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Items: 1 to 20 of 59


Immunosuppressive drug withdrawal late after liver transplantation improves the lipid profile and reduces infections.

Duizendstra AA, de Knegt RJ, Betjes MGH, Coenen S, Murad SD, de Man RA, Metselaar HJ, Sprengers D, Litjens NHR, Kwekkeboom J.

Eur J Gastroenterol Hepatol. 2019 May 14. doi: 10.1097/MEG.0000000000001435. [Epub ahead of print]


Effects of bariatric surgery on telomere length and T-cell aging.

Jongbloed F, Meijers RWJ, IJzermans JNM, Klaassen RA, Dollé MET, van den Berg S, Betjes MGH, de Bruin RWF, van der Harst E, Litjens NHR.

Int J Obes (Lond). 2019 Apr 12. doi: 10.1038/s41366-019-0351-y. [Epub ahead of print]


Increased CD16 expression on NK cells is indicative of antibody-dependent cell-mediated cytotoxicity in chronic-active antibody-mediated rejection.

Sablik KA, Litjens NHR, Klepper M, Betjes MGH.

Transpl Immunol. 2019 Jun;54:52-58. doi: 10.1016/j.trim.2019.02.005. Epub 2019 Feb 19.


A comprehensive characterization of aggravated aging-related changes in T lymphocytes and monocytes in end-stage renal disease: the iESRD study.

Chiu YL, Shu KH, Yang FJ, Chou TY, Chen PM, Lay FY, Pan SY, Lin CJ, Litjens NHR, Betjes MGH, Bermudez S, Kao KC, Chia JS, Wang G, Peng YS, Chuang YF.

Immun Ageing. 2018 Nov 8;15:27. doi: 10.1186/s12979-018-0131-x. eCollection 2018.


Potential Beneficial Effects of Cytomegalovirus Infection after Transplantation.

Litjens NHR, van der Wagen L, Kuball J, Kwekkeboom J.

Front Immunol. 2018 Mar 1;9:389. doi: 10.3389/fimmu.2018.00389. eCollection 2018. Review.


End-Stage Renal Disease Causes Skewing in the TCR Vβ-Repertoire Primarily within CD8+ T Cell Subsets.

Huang L, Betjes MGH, Klepper M, Langerak AW, Baan CC, Litjens NHR.

Front Immunol. 2017 Dec 15;8:1826. doi: 10.3389/fimmu.2017.01826. eCollection 2017.


T-Cell Composition of the Lymph Node Is Associated with the Risk for Early Rejection after Renal Transplantation.

Dedeoglu B, Litjens NHR, de Weerd AE, Dor FJ, Klepper M, Reijerkerk D, Baan CC, Betjes MGH.

Front Immunol. 2017 Oct 27;8:1416. doi: 10.3389/fimmu.2017.01416. eCollection 2017.


Co-inhibitory profile and cytotoxicity of CD57+ PD-1- T cells in end-stage renal disease patients.

Kraaijeveld R, de Graav GN, Dieterich M, Litjens NHR, Hesselink DA, Baan CC.

Clin Exp Immunol. 2018 Mar;191(3):363-372. doi: 10.1111/cei.13070. Epub 2017 Nov 9.


Protective Cytomegalovirus (CMV)-Specific T-Cell Immunity Is Frequent in Kidney Transplant Patients without Serum Anti-CMV Antibodies.

Litjens NHR, Huang L, Dedeoglu B, Meijers RWJ, Kwekkeboom J, Betjes MGH.

Front Immunol. 2017 Sep 12;8:1137. doi: 10.3389/fimmu.2017.01137. eCollection 2017.


CD4+ CD28null T cells are not alloreactive unless stimulated by interleukin-15.

Dedeoglu B, Litjens NHR, Klepper M, Kraaijeveld R, Verschoor W, Baan CC, Betjes MGH.

Am J Transplant. 2018 Feb;18(2):341-350. doi: 10.1111/ajt.14480. Epub 2017 Oct 2.


pERK-dependent defective TCR-mediated activation of CD4+ T cells in end-stage renal disease patients.

