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Items: 1 to 20 of 34


Merging organoid and organ-on-a-chip technology to generate complex multi-layer tissue models in a human retina-on-a-chip platform.

Achberger K, Probst C, Haderspeck J, Bolz S, Rogal J, Chuchuy J, Nikolova M, Cora V, Antkowiak L, Haq W, Shen N, Schenke-Layland K, Ueffing M, Liebau S, Loskill P.

Elife. 2019 Aug 27;8. pii: e46188. doi: 10.7554/eLife.46188.


Stem cell based human organ-on-a-chip models for drug discovery and development.

Loskill P, Wu JC.

Adv Drug Deliv Rev. 2019 Feb 1;140:1-2. doi: 10.1016/j.addr.2019.07.004. No abstract available.


Building blocks for a European Organ-on-Chip roadmap.

Mastrangeli M, Millet S, Mummery C, Loskill P, Braeken D, Eberle W, Cipriano M, Fernandez L, Graef M, Gidrol X, Picollet-D'Hahan N, Van Meer B, Ochoa I, Schutte M, Van den Eijnden-van Raaij J.

ALTEX. 2019;36(3):481-492. doi: 10.14573/altex.1905221. No abstract available.


Non-invasive marker-independent high content analysis of a microphysiological human pancreas-on-a-chip model.

Zbinden A, Marzi J, Schlünder K, Probst C, Urbanczyk M, Black S, Brauchle EM, Layland SL, Kraushaar U, Duffy G, Schenke-Layland K, Loskill P.

Matrix Biol. 2019 Jun 22. pii: S0945-053X(19)30149-0. doi: 10.1016/j.matbio.2019.06.008. [Epub ahead of print]


Impact of organ-on-a-chip technology on pharmaceutical R&D costs.

Franzen N, van Harten WH, Retèl VP, Loskill P, van den Eijnden-van Raaij J, IJzerman M.

Drug Discov Today. 2019 Sep;24(9):1720-1724. doi: 10.1016/j.drudis.2019.06.003. Epub 2019 Jun 8.


Dose-Dependent Tissue-Level Characterization of a Medical Atmospheric Pressure Argon Plasma Jet.

Weiss M, Barz J, Ackermann M, Utz R, Ghoul A, Weltmann KD, Stope MB, Wallwiener D, Schenke-Layland K, Oehr C, Brucker S, Loskill P.

ACS Appl Mater Interfaces. 2019 Jun 5;11(22):19841-19853. doi: 10.1021/acsami.9b04803. Epub 2019 May 22.


Engineering Tissues from Induced Pluripotent Stem Cells.

Loskill P, Huebsch N.

Tissue Eng Part A. 2019 May;25(9-10):707-710. doi: 10.1089/ten.TEA.2019.0118. Erratum in: Tissue Eng Part A. 2019 Jul;25(13-14):1065.


User-Friendly and Parallelized Generation of Human Induced Pluripotent Stem Cell-Derived Microtissues in a Centrifugal Heart-on-a-Chip.

Schneider O, Zeifang L, Fuchs S, Sailer C, Loskill P.

Tissue Eng Part A. 2019 May;25(9-10):786-798. doi: 10.1089/ten.TEA.2019.0002.


Organ-on-a-chip technologies that can transform ophthalmic drug discovery and disease modeling.

Haderspeck JC, Chuchuy J, Kustermann S, Liebau S, Loskill P.

Expert Opin Drug Discov. 2019 Jan;14(1):47-57. doi: 10.1080/17460441.2019.1551873. Epub 2018 Dec 8.


Stem-cell based organ-on-a-chip models for diabetes research.

Rogal J, Zbinden A, Schenke-Layland K, Loskill P.

Adv Drug Deliv Rev. 2019 Feb 1;140:101-128. doi: 10.1016/j.addr.2018.10.010. Epub 2018 Oct 22. Review.


Electroconductive Biohybrid Collagen/Pristine Graphene Composite Biomaterials with Enhanced Biological Activity.

Ryan AJ, Kearney CJ, Shen N, Khan U, Kelly AG, Probst C, Brauchle E, Biccai S, Garciarena CD, Vega-Mayoral V, Loskill P, Kerrigan SW, Kelly DJ, Schenke-Layland K, Coleman JN, O'Brien FJ.

Adv Mater. 2018 Apr;30(15):e1706442. doi: 10.1002/adma.201706442. Epub 2018 Mar 5.


Organ-on-a-Chip Systems for Women's Health Applications.

Nawroth J, Rogal J, Weiss M, Brucker SY, Loskill P.

Adv Healthc Mater. 2018 Jan;7(2). doi: 10.1002/adhm.201700550. Epub 2017 Oct 6. Review.


Integration concepts for multi-organ chips: how to maintain flexibility?!

Rogal J, Probst C, Loskill P.

Future Sci OA. 2017 Mar 13;3(2):FSO180. doi: 10.4155/fsoa-2016-0092. eCollection 2017 Jun. Review.


WAT-on-a-chip: a physiologically relevant microfluidic system incorporating white adipose tissue.

Loskill P, Sezhian T, Tharp KM, Lee-Montiel FT, Jeeawoody S, Reese WM, Zushin PH, Stahl A, Healy KE.

Lab Chip. 2017 May 2;17(9):1645-1654. doi: 10.1039/c6lc01590e.


Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses.

Huebsch N, Loskill P, Deveshwar N, Spencer CI, Judge LM, Mandegar MA, Fox CB, Mohamed TM, Ma Z, Mathur A, Sheehan AM, Truong A, Saxton M, Yoo J, Srivastava D, Desai TA, So PL, Healy KE, Conklin BR.

Sci Rep. 2016 Apr 20;6:24726. doi: 10.1038/srep24726.


Multivalent hyaluronic acid bioconjugates improve sFlt-1 activity in vitro.

Altiok EI, Santiago-Ortiz JL, Svedlund FL, Zbinden A, Jha AK, Bhatnagar D, Loskill P, Jackson WM, Schaffer DV, Healy KE.

Biomaterials. 2016 Jul;93:95-105. doi: 10.1016/j.biomaterials.2016.03.017. Epub 2016 Mar 12.


A detailed guideline for the fabrication of single bacterial probes used for atomic force spectroscopy.

Thewes N, Loskill P, Spengler C, Hümbert S, Bischoff M, Jacobs K.

Eur Phys J E Soft Matter. 2015 Dec;38(12):140. doi: 10.1140/epje/i2015-15140-2. Epub 2015 Dec 28.


μOrgano: A Lego®-Like Plug & Play System for Modular Multi-Organ-Chips.

Loskill P, Marcus SG, Mathur A, Reese WM, Healy KE.

PLoS One. 2015 Oct 6;10(10):e0139587. doi: 10.1371/journal.pone.0139587. eCollection 2015.


In vitro cardiac tissue models: Current status and future prospects.

Mathur A, Ma Z, Loskill P, Jeeawoody S, Healy KE.

Adv Drug Deliv Rev. 2016 Jan 15;96:203-13. doi: 10.1016/j.addr.2015.09.011. Epub 2015 Sep 30. Review.


Stochastic binding of Staphylococcus aureus to hydrophobic surfaces.

Thewes N, Thewes A, Loskill P, Peisker H, Bischoff M, Herrmann M, Santen L, Jacobs K.

Soft Matter. 2015 Dec 14;11(46):8913-9. doi: 10.1039/c5sm00963d. Epub 2015 Aug 21.


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