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Items: 1 to 20 of 66


Impact of abrupt versus gradual correction of mitral and tricuspid regurgitation: a modelling study.

Walmsley J, Squara P, Wolfhard U, Cornelussen R, Lumens J.

EuroIntervention. 2019 Nov 20;15(10):902-911. doi: 10.4244/EIJ-D-19-00598.


Large vessels as a tree of transmission lines incorporated in the CircAdapt whole-heart model: A computational tool to examine heart-vessel interaction.

Heusinkveld MHG, Huberts W, Lumens J, Arts T, Delhaas T, Reesink KD.

PLoS Comput Biol. 2019 Jul 15;15(7):e1007173. doi: 10.1371/journal.pcbi.1007173. eCollection 2019 Jul.


Value of Speckle Tracking-Based Deformation Analysis in Screening Relatives of Patients With Asymptomatic Dilated Cardiomyopathy.

Verdonschot JAJ, Merken JJ, Brunner-La Rocca HP, Hazebroek MR, Eurlings CGMJ, Thijssen E, Wang P, Weerts J, van Empel V, Schummers G, Schreckenberg M, van den Wijngaard A, Lumens J, Brunner HG, Heymans SRB, Krapels IPC, Knackstedt C.

JACC Cardiovasc Imaging. 2019 Jun 12. pii: S1936-878X(19)30429-2. doi: 10.1016/j.jcmg.2019.02.032. [Epub ahead of print]


Augmentation index is not a proxy for wave reflection magnitude: mechanistic analysis using a computational model.

Heusinkveld MHG, Delhaas T, Lumens J, Huberts W, Spronck B, Hughes AD, Reesink KD.

J Appl Physiol (1985). 2019 Aug 1;127(2):491-500. doi: 10.1152/japplphysiol.00769.2018. Epub 2019 May 30.


Opposing Wall Pushing and Stretching: Response to Cardiac Resynchronization Therapy Requires Electrical Delay and Viability.

Gorcsan J 3rd, Lumens J.

JACC Cardiovasc Imaging. 2019 Mar 8. pii: S1936-878X(19)30112-3. doi: 10.1016/j.jcmg.2019.01.013. [Epub ahead of print] No abstract available.


The Left and Right Ventricles Respond Differently to Variation of Pacing Delays in Cardiac Resynchronization Therapy: A Combined Experimental- Computational Approach.

Willemen E, Schreurs R, Huntjens PR, Strik M, Plank G, Vigmond E, Walmsley J, Vernooy K, Delhaas T, Prinzen FW, Lumens J.

Front Physiol. 2019 Feb 1;10:17. doi: 10.3389/fphys.2019.00017. eCollection 2019.


AntagomiR-103 and -107 Treatment Affects Cardiac Function and Metabolism.

Rech M, Kuhn AR, Lumens J, Carai P, van Leeuwen R, Verhesen W, Verjans R, Lecomte J, Liu Y, Luiken JJFP, Mohren R, Cillero-Pastor B, Heymans S, Knoops K, van Bilsen M, Schroen B.

Mol Ther Nucleic Acids. 2019 Mar 1;14:424-437. doi: 10.1016/j.omtn.2018.12.010. Epub 2018 Dec 22.


Relative Impact of Right Ventricular Electromechanical Dyssynchrony Versus Pulmonary Regurgitation on Right Ventricular Dysfunction and Exercise Intolerance in Patients After Repair of Tetralogy of Fallot.

Lumens J, Fan CS, Walmsley J, Yim D, Manlhiot C, Dragulescu A, Grosse-Wortmann L, Mertens L, Prinzen FW, Delhaas T, Friedberg MK.

J Am Heart Assoc. 2019 Jan 22;8(2):e010903. doi: 10.1161/JAHA.118.010903.


Pathophysiology of the right ventricle and of the pulmonary circulation in pulmonary hypertension: an update.

Vonk Noordegraaf A, Chin KM, Haddad F, Hassoun PM, Hemnes AR, Hopkins SR, Kawut SM, Langleben D, Lumens J, Naeije R.