Huang L, Litjens NHR, Kannegieter NM, Klepper M, Baan CC, Betjes MGH.

Immun Ageing. 2017 Jun 19;14:14. doi: 10.1186/s12979-017-0096-1. eCollection 2017.


Belatacept Does Not Inhibit Follicular T Cell-Dependent B-Cell Differentiation in Kidney Transplantation.

de Graav GN, Hesselink DA, Dieterich M, Kraaijeveld R, Verschoor W, Roelen DL, Litjens NHR, Chong AS, Weimar W, Baan CC.

Front Immunol. 2017 May 31;8:641. doi: 10.3389/fimmu.2017.00641. eCollection 2017.


Pretransplant Numbers of CD16+ Monocytes as a Novel Biomarker to Predict Acute Rejection After Kidney Transplantation: A Pilot Study.

van den Bosch TPP, Hilbrands LB, Kraaijeveld R, Litjens NHR, Rezaee F, Nieboer D, Steyerberg EW, van Gestel JA, Roelen DL, Clahsen-van Groningen MC, Baan CC, Rowshani AT.

Am J Transplant. 2017 Oct;17(10):2659-2667. doi: 10.1111/ajt.14280. Epub 2017 Apr 22.


Lymph node and circulating T cell characteristics are strongly correlated in end-stage renal disease patients, but highly differentiated T cells reside within the circulation.

Dedeoglu B, de Weerd AE, Huang L, Langerak AW, Dor FJ, Klepper M, Verschoor W, Reijerkerk D, Baan CC, Litjens NH, Betjes MG.

Clin Exp Immunol. 2017 May;188(2):299-310. doi: 10.1111/cei.12934. Epub 2017 Feb 28.


Natural regulatory T cells from patients with end-stage renal disease can be used for large-scale generation of highly suppressive alloantigen-specific Tregs.

Litjens NH, Boer K, Zuijderwijk JM, Klepper M, Peeters AM, Verschoor W, Kraaijeveld R, Betjes MG.

Kidney Int. 2017 May;91(5):1203-1213. doi: 10.1016/j.kint.2016.09.043. Epub 2016 Dec 15.


Latency for cytomegalovirus impacts T cell ageing significantly in elderly end-stage renal disease patients.

Huang L, Langerak AW, Baan CC, Litjens NH, Betjes MG.

Clin Exp Immunol. 2016 Nov;186(2):239-248. doi: 10.1111/cei.12846. Epub 2016 Aug 19.


Loss of CD28 on Peripheral T Cells Decreases the Risk for Early Acute Rejection after Kidney Transplantation.

Dedeoglu B, Meijers RW, Klepper M, Hesselink DA, Baan CC, Litjens NH, Betjes MG.

PLoS One. 2016 Mar 7;11(3):e0150826. doi: 10.1371/journal.pone.0150826. eCollection 2016.


Uremia-Associated Premature Aging of T Cells Does Not Predict Infectious Complications After Renal Transplantation.

Dedeoglu B, Meijers RW, Klepper M, Hesselink DA, Baan CC, Litjens NH, Betjes MG.

Am J Transplant. 2016 Aug;16(8):2324-33. doi: 10.1111/ajt.13759. Epub 2016 Mar 14.


End stage renal disease patients have a skewed T cell receptor Vβ repertoire.

Huang L, Langerak AW, Wolvers-Tettero IL, Meijers RW, Baan CC, Litjens NH, Betjes MG.

Immun Ageing. 2015 Dec 14;12:28. doi: 10.1186/s12979-015-0055-7. eCollection 2015.


Primary Cytomegalovirus Infection Significantly Impacts Circulating T Cells in Kidney Transplant Recipients.

Meijers RW, Litjens NH, Hesselink DA, Langerak AW, Baan CC, Betjes MG.

Am J Transplant. 2015 Dec;15(12):3143-56. doi: 10.1111/ajt.13396. Epub 2015 Jul 24.

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