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Items: 1 to 20 of 64


Evolutionary Dynamics in the RNA Bacteriophage Qβ Depends on the Pattern of Change in Selective Pressures.

Somovilla P, Manrubia S, Lázaro E.

Pathogens. 2019 Jun 18;8(2). pii: E80. doi: 10.3390/pathogens8020080.


Parsimonious Scenario for the Emergence of Viroid-Like Replicons De Novo.

Catalán P, Elena SF, Cuesta JA, Manrubia S.

Viruses. 2019 May 9;11(5). pii: E425. doi: 10.3390/v11050425.


Endemicity and prevalence of multipartite viruses under heterogeneous between-host transmission.

Valdano E, Manrubia S, Gómez S, Arenas A.

PLoS Comput Biol. 2019 Mar 18;15(3):e1006876. doi: 10.1371/journal.pcbi.1006876. eCollection 2019 Mar.


Limited role of spatial self-structuring in emergent trade-offs during pathogen evolution.

Buendía V, Muñoz MA, Manrubia S.

Sci Rep. 2018 Aug 20;8(1):12476. doi: 10.1038/s41598-018-30945-1.


Theoretical approaches to disclosing the emergence and adaptive advantages of multipartite viruses.

Lucía-Sanz A, Aguirre J, Manrubia S.

Curr Opin Virol. 2018 Dec;33:89-95. doi: 10.1016/j.coviro.2018.07.018. Epub 2018 Aug 16. Review.


On the networked architecture of genotype spaces and its critical effects on molecular evolution.

Aguirre J, Catalán P, Cuesta JA, Manrubia S.

Open Biol. 2018 Jul;8(7). pii: 180069. doi: 10.1098/rsob.180069. Review.


Author Correction: The space of genotypes is a network of networks: implications for evolutionary and extinction dynamics.

Yubero P, Manrubia S, Aguirre J.

Sci Rep. 2018 May 3;8(1):7291. doi: 10.1038/s41598-018-25218-w.


Differences in adaptive dynamics determine the success of virus variants that propagate together.

Arribas M, Aguirre J, Manrubia S, Lázaro E.

Virus Evol. 2018 Jan 9;4(1):vex043. doi: 10.1093/ve/vex043. eCollection 2018 Jan.


Adding levels of complexity enhances robustness and evolvability in a multilevel genotype-phenotype map.

Catalán P, Wagner A, Manrubia S, Cuesta JA.

J R Soc Interface. 2018 Jan;15(138). pii: 20170516. doi: 10.1098/rsif.2017.0516.


Multipartite viruses: adaptive trick or evolutionary treat?

Lucía-Sanz A, Manrubia S.

NPJ Syst Biol Appl. 2017 Nov 9;3:34. doi: 10.1038/s41540-017-0035-y. eCollection 2017. Review.


The space of genotypes is a network of networks: implications for evolutionary and extinction dynamics.

Yubero P, Manrubia S, Aguirre J.

Sci Rep. 2017 Oct 23;7(1):13813. doi: 10.1038/s41598-017-14048-x. Erratum in: Sci Rep. 2018 May 3;8(1):7291.


Disentangling the effects of selection and loss bias on gene dynamics.

Iranzo J, Cuesta JA, Manrubia S, Katsnelson MI, Koonin EV.

Proc Natl Acad Sci U S A. 2017 Jul 11;114(28):E5616-E5624. doi: 10.1073/pnas.1704925114. Epub 2017 Jun 26.


Distribution of genotype network sizes in sequence-to-structure genotype-phenotype maps.

Manrubia S, Cuesta JA.

J R Soc Interface. 2017 Apr;14(129). pii: 20160976. doi: 10.1098/rsif.2016.0976.


Internal Disequilibria and Phenotypic Diversification during Replication of Hepatitis C Virus in a Noncoevolving Cellular Environment.

Moreno E, Gallego I, Gregori J, Lucía-Sanz A, Soria ME, Castro V, Beach NM, Manrubia S, Quer J, Esteban JI, Rice CM, Gómez J, Gastaminza P, Domingo E, Perales C.

J Virol. 2017 Apr 28;91(10). pii: e02505-16. doi: 10.1128/JVI.02505-16. Print 2017 May 15.


Adaptive multiscapes: an up-to-date metaphor to visualize molecular adaptation.

Catalán P, Arias CF, Cuesta JA, Manrubia S.

Biol Direct. 2017 Feb 28;12(1):7. doi: 10.1186/s13062-017-0178-1.


Enumerating secondary structures and structural moieties for circular RNAs.

Cuesta JA, Manrubia S.

J Theor Biol. 2017 Apr 21;419:375-382. doi: 10.1016/j.jtbi.2017.02.024. Epub 2017 Feb 21.


The vast unknown microbial biosphere.

Pedrós-Alió C, Manrubia S.

Proc Natl Acad Sci U S A. 2016 Jun 14;113(24):6585-7. doi: 10.1073/pnas.1606105113. Epub 2016 Jun 2. No abstract available.


Demography-based adaptive network model reproduces the spatial organization of human linguistic groups.

Capitán JA, Manrubia S.

Phys Rev E Stat Nonlin Soft Matter Phys. 2015 Dec;92(6):062811. doi: 10.1103/PhysRevE.92.062811. Epub 2015 Dec 9.


Getting to Know Viral Evolutionary Strategies: Towards the Next Generation of Quasispecies Models.

Manrubia S, Lázaro E.

Curr Top Microbiol Immunol. 2016;392:201-17. doi: 10.1007/82_2015_457. Review.


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