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Items: 1 to 20 of 58


A structural model of the human serotonin transporter in an outward-occluded state.

Hellsberg E, Ecker GF, Stary-Weinzinger A, Forrest LR.

PLoS One. 2019 Jun 28;14(6):e0217377. doi: 10.1371/journal.pone.0217377. eCollection 2019.


Interpretation of spectroscopic data using molecular simulations for the secondary active transporter BetP.

Leone V, Waclawska I, Kossmann K, Koshy C, Sharma M, Prisner TF, Ziegler C, Endeward B, Forrest LR.

J Gen Physiol. 2019 Mar 4;151(3):381-394. doi: 10.1085/jgp.201812111. Epub 2019 Feb 6.


EncoMPASS: an online database for analyzing structure and symmetry in membrane proteins.

Sarti E, Aleksandrova AA, Ganta SK, Yavatkar AS, Forrest LR.

Nucleic Acids Res. 2019 Jan 8;47(D1):D315-D321. doi: 10.1093/nar/gky952.


Structural elements required for coupling ion and substrate transport in the neurotransmitter transporter homolog LeuT.

Zhang YW, Tavoulari S, Sinning S, Aleksandrova AA, Forrest LR, Rudnick G.

Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):E8854-E8862. doi: 10.1073/pnas.1716870115. Epub 2018 Sep 4.


Structural models of the NaPi-II sodium-phosphate cotransporters.

Fenollar-Ferrer C, Forrest LR.

Pflugers Arch. 2019 Jan;471(1):43-52. doi: 10.1007/s00424-018-2197-x. Epub 2018 Sep 3. Review.


The ins and outs of vesicular monoamine transporters.

Yaffe D, Forrest LR, Schuldiner S.

J Gen Physiol. 2018 May 7;150(5):671-682. doi: 10.1085/jgp.201711980. Epub 2018 Apr 17. Review.


Asymmetry of inverted-topology repeats in the AE1 anion exchanger suggests an elevator-like mechanism.

Ficici E, Faraldo-Gómez JD, Jennings ML, Forrest LR.

J Gen Physiol. 2017 Dec 4;149(12):1149-1164. doi: 10.1085/jgp.201711836. Epub 2017 Nov 22.


Conformational dynamics of a neurotransmitter:sodium symporter in a lipid bilayer.

Adhikary S, Deredge DJ, Nagarajan A, Forrest LR, Wintrode PL, Singh SK.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):E1786-E1795. doi: 10.1073/pnas.1613293114. Epub 2017 Feb 21.


An Extra Amino Acid Residue in Transmembrane Domain 10 of the γ-Aminobutyric Acid (GABA) Transporter GAT-1 Is Required for Efficient Ion-coupled Transport.

Dayan O, Nagarajan A, Shah R, Ben-Yona A, Forrest LR, Kanner BI.

J Biol Chem. 2017 Mar 31;292(13):5418-5428. doi: 10.1074/jbc.M117.775189. Epub 2017 Feb 17.


Emulating proton-induced conformational changes in the vesicular monoamine transporter VMAT2 by mutagenesis.

Yaffe D, Vergara-Jaque A, Forrest LR, Schuldiner S.

Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7390-E7398. Epub 2016 Nov 7.


Cation Interactions and Membrane Potential Induce Conformational Changes in NaPi-IIb.

Patti M, Fenollar-Ferrer C, Werner A, Forrest LR, Forster IC.

Biophys J. 2016 Sep 6;111(5):973-88. doi: 10.1016/j.bpj.2016.07.025.


Structure alignment of membrane proteins: Accuracy of available tools and a consensus strategy.

Stamm M, Forrest LR.

Proteins. 2016 Sep;84(9):1333. doi: 10.1002/prot.25098. Epub 2016 Jul 22. No abstract available.


Mechanism of Paroxetine (Paxil) Inhibition of the Serotonin Transporter.

Davis BA, Nagarajan A, Forrest LR, Singh SK.

Sci Rep. 2016 Apr 1;6:23789. doi: 10.1038/srep23789.


The bacterial dicarboxylate transporter VcINDY uses a two-domain elevator-type mechanism.

Mulligan C, Fenollar-Ferrer C, Fitzgerald GA, Vergara-Jaque A, Kaufmann D, Li Y, Forrest LR, Mindell JA.

Nat Struct Mol Biol. 2016 Mar;23(3):256-63. doi: 10.1038/nsmb.3166. Epub 2016 Feb 1.


Two Na+ Sites Control Conformational Change in a Neurotransmitter Transporter Homolog.

Tavoulari S, Margheritis E, Nagarajan A, DeWitt DC, Zhang YW, Rosado E, Ravera S, Rhoades E, Forrest LR, Rudnick G.

J Biol Chem. 2016 Jan 15;291(3):1456-71. doi: 10.1074/jbc.M115.692012. Epub 2015 Nov 18.


Family resemblances: A common fold for some dimeric ion-coupled secondary transporters.

Vergara-Jaque A, Fenollar-Ferrer C, Mulligan C, Mindell JA, Forrest LR.

J Gen Physiol. 2015 Nov;146(5):423-34. doi: 10.1085/jgp.201511481.


Molecular Determinants of Substrate Specificity in Sodium-coupled Glutamate Transporters.

Silverstein N, Ewers D, Forrest LR, Fahlke C, Kanner BI.

J Biol Chem. 2015 Nov 27;290(48):28988-96. doi: 10.1074/jbc.M115.682666. Epub 2015 Oct 16.


Repeat-swap homology modeling of secondary active transporters: updated protocol and prediction of elevator-type mechanisms.

Vergara-Jaque A, Fenollar-Ferrer C, Kaufmann D, Forrest LR.

Front Pharmacol. 2015 Sep 4;6:183. doi: 10.3389/fphar.2015.00183. eCollection 2015.


Role of N-glycosylation in renal betaine transport.

Schweikhard ES, Burckhardt BC, Joos F, Fenollar-Ferrer C, Forrest LR, Kempson SA, Ziegler C.

Biochem J. 2015 Sep 1;470(2):169-79. doi: 10.1042/BJ20131031. Epub 2015 Jun 11.


Structure alignment of membrane proteins: Accuracy of available tools and a consensus strategy.

Stamm M, Forrest LR.

Proteins. 2015 Sep;83(9):1720-32. doi: 10.1002/prot.24857. Epub 2015 Aug 1. Erratum in: Proteins. 2016 Sep;84(9):1333.

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