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Items: 19


Tau secretion is correlated to an increase of Golgi dynamics.

Mohamed NV, Desjardins A, Leclerc N.

PLoS One. 2017 May 26;12(5):e0178288. doi: 10.1371/journal.pone.0178288. eCollection 2017.


Rab7A regulates tau secretion.

Rodriguez L, Mohamed NV, Desjardins A, Lippé R, Fon EA, Leclerc N.

J Neurochem. 2017 May;141(4):592-605. doi: 10.1111/jnc.13994. Epub 2017 Mar 29.


Tau Accumulation, Altered Phosphorylation, and Missorting Promote Neurodegeneration in Glaucoma.

Chiasseu M, Cueva Vargas JL, Destroismaisons L, Vande Velde C, Leclerc N, Di Polo A.

J Neurosci. 2016 May 25;36(21):5785-98. doi: 10.1523/JNEUROSCI.3986-15.2016.


G3BP1 promotes stress-induced RNA granule interactions to preserve polyadenylated mRNA.

Aulas A, Caron G, Gkogkas CG, Mohamed NV, Destroismaisons L, Sonenberg N, Leclerc N, Parker JA, Vande Velde C.

J Cell Biol. 2015 Apr 13;209(1):73-84. doi: 10.1083/jcb.201408092. Epub 2015 Apr 6.


Starvation and inhibition of lysosomal function increased tau secretion by primary cortical neurons.

Mohamed NV, Plouffe V, Rémillard-Labrosse G, Planel E, Leclerc N.

Sci Rep. 2014 Jul 17;4:5715. doi: 10.1038/srep05715.


Interaction of 14-3-3ζ with microtubule-associated protein tau within Alzheimer's disease neurofibrillary tangles.

Qureshi HY, Li T, MacDonald R, Cho CM, Leclerc N, Paudel HK.

Biochemistry. 2013 Sep 17;52(37):6445-55. doi: 10.1021/bi400442d. Epub 2013 Sep 4.


Spreading of tau pathology in Alzheimer's disease by cell-to-cell transmission.

Mohamed NV, Herrou T, Plouffe V, Piperno N, Leclerc N.

Eur J Neurosci. 2013 Jun;37(12):1939-48. doi: 10.1111/ejn.12229. Review.


The neurobiology of aging and Alzheimer's disease: walking down the same road?

Jannic B, Karl F, Nicole L, Richard R.

Eur J Neurosci. 2013 Jun;37(12):1885-6. doi: 10.1111/ejn.12261. No abstract available.


Interaction of endogenous tau protein with synaptic proteins is regulated by N-methyl-D-aspartate receptor-dependent tau phosphorylation.

Mondragón-Rodríguez S, Trillaud-Doppia E, Dudilot A, Bourgeois C, Lauzon M, Leclerc N, Boehm J.

J Biol Chem. 2012 Sep 14;287(38):32040-53. doi: 10.1074/jbc.M112.401240. Epub 2012 Jul 25.


Hyperphosphorylation and cleavage at D421 enhance tau secretion.

Plouffe V, Mohamed NV, Rivest-McGraw J, Bertrand J, Lauzon M, Leclerc N.

PLoS One. 2012;7(5):e36873. doi: 10.1371/journal.pone.0036873. Epub 2012 May 15.


Taking organelles apart, putting them back together and creating new ones: lessons from the endoplasmic reticulum.

Lavoie C, Roy L, Lanoix J, Taheri M, Young R, Thibault G, Farah CA, Leclerc N, Paiement J.

Prog Histochem Cytochem. 2011 Jun;46(1):1-48. doi: 10.1016/j.proghi.2011.04.001. Epub 2011 May 4. Review.


The formation of tau pathological phospho-epitopes in the axon is prevented by the dephosphorylation of selective sites in primary hippocampal neurons over-expressing human tau.

Bertrand J, Sénéchal P, Zummo-Soucy M, Plouffe V, Leclerc N.

J Neurochem. 2010 Sep 1;114(5):1353-67. doi: 10.1111/j.1471-4159.2010.06855.x. Epub 2010 Jun 10.


Increased association between rough endoplasmic reticulum membranes and mitochondria in transgenic mice that express P301L tau.

Perreault S, Bousquet O, Lauzon M, Paiement J, Leclerc N.

J Neuropathol Exp Neurol. 2009 May;68(5):503-14. doi: 10.1097/NEN.0b013e3181a1fc49.


HMWMAP2: new perspectives on a pathway to dendritic identity.

Farah CA, Leclerc N.

Cell Motil Cytoskeleton. 2008 Jul;65(7):515-27. doi: 10.1002/cm.20284. Review.


Tau interacts with Golgi membranes and mediates their association with microtubules.

Farah CA, Perreault S, Liazoghli D, Desjardins M, Anton A, Lauzon M, Paiement J, Leclerc N.

Cell Motil Cytoskeleton. 2006 Nov;63(11):710-24.


Fragmentation of the Golgi apparatus induced by the overexpression of wild-type and mutant human tau forms in neurons.

Liazoghli D, Perreault S, Micheva KD, Desjardins M, Leclerc N.

Am J Pathol. 2005 May;166(5):1499-514.


Interaction of microtubule-associated protein-2 and p63: a new link between microtubules and rough endoplasmic reticulum membranes in neurons.

Farah CA, Liazoghli D, Perreault S, Desjardins M, Guimont A, Anton A, Lauzon M, Kreibich G, Paiement J, Leclerc N.

J Biol Chem. 2005 Mar 11;280(10):9439-49. Epub 2004 Dec 28.


Characterization of new cell permeable C3-like proteins that inactivate Rho and stimulate neurite outgrowth on inhibitory substrates.

Winton MJ, Dubreuil CI, Lasko D, Leclerc N, McKerracher L.

J Biol Chem. 2002 Sep 6;277(36):32820-9. Epub 2002 Jun 28.


The projection domain of MAP2b regulates microtubule protrusion and process formation in Sf9 cells.

Bélanger D, Farah CA, Nguyen MD, Lauzon M, Cornibert S, Leclerc N.

J Cell Sci. 2002 Apr 1;115(Pt 7):1523-39.

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