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Items: 1 to 20 of 28

1.

Knock-down of oncohistone H3F3A-G34W counteracts the neoplastic phenotype of giant cell tumor of bone derived stromal cells.

Fellenberg J, Sähr H, Mancarella D, Plass C, Lindroth AM, Westhauser F, Lehner B, Ewerbeck V.

Cancer Lett. 2019 Apr 28;448:61-69. doi: 10.1016/j.canlet.2019.02.001. Epub 2019 Feb 8.

PMID:
30742944
2.

Transcriptome and protein interaction profiling in cancer cells with mutations in histone H3.3.

Lim J, Park JH, Baude A, Fellenberg J, Zustin J, Haller F, Krücken I, Kang HG, Park YJ, Plass C, Lindroth AM.

Sci Data. 2018 Dec 11;5:180283. doi: 10.1038/sdata.2018.283.

3.

Somatic PRDM2 c.4467delA mutations in colorectal cancers control histone methylation and tumor growth.

Pandzic T, Rendo V, Lim J, Larsson C, Larsson J, Stoimenov I, Kundu S, Ali MA, Hellström M, He L, Lindroth AM, Sjöblom T.

Oncotarget. 2017 Oct 9;8(58):98646-98659. doi: 10.18632/oncotarget.21713. eCollection 2017 Nov 17.

4.

Erratum: DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats.

Brocks D, Schmidt CR, Daskalakis M, Jang HS, Shah NM, Li D, Li J, Zhang B, Hou Y, Laudato S, Lipka DB, Schott J, Bierhoff H, Assenov Y, Helf M, Ressnerova A, Islam MS, Lindroth AM, Haas S, Essers M, Imbusch CD, Brors B, Oehme I, Witt O, Lübbert M, Mallm JP, Rippe K, Will R, Weichenhan D, Stoecklin G, Gerhäuser C, Oakes CC, Wang T, Plass C.

Nat Genet. 2017 Oct 27;49(11):1661. doi: 10.1038/ng1117-1661c.

PMID:
29074949
5.

The histone variant H3.3 G34W substitution in giant cell tumor of the bone link chromatin and RNA processing.

Lim J, Park JH, Baude A, Yoo Y, Lee YK, Schmidt CR, Park JB, Fellenberg J, Zustin J, Haller F, Krücken I, Kang HG, Park YJ, Plass C, Lindroth AM.

Sci Rep. 2017 Oct 18;7(1):13459. doi: 10.1038/s41598-017-13887-y.

6.

Diet-induced obesity leads to metabolic dysregulation in offspring via endoplasmic reticulum stress in a sex-specific manner.

Park JH, Yoo Y, Cho M, Lim J, Lindroth AM, Park YJ.

Int J Obes (Lond). 2018 Feb;42(2):244-251. doi: 10.1038/ijo.2017.203. Epub 2017 Aug 16.

PMID:
28811650
7.

Loss of DIP2C in RKO cells stimulates changes in DNA methylation and epithelial-mesenchymal transition.

Larsson C, Ali MA, Pandzic T, Lindroth AM, He L, Sjöblom T.

BMC Cancer. 2017 Jul 17;17(1):487. doi: 10.1186/s12885-017-3472-5.

8.

DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats.

Brocks D, Schmidt CR, Daskalakis M, Jang HS, Shah NM, Li D, Li J, Zhang B, Hou Y, Laudato S, Lipka DB, Schott J, Bierhoff H, Assenov Y, Helf M, Ressnerova A, Islam MS, Lindroth AM, Haas S, Essers M, Imbusch CD, Brors B, Oehme I, Witt O, Lübbert M, Mallm JP, Rippe K, Will R, Weichenhan D, Stoecklin G, Gerhäuser C, Oakes CC, Wang T, Plass C.

Nat Genet. 2017 Jul;49(7):1052-1060. doi: 10.1038/ng.3889. Epub 2017 Jun 12. Erratum in: Nat Genet. 2017 Oct 27;49(11):1661.

9.

TET-mediated hydroxymethylcytosine at the Pparγ locus is required for initiation of adipogenic differentiation.

Yoo Y, Park JH, Weigel C, Liesenfeld DB, Weichenhan D, Plass C, Seo DG, Lindroth AM, Park YJ.

Int J Obes (Lond). 2017 Apr;41(4):652-659. doi: 10.1038/ijo.2017.8. Epub 2017 Feb 21.

PMID:
28100914
10.

Neuroprotective effects of Paeonia Lactiflora extract against cell death of dopaminergic SH-SY5Y cells is mediated by epigenetic modulation.

Lee G, Joo JC, Choi BY, Lindroth AM, Park SJ, Park YJ.

BMC Complement Altern Med. 2016 Jul 12;16:208. doi: 10.1186/s12906-016-1205-y.

11.

PRC2 loss amplifies Ras signaling in cancer.

Baude A, Lindroth AM, Plass C.

Nat Genet. 2014 Nov;46(11):1154-5. doi: 10.1038/ng.3124.

PMID:
25352098
12.

Long noncoding RNA TARID directs demethylation and activation of the tumor suppressor TCF21 via GADD45A.

