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Items: 13

1.

TGFβ Promotes Genomic Instability after Loss of RUNX3.

Krishnan V, Chong YL, Tan TZ, Kulkarni M, Bin Rahmat MB, Tay LS, Sankar H, Jokhun DS, Ganesan A, Chuang LSH, Voon DC, Shivashankar GV, Thiery JP, Ito Y.

Cancer Res. 2018 Jan 1;78(1):88-102. doi: 10.1158/0008-5472.CAN-17-1178. Epub 2017 Oct 26.

PMID:
29074538
2.

Roles of RUNX in Solid Tumors.

Chuang LS, Ito K, Ito Y.

Adv Exp Med Biol. 2017;962:299-320. doi: 10.1007/978-981-10-3233-2_19. Review.

PMID:
28299665
3.

Molecular mechanism and therapeutic implications of selinexor (KPT-330) in liposarcoma.

Garg M, Kanojia D, Mayakonda A, Said JW, Doan NB, Chien W, Ganesan TS, Chuang LS, Venkatachalam N, Baloglu E, Shacham S, Kauffman M, Koeffler HP.

Oncotarget. 2017 Jan 31;8(5):7521-7532. doi: 10.18632/oncotarget.13485.

4.

Aurora kinase and RUNX: Reaching beyond transcription.

Chuang LS, Krishnan V, Ito Y.

Cell Cycle. 2016 Nov 16;15(22):2999-3000. Epub 2016 Aug 5. No abstract available.

5.

Aurora kinase-induced phosphorylation excludes transcription factor RUNX from the chromatin to facilitate proper mitotic progression.

Chuang LS, Khor JM, Lai SK, Garg S, Krishnan V, Koh CG, Lee SH, Ito Y.

Proc Natl Acad Sci U S A. 2016 Jun 7;113(23):6490-5. doi: 10.1073/pnas.1523157113. Epub 2016 May 23.

6.

The RUNX family: developmental regulators in cancer.

Ito Y, Bae SC, Chuang LS.

Nat Rev Cancer. 2015 Feb;15(2):81-95. doi: 10.1038/nrc3877. Epub 2015 Jan 16. Review.

PMID:
25592647
7.

Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma.

Lee YS, Lee JW, Jang JW, Chi XZ, Kim JH, Li YH, Kim MK, Kim DM, Choi BS, Kim EG, Chung JH, Lee OJ, Lee YM, Suh JW, Chuang LS, Ito Y, Bae SC.

Cancer Cell. 2013 Nov 11;24(5):603-16. doi: 10.1016/j.ccr.2013.10.003.

8.

RUNX family: Regulation and diversification of roles through interacting proteins.

Chuang LS, Ito K, Ito Y.

Int J Cancer. 2013 Mar 15;132(6):1260-71. doi: 10.1002/ijc.27964. Epub 2012 Dec 19. Review.

9.

RUNX3 interactome reveals novel centrosomal targeting of RUNX family of transcription factors.

Chuang LS, Lai SK, Murata-Hori M, Yamada A, Li HY, Gunaratne J, Ito Y.

Cell Cycle. 2012 May 15;11(10):1938-47. doi: 10.4161/cc.20278. Epub 2012 May 15.

PMID:
22544322
10.

RUNX3 functions as an oncogene in ovarian cancer.

Lee CW, Chuang LS, Kimura S, Lai SK, Ong CW, Yan B, Salto-Tellez M, Choolani M, Ito Y.

Gynecol Oncol. 2011 Aug;122(2):410-7. doi: 10.1016/j.ygyno.2011.04.044. Epub 2011 May 25.

PMID:
21612813
11.

Loss of Runx3 is a key event in inducing precancerous state of the stomach.

Ito K, Chuang LS, Ito T, Chang TL, Fukamachi H, Salto-Tellez M, Ito Y.

Gastroenterology. 2011 May;140(5):1536-46.e8. doi: 10.1053/j.gastro.2011.01.043. Epub 2011 Jan 27.

PMID:
21277301
12.

RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis.

Ito K, Lim AC, Salto-Tellez M, Motoda L, Osato M, Chuang LS, Lee CW, Voon DC, Koo JK, Wang H, Fukamachi H, Ito Y.

Cancer Cell. 2008 Sep 9;14(3):226-37. doi: 10.1016/j.ccr.2008.08.004. Erratum in: Cancer Cell. 2009 Mar 3;15(3):240.

13.

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