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A-to-I RNA Editing: An Overlooked Source of Cancer Mutations.

Ben-Aroya S, Levanon EY.

Cancer Cell. 2018 May 14;33(5):789-790. doi: 10.1016/j.ccell.2018.04.006.


A-to-I RNA editing - immune protector and transcriptome diversifier.

Eisenberg E, Levanon EY.

Nat Rev Genet. 2018 Apr 24. doi: 10.1038/s41576-018-0006-1. [Epub ahead of print] Review.


Increased RNA Editing May Provide a Source for Autoantigens in Systemic Lupus Erythematosus.

Roth SH, Danan-Gotthold M, Ben-Izhak M, Rechavi G, Cohen CJ, Louzoun Y, Levanon EY.

Cell Rep. 2018 Apr 3;23(1):50-57. doi: 10.1016/j.celrep.2018.03.036.


Decreased A-to-I RNA editing as a source of keratinocytes' dsRNA in psoriasis.

Shallev L, Kopel E, Feiglin A, Leichner GS, Avni D, Sidi Y, Eisenberg E, Barzilai A, Levanon EY, Greenberger S.

RNA. 2018 Jun;24(6):828-840. doi: 10.1261/rna.064659.117. Epub 2018 Mar 28.


ROP: dumpster diving in RNA-sequencing to find the source of 1 trillion reads across diverse adult human tissues.

Mangul S, Yang HT, Strauli N, Gruhl F, Porath HT, Hsieh K, Chen L, Daley T, Christenson S, Wesolowska-Andersen A, Spreafico R, Rios C, Eng C, Smith AD, Hernandez RD, Ophoff RA, Santana JR, Levanon EY, Woodruff PG, Burchard E, Seibold MA, Shifman S, Eskin E, Zaitlen N.

Genome Biol. 2018 Feb 15;19(1):36. doi: 10.1186/s13059-018-1403-7.


Whole-genome sequencing reveals principles of brain retrotransposition in neurodevelopmental disorders.

Jacob-Hirsch J, Eyal E, Knisbacher BA, Roth J, Cesarkas K, Dor C, Farage-Barhom S, Kunik V, Simon AJ, Gal M, Yalon M, Moshitch-Moshkovitz S, Tearle R, Constantini S, Levanon EY, Amariglio N, Rechavi G.

Cell Res. 2018 Feb;28(2):187-203. doi: 10.1038/cr.2018.8. Epub 2018 Jan 12.


Human cancer tissues exhibit reduced A-to-I editing of miRNAs coupled with elevated editing of their targets.

Pinto Y, Buchumenski I, Levanon EY, Eisenberg E.

Nucleic Acids Res. 2018 Jan 9;46(1):71-82. doi: 10.1093/nar/gkx1176.


RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure.

Solomon O, Di Segni A, Cesarkas K, Porath HT, Marcu-Malina V, Mizrahi O, Stern-Ginossar N, Kol N, Farage-Barhom S, Glick-Saar E, Lerenthal Y, Levanon EY, Amariglio N, Unger R, Goldstein I, Eyal E, Rechavi G.

Nat Commun. 2017 Nov 13;8(1):1440. doi: 10.1038/s41467-017-01458-8.


Promoting RNA editing by ADAR attraction.

Danan-Gotthold M, Levanon EY.

Genome Biol. 2017 Oct 23;18(1):196. doi: 10.1186/s13059-017-1343-7.


Integrating networks and comparative genomics reveals retroelement proliferation dynamics in hominid genomes.

Levy O, Knisbacher BA, Levanon EY, Havlin S.

Sci Adv. 2017 Oct 13;3(10):e1701256. doi: 10.1126/sciadv.1701256. eCollection 2017 Oct.


Massive A-to-I RNA editing is common across the Metazoa and correlates with dsRNA abundance.

Porath HT, Knisbacher BA, Eisenberg E, Levanon EY.

Genome Biol. 2017 Oct 2;18(1):185. doi: 10.1186/s13059-017-1315-y.


Dynamic hyper-editing underlies temperature adaptation in Drosophila.

Buchumenski I, Bartok O, Ashwal-Fluss R, Pandey V, Porath HT, Levanon EY, Kadener S.

PLoS Genet. 2017 Jul 26;13(7):e1006931. doi: 10.1371/journal.pgen.1006931. eCollection 2017 Jul.


A-to-I RNA Editing in the Earliest-Diverging Eumetazoan Phyla.

Porath HT, Schaffer AA, Kaniewska P, Alon S, Eisenberg E, Rosenthal J, Levanon EY, Levy O.

Mol Biol Evol. 2017 Aug 1;34(8):1890-1901. doi: 10.1093/molbev/msx125.


Trade-off between Transcriptome Plasticity and Genome Evolution in Cephalopods.

Liscovitch-Brauer N, Alon S, Porath HT, Elstein B, Unger R, Ziv T, Admon A, Levanon EY, Rosenthal JJC, Eisenberg E.

Cell. 2017 Apr 6;169(2):191-202.e11. doi: 10.1016/j.cell.2017.03.025.


Abnormalities in A-to-I RNA editing patterns in CNS injuries correlate with dynamic changes in cell type composition.

Gal-Mark N, Shallev L, Sweetat S, Barak M, Billy Li J, Levanon EY, Eisenberg E, Behar O.

Sci Rep. 2017 Mar 7;7:43421. doi: 10.1038/srep43421.


Control and automation of multilayered integrated microfluidic device fabrication.

Kipper S, Frolov L, Guy O, Pellach M, Glick Y, Malichi A, Knisbacher BA, Barbiro-Michaely E, Avrahami D, Yavets-Chen Y, Levanon EY, Gerber D.

Lab Chip. 2017 Jan 31;17(3):557-566. doi: 10.1039/c6lc01534d.


Extensive RNA editing and splicing increase immune self-representation diversity in medullary thymic epithelial cells.

Danan-Gotthold M, Guyon C, Giraud M, Levanon EY, Abramson J.

Genome Biol. 2016 Oct 24;17(1):219.


Transcriptome, genetic editing, and microRNA divergence substantiate sympatric speciation of blind mole rat, Spalax.

Li K, Wang L, Knisbacher BA, Xu Q, Levanon EY, Wang H, Frenkel-Morgenstern M, Tagore S, Fang X, Bazak L, Buchumenski I, Zhao Y, Lövy M, Li X, Han L, Frenkel Z, Beiles A, Cao YB, Wang ZL, Nevo E.

Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):7584-9. doi: 10.1073/pnas.1607497113. Epub 2016 Jun 23.


Expanding preconception carrier screening for the Jewish population using high throughput microfluidics technology and next generation sequencing.

Gal M, Khermesh K, Barak M, Lin M, Lahat H, Reznik Wolf H, Lin M, Pras E, Levanon EY.

BMC Med Genomics. 2016 May 13;9(1):24. doi: 10.1186/s12920-016-0184-7.


Clustered mutations in hominid genome evolution are consistent with APOBEC3G enzymatic activity.

Pinto Y, Gabay O, Arbiza L, Sams AJ, Keinan A, Levanon EY.

Genome Res. 2016 May;26(5):579-87. doi: 10.1101/gr.199240.115. Epub 2016 Apr 7.

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