MacKenzie ED[Author] - Search Results

Year	Number of Results
1872	1
1988	1
1989	2
1990	1
1993	1
1997	1
2005	1
2007	1
2008	1
2009	1
2011	1
2012	1
2013	2
2015	2
2024	0

1

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase.

Selak MA, Armour SM, MacKenzie ED, Boulahbel H, Watson DG, Mansfield KD, Pan Y, Simon MC, Thompson CB, Gottlieb E. Selak MA, et al. Among authors: mackenzie ed. Cancer Cell. 2005 Jan;7(1):77-85. doi: 10.1016/j.ccr.2004.11.022. Cancer Cell. 2005. PMID: 15652751 Free article.

2

Fumarate induces redox-dependent senescence by modifying glutathione metabolism.

Zheng L, Cardaci S, Jerby L, MacKenzie ED, Sciacovelli M, Johnson TI, Gaude E, King A, Leach JD, Edrada-Ebel R, Hedley A, Morrice NA, Kalna G, Blyth K, Ruppin E, Frezza C, Gottlieb E. Zheng L, et al. Among authors: mackenzie ed. Nat Commun. 2015 Jan 23;6:6001. doi: 10.1038/ncomms7001. Nat Commun. 2015. PMID: 25613188 Free PMC article.

3

Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis.

Cardaci S, Zheng L, MacKay G, van den Broek NJ, MacKenzie ED, Nixon C, Stevenson D, Tumanov S, Bulusu V, Kamphorst JJ, Vazquez A, Fleming S, Schiavi F, Kalna G, Blyth K, Strathdee D, Gottlieb E. Cardaci S, et al. Among authors: mackenzie ed. Nat Cell Biol. 2015 Oct;17(10):1317-26. doi: 10.1038/ncb3233. Epub 2015 Aug 24. Nat Cell Biol. 2015. PMID: 26302408 Free PMC article.

4

HIF-independent role of prolyl hydroxylases in the cellular response to amino acids.

Durán RV, MacKenzie ED, Boulahbel H, Frezza C, Heiserich L, Tardito S, Bussolati O, Rocha S, Hall MN, Gottlieb E. Durán RV, et al. Among authors: mackenzie ed. Oncogene. 2013 Sep 19;32(38):4549-56. doi: 10.1038/onc.2012.465. Epub 2012 Oct 22. Oncogene. 2013. PMID: 23085753 Free PMC article.

5

Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells.

Zheng L, MacKenzie ED, Karim SA, Hedley A, Blyth K, Kalna G, Watson DG, Szlosarek P, Frezza C, Gottlieb E. Zheng L, et al. Among authors: mackenzie ed. Cancer Metab. 2013 Mar 21;1(1):12. doi: 10.1186/2049-3002-1-12. Cancer Metab. 2013. PMID: 24280230 Free PMC article.

6

The site of the breakpoint within the bcr is a prognostic factor in Philadelphia-positive CML patients.

Mills KI, MacKenzie ED, Birnie GD. Mills KI, et al. Among authors: mackenzie ed. Blood. 1988 Oct;72(4):1237-41. Blood. 1988. PMID: 3167206 Free article.

7

Cardiolipin provides an essential activating platform for caspase-8 on mitochondria.

Gonzalvez F, Schug ZT, Houtkooper RH, MacKenzie ED, Brooks DG, Wanders RJ, Petit PX, Vaz FM, Gottlieb E. Gonzalvez F, et al. Among authors: mackenzie ed. J Cell Biol. 2008 Nov 17;183(4):681-96. doi: 10.1083/jcb.200803129. Epub 2008 Nov 10. J Cell Biol. 2008. PMID: 19001123 Free PMC article.

8

Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells.

MacKenzie ED, Selak MA, Tennant DA, Payne LJ, Crosby S, Frederiksen CM, Watson DG, Gottlieb E. MacKenzie ED, et al. Mol Cell Biol. 2007 May;27(9):3282-9. doi: 10.1128/MCB.01927-06. Epub 2007 Feb 26. Mol Cell Biol. 2007. PMID: 17325041 Free PMC article.

9

Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.

Frezza C, Zheng L, Folger O, Rajagopalan KN, MacKenzie ED, Jerby L, Micaroni M, Chaneton B, Adam J, Hedley A, Kalna G, Tomlinson IP, Pollard PJ, Watson DG, Deberardinis RJ, Shlomi T, Ruppin E, Gottlieb E. Frezza C, et al. Among authors: mackenzie ed. Nature. 2011 Aug 17;477(7363):225-8. doi: 10.1038/nature10363. Nature. 2011. PMID: 21849978

10

AP-1-mediated invasion requires increased expression of the hyaluronan receptor CD44.

Lamb RF, Hennigan RF, Turnbull K, Katsanakis KD, MacKenzie ED, Birnie GD, Ozanne BW. Lamb RF, et al. Among authors: mackenzie ed. Mol Cell Biol. 1997 Feb;17(2):963-76. doi: 10.1128/MCB.17.2.963. Mol Cell Biol. 1997. PMID: 9001250 Free PMC article.

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