Eur Respir J. 2019 Jan 24;53(1). pii: 1801900. doi: 10.1183/13993003.01900-2018. Print 2019 Jan.


Uniqueness of local myocardial strain patterns with respect to activation time and contractility of the failing heart: a computational study.

Kirn B, Walmsley J, Lumens J.

Biomed Eng Online. 2018 Dec 5;17(1):182. doi: 10.1186/s12938-018-0614-1.


Linking cross-bridge cycling kinetics to response to cardiac resynchronization therapy: a multiscale modelling study.

Dupuis LJ, Arts T, Prinzen FW, Delhaas T, Lumens J.

Europace. 2018 Nov 1;20(suppl_3):iii87-iii93. doi: 10.1093/europace/euy230.


Computational models in cardiology.

Niederer SA, Lumens J, Trayanova NA.

Nat Rev Cardiol. 2019 Feb;16(2):100-111. doi: 10.1038/s41569-018-0104-y. Review.


Adding Speckle-Tracking Echocardiography to Visual Assessment of Systolic Wall Motion Abnormalities Improves the Detection of Myocardial Infarction.

van Mourik MJW, Zaar DVJ, Smulders MW, Heijman J, Lumens J, Dokter JE, Lima Passos V, Schalla S, Knackstedt C, Schummers G, Gjesdal O, Edvardsen T, Bekkers SCAM.

J Am Soc Echocardiogr. 2019 Jan;32(1):65-73. doi: 10.1016/j.echo.2018.09.007. Epub 2018 Oct 17.


High tension in sarcomeres hinders myocardial relaxation: A computational study.

Dupuis LJ, Lumens J, Arts T, Delhaas T.

PLoS One. 2018 Oct 4;13(10):e0204642. doi: 10.1371/journal.pone.0204642. eCollection 2018.


Heart Failure With Recovered Ejection Fraction.

Merken J, Brunner-La Rocca HP, Weerts J, Verdonschot J, Hazebroek M, Schummers G, Schreckenberg M, Lumens J, Heymans S, Knackstedt C.

J Am Coll Cardiol. 2018 Sep 25;72(13):1557-1558. doi: 10.1016/j.jacc.2018.06.070. No abstract available.


Systolic Stretch Characterizes the Electromechanical Substrate Responsive to Cardiac Resynchronization Therapy.

Gorcsan J 3rd, Anderson CP, Tayal B, Sugahara M, Walmsley J, Starling RC, Lumens J.

JACC Cardiovasc Imaging. 2019 Sep;12(9):1741-1752. doi: 10.1016/j.jcmg.2018.07.013. Epub 2018 Sep 12.


Electrical Substrates Driving Response to Cardiac Resynchronization Therapy: A Combined Clinical-Computational Evaluation.

Huntjens PR, Ploux S, Strik M, Walmsley J, Ritter P, Haissaguerre M, Prinzen FW, Delhaas T, Lumens J, Bordachar P.

Circ Arrhythm Electrophysiol. 2018 Apr;11(4):e005647. doi: 10.1161/CIRCEP.117.005647.


The Prognostic Value of Right Ventricular Deformation Imaging in Early Arrhythmogenic Right Ventricular Cardiomyopathy.

Mast TP, Taha K, Cramer MJ, Lumens J, van der Heijden JF, Bouma BJ, van den Berg MP, Asselbergs FW, Doevendans PA, Teske AJ.

JACC Cardiovasc Imaging. 2019 Mar;12(3):446-455. doi: 10.1016/j.jcmg.2018.01.012. Epub 2018 Mar 14.


Clinical Applications of Patient-Specific Models: The Case for a Simple Approach.

Holmes JW, Lumens J.

J Cardiovasc Transl Res. 2018 Apr;11(2):71-79. doi: 10.1007/s12265-018-9787-z. Epub 2018 Feb 16. Review.


LBBB and High Afterload: A Dangerous Liaison?

Prinzen FW, Willemen E, Lumens J.

JACC Cardiovasc Imaging. 2019 Jun;12(6):978-980. doi: 10.1016/j.jcmg.2017.12.002. Epub 2018 Jan 17. No abstract available.


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