Yang JJ, Martynyuk AE.

Psychoneuroendocrinology. 2017 Jul;81:96-104. doi: 10.1016/j.psyneuen.2017.04.001. Epub 2017 Apr 7.


Neurodevelopmental effects of anesthesia and environmental factors.

Martynyuk AE, Yang JJ, Zhang JQ.

Oncotarget. 2017 Feb 7;8(6):9009-9010. doi: 10.18632/oncotarget.14694. No abstract available.


Role of histone acetylation in long-term neurobehavioral effects of neonatal Exposure to sevoflurane in rats.

Jia M, Liu WX, Yang JJ, Xu N, Xie ZM, Ju LS, Ji MH, Martynyuk AE, Yang JJ.

Neurobiol Dis. 2016 Jul;91:209-220. doi: 10.1016/j.nbd.2016.03.017. Epub 2016 Mar 18.


Propofol, but not etomidate, increases corticosterone levels and induces long-term alteration in hippocampal synaptic activity in neonatal rats.

Xu C, Seubert CN, Gravenstein N, Martynyuk AE.

Neurosci Lett. 2016 Apr 8;618:1-5. doi: 10.1016/j.neulet.2016.02.045. Epub 2016 Feb 26.


Neurobehavioural abnormalities induced by repeated exposure of neonatal rats to sevoflurane can be aggravated by social isolation and enrichment deprivation initiated after exposure to the anaesthetic.

Zhang MQ, Ji MH, Zhao QS, Jia M, Qiu LL, Yang JJ, Peng YG, Yang JJ, Martynyuk AE.

Br J Anaesth. 2015 Nov;115(5):752-60. doi: 10.1093/bja/aev339.


Role of Steroids in Hyperexcitatory Adverse and Anesthetic Effects of Sevoflurane in Neonatal Rats.

Zhang J, Xu C, Puentes DL, Seubert CN, Gravenstein N, Martynyuk AE.

Neuroendocrinology. 2016;103(5):440-51. doi: 10.1159/000437267. Epub 2015 Jul 1.


Anesthesia with sevoflurane in neonatal rats: Developmental neuroendocrine abnormalities and alleviating effects of the corticosteroid and Cl(-) importer antagonists.

Xu C, Tan S, Zhang J, Seubert CN, Gravenstein N, Sumners C, Vasilopoulos T, Martynyuk AE.

Psychoneuroendocrinology. 2015 Oct;60:173-81. doi: 10.1016/j.psyneuen.2015.06.016. Epub 2015 Jun 25.


Propofol-induced electroencephalographic seizures in neonatal rats: the role of corticosteroids and γ-aminobutyric acid type A receptor-mediated excitation.

Willis J, Zhu W, Perez-Downes J, Tan S, Xu C, Seubert C, Gravenstein N, Martynyuk A.

Anesth Analg. 2015 Feb;120(2):433-9. doi: 10.1213/ANE.0000000000000529.


Endocrine and neurobehavioral abnormalities induced by propofol administered to neonatal rats.

Tan S, Xu C, Zhu W, Willis J, Seubert CN, Gravenstein N, Sumners C, Martynyuk AE.

Anesthesiology. 2014 Nov;121(5):1010-7. doi: 10.1097/ALN.0000000000000366.


Developmental effects of neonatal isoflurane and sevoflurane exposure in rats.

Seubert CN, Zhu W, Pavlinec C, Gravenstein N, Martynyuk AE.

Anesthesiology. 2013 Aug;119(2):358-64. doi: 10.1097/ALN.0b013e318291c04e.


Roles of aldosterone and oxytocin in abnormalities caused by sevoflurane anesthesia in neonatal rats.

Cao W, Pavlinec C, Gravenstein N, Seubert CN, Martynyuk AE.

Anesthesiology. 2012 Oct;117(4):791-800.


Halogenated aromatic amino acid 3,5-dibromo-D: -tyrosine produces beneficial effects in experimental stroke and seizures.

Cao W, Glushakov A, Shah HP, Mecca AP, Sumners C, Shi P, Seubert CN, Martynyuk AE.

Amino Acids. 2011 Apr;40(4):1151-8. doi: 10.1007/s00726-010-0739-4. Epub 2010 Sep 14.


Animal models of brain dysfunction in phenylketonuria.

Martynyuk AE, van Spronsen FJ, Van der Zee EA.

Mol Genet Metab. 2010;99 Suppl 1:S100-5. doi: 10.1016/j.ymgme.2009.10.181.


Bumetanide alleviates epileptogenic and neurotoxic effects of sevoflurane in neonatal rat brain.

Edwards DA, Shah HP, Cao W, Gravenstein N, Seubert CN, Martynyuk AE.

Anesthesiology. 2010 Mar;112(3):567-75. doi: 10.1097/ALN.0b013e3181cf9138.


Efficacy of 3,5-dibromo-L-phenylalanine in rat models of stroke, seizures and sensorimotor gating deficit.

Cao W, Shah HP, Glushakov AV, Mecca AP, Shi P, Sumners C, Seubert CN, Martynyuk AE.

Br J Pharmacol. 2009 Dec;158(8):2005-13.


Halogenated derivatives of aromatic amino acids exhibit balanced antiglutamatergic actions: potential applications for the treatment of neurological and neuropsychiatric disorders.

Martynyuk AE, Seubert CN, Yarotskyy V, Glushakov AV, Gravenstein N, Sumners C, Dennis DM.

Recent Pat CNS Drug Discov. 2006 Nov;1(3):261-70. Review.


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