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A neutralizing anti-fibroblast growth factor (FGF) 8 monoclonal antibody shows anti-tumor activity against FGF8b-expressing LNCaP xenografts in androgen-dependent and -independent conditions.
Maruyama-Takahashi K, Shimada N, Imada T, Maekawa-Tokuda Y, Ishii T, Ouchi J, Kusaka H, Miyaji H, Akinaga S, Tanaka A, Shitara K. Maruyama-Takahashi K, et al. Among authors: maekawa tokuda y. Prostate. 2008 May 1;68(6):640-50. doi: 10.1002/pros.20728. Prostate. 2008. PMID: 18213631
A neutralizing anti-fibroblast growth factor 8 monoclonal antibody shows potent antitumor activity against androgen-dependent mouse mammary tumors in vivo.
Shimada N, Ishii T, Imada T, Takaba K, Sasaki Y, Maruyama-Takahashi K, Maekawa-Tokuda Y, Kusaka H, Akinaga S, Tanaka A, Shitara K. Shimada N, et al. Among authors: maekawa tokuda y. Clin Cancer Res. 2005 May 15;11(10):3897-904. doi: 10.1158/1078-0432.CCR-04-2358. Clin Cancer Res. 2005. PMID: 15897591