Arab K, Park YJ, Lindroth AM, Schäfer A, Oakes C, Weichenhan D, Lukanova A, Lundin E, Risch A, Meister M, Dienemann H, Dyckhoff G, Herold-Mende C, Grummt I, Niehrs C, Plass C.

Mol Cell. 2014 Aug 21;55(4):604-14. doi: 10.1016/j.molcel.2014.06.031. Epub 2014 Jul 31.

13.

Recurrent H3.3 alterations in childhood tumors.

Lindroth AM, Plass C.

Nat Genet. 2013 Dec;45(12):1413-4. doi: 10.1038/ng.2832.

PMID:
24270444
14.

Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas.

Bender S, Tang Y, Lindroth AM, Hovestadt V, Jones DT, Kool M, Zapatka M, Northcott PA, Sturm D, Wang W, Radlwimmer B, Højfeldt JW, Truffaux N, Castel D, Schubert S, Ryzhova M, Seker-Cin H, Gronych J, Johann PD, Stark S, Meyer J, Milde T, Schuhmann M, Ebinger M, Monoranu CM, Ponnuswami A, Chen S, Jones C, Witt O, Collins VP, von Deimling A, Jabado N, Puget S, Grill J, Helin K, Korshunov A, Lichter P, Monje M, Plass C, Cho YJ, Pfister SM.

Cancer Cell. 2013 Nov 11;24(5):660-72. doi: 10.1016/j.ccr.2013.10.006. Epub 2013 Oct 31.

15.

Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer.

Plass C, Pfister SM, Lindroth AM, Bogatyrova O, Claus R, Lichter P.

Nat Rev Genet. 2013 Nov;14(11):765-80. doi: 10.1038/nrg3554. Epub 2013 Oct 9. Review.

PMID:
24105274
16.

Epigenetic biomarkers: a step forward for understanding periodontitis.

Lindroth AM, Park YJ.

J Periodontal Implant Sci. 2013 Jun;43(3):111-20. doi: 10.5051/jpis.2013.43.3.111. Epub 2013 Jun 30.

17.

BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1.

Tönjes M, Barbus S, Park YJ, Wang W, Schlotter M, Lindroth AM, Pleier SV, Bai AHC, Karra D, Piro RM, Felsberg J, Addington A, Lemke D, Weibrecht I, Hovestadt V, Rolli CG, Campos B, Turcan S, Sturm D, Witt H, Chan TA, Herold-Mende C, Kemkemer R, König R, Schmidt K, Hull WE, Pfister SM, Jugold M, Hutson SM, Plass C, Okun JG, Reifenberger G, Lichter P, Radlwimmer B.

Nat Med. 2013 Jul;19(7):901-908. doi: 10.1038/nm.3217. Epub 2013 Jun 23.

18.

Alterations in cardiac DNA methylation in human dilated cardiomyopathy.

Haas J, Frese KS, Park YJ, Keller A, Vogel B, Lindroth AM, Weichenhan D, Franke J, Fischer S, Bauer A, Marquart S, Sedaghat-Hamedani F, Kayvanpour E, Köhler D, Wolf NM, Hassel S, Nietsch R, Wieland T, Ehlermann P, Schultz JH, Dösch A, Mereles D, Hardt S, Backs J, Hoheisel JD, Plass C, Katus HA, Meder B.

EMBO Mol Med. 2013 Mar;5(3):413-29. doi: 10.1002/emmm.201201553. Epub 2013 Jan 22.

19.

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.

Sturm D, Witt H, Hovestadt V, Khuong-Quang DA, Jones DT, Konermann C, Pfaff E, Tönjes M, Sill M, Bender S, Kool M, Zapatka M, Becker N, Zucknick M, Hielscher T, Liu XY, Fontebasso AM, Ryzhova M, Albrecht S, Jacob K, Wolter M, Ebinger M, Schuhmann MU, van Meter T, Frühwald MC, Hauch H, Pekrun A, Radlwimmer B, Niehues T, von Komorowski G, Dürken M, Kulozik AE, Madden J, Donson A, Foreman NK, Drissi R, Fouladi M, Scheurlen W, von Deimling A, Monoranu C, Roggendorf W, Herold-Mende C, Unterberg A, Kramm CM, Felsberg J, Hartmann C, Wiestler B, Wick W, Milde T, Witt O, Lindroth AM, Schwartzentruber J, Faury D, Fleming A, Zakrzewska M, Liberski PP, Zakrzewski K, Hauser P, Garami M, Klekner A, Bognar L, Morrissy S, Cavalli F, Taylor MD, van Sluis P, Koster J, Versteeg R, Volckmann R, Mikkelsen T, Aldape K, Reifenberger G, Collins VP, Majewski J, Korshunov A, Lichter P, Plass C, Jabado N, Pfister SM.

Cancer Cell. 2012 Oct 16;22(4):425-37. doi: 10.1016/j.ccr.2012.08.024.

20.

Sequences sufficient for programming imprinted germline DNA methylation defined.

Park YJ, Herman H, Gao Y, Lindroth AM, Hu BY, Murphy PJ, Putnam JR, Soloway PD.

PLoS One. 2012;7(3):e33024. doi: 10.1371/journal.pone.0033024. Epub 2012 Mar 5.

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