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Items: 1 to 20 of 104

1.

Error-Prone Replication through UV Lesions by DNA Polymerase θ Protects against Skin Cancers.

Yoon JH, McArthur MJ, Park J, Basu D, Wakamiya M, Prakash L, Prakash S.

Cell. 2019 Feb 4. pii: S0092-8674(19)30056-X. doi: 10.1016/j.cell.2019.01.023. [Epub ahead of print]

PMID:
30773314
2.

Structural basis for polymerase η-promoted resistance to the anticancer nucleoside analog cytarabine.

Rechkoblit O, Choudhury JR, Buku A, Prakash L, Prakash S, Aggarwal AK.

Sci Rep. 2018 Aug 23;8(1):12702. doi: 10.1038/s41598-018-30796-w.

3.

Genetic control of predominantly error-free replication through an acrolein-derived minor-groove DNA adduct.

Yoon JH, Hodge RP, Hackfeld LC, Park J, Roy Choudhury J, Prakash S, Prakash L.

J Biol Chem. 2018 Feb 23;293(8):2949-2958. doi: 10.1074/jbc.RA117.000962. Epub 2018 Jan 12.

PMID:
29330301
4.

Translesion synthesis DNA polymerases promote error-free replication through the minor-groove DNA adduct 3-deaza-3-methyladenine.

Yoon JH, Roy Choudhury J, Park J, Prakash S, Prakash L.

J Biol Chem. 2017 Nov 10;292(45):18682-18688. doi: 10.1074/jbc.M117.808659. Epub 2017 Sep 22.

5.

Mechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-ι.

Jain R, Choudhury JR, Buku A, Johnson RE, Prakash L, Prakash S, Aggarwal AK.

Sci Rep. 2017 Mar 8;7:43904. doi: 10.1038/srep43904.

6.

Structure and mechanism of human PrimPol, a DNA polymerase with primase activity.

Rechkoblit O, Gupta YK, Malik R, Rajashankar KR, Johnson RE, Prakash L, Prakash S, Aggarwal AK.

Sci Adv. 2016 Oct 21;2(10):e1601317. eCollection 2016 Oct.

7.

Human DNA polymerase α in binary complex with a DNA:DNA template-primer.

Coloma J, Johnson RE, Prakash L, Prakash S, Aggarwal AK.

Sci Rep. 2016 Apr 1;6:23784. doi: 10.1038/srep23784.

8.

Response to Burgers et al.

Johnson RE, Klassen R, Prakash L, Prakash S.

Mol Cell. 2016 Feb 18;61(4):494-495. doi: 10.1016/j.molcel.2016.01.018. No abstract available.

9.

Rev1 promotes replication through UV lesions in conjunction with DNA polymerases η, ι, and κ but not DNA polymerase ζ.

Yoon JH, Park J, Conde J, Wakamiya M, Prakash L, Prakash S.

Genes Dev. 2015 Dec 15;29(24):2588-602. doi: 10.1101/gad.272229.115.

10.

Genetic Control of Replication through N1-methyladenine in Human Cells.

Conde J, Yoon JH, Roy Choudhury J, Prakash L, Prakash S.

J Biol Chem. 2015 Dec 11;290(50):29794-800. doi: 10.1074/jbc.M115.693010. Epub 2015 Oct 21.

11.

A Major Role of DNA Polymerase δ in Replication of Both the Leading and Lagging DNA Strands.

Johnson RE, Klassen R, Prakash L, Prakash S.

Mol Cell. 2015 Jul 16;59(2):163-175. doi: 10.1016/j.molcel.2015.05.038. Epub 2015 Jul 2.

12.

Identification of two functional PCNA-binding domains in human DNA polymerase κ.

Yoon JH, Acharya N, Park J, Basu D, Prakash S, Prakash L.

Genes Cells. 2014 Jul;19(7):594-601. doi: 10.1111/gtc.12156. Epub 2014 May 22.

13.

Crystal structure of yeast DNA polymerase ε catalytic domain.

Jain R, Rajashankar KR, Buku A, Johnson RE, Prakash L, Prakash S, Aggarwal AK.

PLoS One. 2014 Apr 14;9(4):e94835. doi: 10.1371/journal.pone.0094835. eCollection 2014.

14.

A role for DNA polymerase θ in promoting replication through oxidative DNA lesion, thymine glycol, in human cells.

Yoon JH, Roy Choudhury J, Park J, Prakash S, Prakash L.

J Biol Chem. 2014 May 9;289(19):13177-85. doi: 10.1074/jbc.M114.556977. Epub 2014 Mar 19.

15.

An iron-sulfur cluster in the polymerase domain of yeast DNA polymerase ε.

Jain R, Vanamee ES, Dzikovski BG, Buku A, Johnson RE, Prakash L, Prakash S, Aggarwal AK.

J Mol Biol. 2014 Jan 23;426(2):301-8. doi: 10.1016/j.jmb.2013.10.015. Epub 2013 Oct 19.

16.

The architecture of yeast DNA polymerase ζ.

Gómez-Llorente Y, Malik R, Jain R, Choudhury JR, Johnson RE, Prakash L, Prakash S, Ubarretxena-Belandia I, Aggarwal AK.

Cell Rep. 2013 Oct 17;5(1):79-86. doi: 10.1016/j.celrep.2013.08.046. Epub 2013 Oct 10.

17.

Genetic control of translesion synthesis on leading and lagging DNA strands in plasmids derived from Epstein-Barr virus in human cells.

Yoon JH, Prakash S, Prakash L.

MBio. 2012 Sep 11;3(5):e00271-12. doi: 10.1128/mBio.00271-12. Print 2012.

18.

Pol31 and Pol32 subunits of yeast DNA polymerase δ are also essential subunits of DNA polymerase ζ.

Johnson RE, Prakash L, Prakash S.

Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12455-60. doi: 10.1073/pnas.1206052109. Epub 2012 Jun 18.

19.

Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy.

Ummat A, Rechkoblit O, Jain R, Roy Choudhury J, Johnson RE, Silverstein TD, Buku A, Lone S, Prakash L, Prakash S, Aggarwal AK.

Nat Struct Mol Biol. 2012 May 6;19(6):628-32. doi: 10.1038/nsmb.2295.

20.

Requirement of Rad18 protein for replication through DNA lesions in mouse and human cells.

Yoon JH, Prakash S, Prakash L.

Proc Natl Acad Sci U S A. 2012 May 15;109(20):7799-804. doi: 10.1073/pnas.1204105109. Epub 2012 Apr 30.

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