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Are large clinical trials in orthopaedic trauma justified?
BMC Musculoskelet Disord. 2018 Apr 20;19(1):124. doi: 10.1186/s12891-018-2029-3.
BMC Musculoskelet Disord. 2018.
PMID: 29678204
Free PMC article.
A Trial of Wound Irrigation in the Initial Management of Open Fracture Wounds.
FLOW Investigators; Bhandari M, Jeray KJ, Petrisor BA, Devereaux PJ, Heels-Ansdell D, Schemitsch EH, Anglen J, Della Rocca GJ, Jones C, Kreder H, Liew S, McKay P, Papp S, Sancheti P, Sprague S, Stone TB, Sun X, Tanner SL, Tornetta P 3rd, Tufescu T, Walter S, Guyatt GH.
FLOW Investigators, et al.
N Engl J Med. 2015 Dec 31;373(27):2629-41. doi: 10.1056/NEJMoa1508502. Epub 2015 Oct 8.
N Engl J Med. 2015.
PMID: 26448371
Free article.
Clinical Trial.
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Wound irrigation does not affect health-related quality of life after open fractures: results of a randomized controlled trial.
Sprague S, Petrisor B, Jeray K, McKay P, Heels-Ansdell D, Schemitsch E, Liew S, Guyatt G, Walter SD, Bhandari M; FLOW Investigators.
Sprague S, et al.
Bone Joint J. 2018 Jan;100-B(1):88-94. doi: 10.1302/0301-620X.100B1.BJJ-2017-0955.R1.
Bone Joint J. 2018.
PMID: 29305456
Free PMC article.
Clinical Trial.
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