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2003 1
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2007 8
2008 4
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Page 1
Structure-Activity Relationship of USP5 Inhibitors.
Mann MK, Zepeda-Velázquez CA, González-Álvarez H, Dong A, Kiyota T, Aman AM, Loppnau P, Li Y, Wilson B, Arrowsmith CH, Al-Awar R, Harding RJ, Schapira M. Mann MK, et al. Among authors: loppnau p. J Med Chem. 2021 Oct 28;64(20):15017-15036. doi: 10.1021/acs.jmedchem.1c00889. Epub 2021 Oct 14. J Med Chem. 2021. PMID: 34648286
A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II.
Liu Y, Iqbal A, Li W, Ni Z, Wang Y, Ramprasad J, Abraham KJ, Zhang M, Zhao DY, Qin S, Loppnau P, Jiang H, Guo X, Brown PJ, Zhen X, Xu G, Mekhail K, Ji X, Bedford MT, Greenblatt JF, Min J. Liu Y, et al. Among authors: loppnau p. Nat Commun. 2022 Sep 16;13(1):5453. doi: 10.1038/s41467-022-33229-5. Nat Commun. 2022. PMID: 36114190 Free PMC article.
Discovery of a chemical probe for PRDM9.
Allali-Hassani A, Szewczyk MM, Ivanochko D, Organ SL, Bok J, Ho JSY, Gay FPH, Li F, Blazer L, Eram MS, Halabelian L, Dilworth D, Luciani GM, Lima-Fernandes E, Wu Q, Loppnau P, Palmer N, Talib SZA, Brown PJ, Schapira M, Kaldis P, O'Hagan RC, Guccione E, Barsyte-Lovejoy D, Arrowsmith CH, Sanders JM, Kattar SD, Bennett DJ, Nicholson B, Vedadi M. Allali-Hassani A, et al. Among authors: loppnau p. Nat Commun. 2019 Dec 17;10(1):5759. doi: 10.1038/s41467-019-13652-x. Nat Commun. 2019. PMID: 31848333 Free PMC article.
Correction to "Structure-Activity Relationship of USP5 Inhibitors".
Mann MK, Zepeda-Velázquez CA, González-Álvarez H, Dong A, Kiyota T, Aman AM, Loppnau P, Li Y, Wilson B, Arrowsmith CH, Al-Awar R, Harding RJ, Schapira M. Mann MK, et al. Among authors: loppnau p. J Med Chem. 2022 Jan 13;65(1):889. doi: 10.1021/acs.jmedchem.1c02118. Epub 2021 Dec 27. J Med Chem. 2022. PMID: 34958585 No abstract available.
Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40.
Alteen MG, Deme JC, Alvarez CP, Loppnau P, Hutchinson A, Seitova A, Chandrasekaran R, Silva Ramos E, Secker C, Alqazzaz M, Wanker EE, Lea SM, Arrowsmith CH, Harding RJ. Alteen MG, et al. Among authors: loppnau p. Structure. 2023 Sep 7;31(9):1121-1131.e6. doi: 10.1016/j.str.2023.06.002. Epub 2023 Jun 29. Structure. 2023. PMID: 37390814
Crystal structure of chromo barrel domain of RBBP1.
Lei M, Feng Y, Zhou M, Yang Y, Loppnau P, Li Y, Yang Y, Liu Y. Lei M, et al. Among authors: loppnau p. Biochem Biophys Res Commun. 2018 Feb 19;496(4):1344-1348. doi: 10.1016/j.bbrc.2018.02.016. Epub 2018 Feb 3. Biochem Biophys Res Commun. 2018. PMID: 29408527
SS148 and WZ16 inhibit the activities of nsp10-nsp16 complexes from all seven human pathogenic coronaviruses.
Li F, Ghiabi P, Hajian T, Klima M, Li ASM, Khalili Yazdi A, Chau I, Loppnau P, Kutera M, Seitova A, Bolotokova A, Hutchinson A, Perveen S, Boura E, Vedadi M. Li F, et al. Among authors: loppnau p. Biochim Biophys Acta Gen Subj. 2023 Apr;1867(4):130319. doi: 10.1016/j.bbagen.2023.130319. Epub 2023 Feb 9. Biochim Biophys Acta Gen Subj. 2023. PMID: 36764586 Free PMC article.
Epitope-specific antibody responses differentiate COVID-19 outcomes and variants of concern.
Voss C, Esmail S, Liu X, Knauer MJ, Ackloo S, Kaneko T, Lowes L, Stogios P, Seitova A, Hutchinson A, Yusifov F, Skarina T, Evdokimova E, Loppnau P, Ghiabi P, Haijan T, Zhong S, Abdoh H, Hedley BD, Bhayana V, Martin CM, Slessarev M, Chin-Yee B, Fraser DD, Chin-Yee I, Li SS. Voss C, et al. Among authors: loppnau p. JCI Insight. 2021 Jul 8;6(13):e148855. doi: 10.1172/jci.insight.148855. JCI Insight. 2021. PMID: 34081630 Free PMC article.
62 results