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Items: 1 to 20 of 32


The NTP binding site of the polymerase ribozyme.

Akoopie A, Müller UF.

Nucleic Acids Res. 2018 Nov 16;46(20):10589-10597. doi: 10.1093/nar/gky898.


Cotranscriptional 3'-End Processing of T7 RNA Polymerase Transcripts by a Smaller HDV Ribozyme.

Akoopie A, Müller UF.

J Mol Evol. 2018 Aug;86(7):425-430. doi: 10.1007/s00239-018-9861-9. Epub 2018 Aug 11.


Analysis of in vitro evolution reveals the underlying distribution of catalytic activity among random sequences.

Pressman A, Moretti JE, Campbell GW, Müller UF, Chen IA.

Nucleic Acids Res. 2017 Oct 13;45(18):10922. doi: 10.1093/nar/gkx816. No abstract available.


Analysis of in vitro evolution reveals the underlying distribution of catalytic activity among random sequences.

Pressman A, Moretti JE, Campbell GW, Müller UF, Chen IA.

Nucleic Acids Res. 2017 Aug 21;45(14):8167-8179. doi: 10.1093/nar/gkx540.


Metabolic syndrome in patients on first-line antiretroviral therapy containing zidovudine or tenofovir in rural Lesotho, Southern Africa.

Labhardt ND, Müller UF, Ringera I, Ehmer J, Motlatsi MM, Pfeiffer K, Hobbins MA, Muhairwe JA, Muser J, Hatz C.

Trop Med Int Health. 2017 Jun;22(6):725-733. doi: 10.1111/tmi.12872. Epub 2017 May 4.


Design and Experimental Evolution of trans-Splicing Group I Intron Ribozymes.

Müller UF.

Molecules. 2017 Jan 2;22(1). pii: E75. doi: 10.3390/molecules22010075. Review.


Lower temperature optimum of a smaller, fragmented triphosphorylation ribozyme.

Akoopie A, Müller UF.

Phys Chem Chem Phys. 2016 Jul 27;18(30):20118-25. doi: 10.1039/c6cp00672h.


A Faster Triphosphorylation Ribozyme.

Dolan GF, Akoopie A, Müller UF.

PLoS One. 2015 Nov 6;10(11):e0142559. doi: 10.1371/journal.pone.0142559. eCollection 2015.


Increased efficiency of evolved group I intron spliceozymes by decreased side product formation.

Amini ZN, Müller UF.

RNA. 2015 Aug;21(8):1480-9. doi: 10.1261/rna.051888.115. Epub 2015 Jun 23.


RNA synthesis by in vitro selected ribozymes for recreating an RNA world.

Martin LL, Unrau PJ, Müller UF.

Life (Basel). 2015 Jan 20;5(1):247-68. doi: 10.3390/life5010247. Review.


Spliceozymes: ribozymes that remove introns from pre-mRNAs in trans.

Amini ZN, Olson KE, Müller UF.

PLoS One. 2014 Jul 11;9(7):e101932. doi: 10.1371/journal.pone.0101932. eCollection 2014.


Citric acid and the RNA world.

Müller UF, Tor Y.

Angew Chem Int Ed Engl. 2014 May 19;53(21):5245-7. doi: 10.1002/anie.201400847. No abstract available.


In vivo evolution of a catalytic RNA couples trans-splicing to translation.

Olson KE, Dolan GF, Müller UF.

PLoS One. 2014 Jan 23;9(1):e86473. doi: 10.1371/journal.pone.0086473. eCollection 2014.


A ribozyme that triphosphorylates RNA 5'-hydroxyl groups.

Moretti JE, Müller UF.

Nucleic Acids Res. 2014 Apr;42(7):4767-78. doi: 10.1093/nar/gkt1405. Epub 2014 Jan 21.


Trans-splicing with the group I intron ribozyme from Azoarcus.

Dolan GF, Müller UF.

RNA. 2014 Feb;20(2):202-13. doi: 10.1261/rna.041012.113. Epub 2013 Dec 16.


Low selection pressure aids the evolution of cooperative ribozyme mutations in cells.

Amini ZN, Müller UF.

J Biol Chem. 2013 Nov 15;288(46):33096-106. doi: 10.1074/jbc.M113.511469. Epub 2013 Oct 2.


An in vivo selection method to optimize trans-splicing ribozymes.

Olson KE, Müller UF.

RNA. 2012 Mar;18(3):581-9. doi: 10.1261/rna.028472.111. Epub 2012 Jan 24.


Computational prediction of efficient splice sites for trans-splicing ribozymes.

Meluzzi D, Olson KE, Dolan GF, Arya G, Müller UF.

RNA. 2012 Mar;18(3):590-602. doi: 10.1261/rna.029884.111. Epub 2012 Jan 24.


Arginine cofactors on the polymerase ribozyme.

Yao C, Moretti JE, Struss PE, Spall JA, Müller UF.

PLoS One. 2011;6(9):e25030. doi: 10.1371/journal.pone.0025030. Epub 2011 Sep 20.


Polymerase ribozyme efficiency increased by G/T-rich DNA oligonucleotides.

Yao C, Müller UF.

RNA. 2011 Jul;17(7):1274-81. doi: 10.1261/rna.2726811. Epub 2011 May 27.

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