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Items: 9

1.

Untangling the brain's neuroinflammatory and neurodegenerative transcriptional responses.

Srinivasan K, Friedman BA, Larson JL, Lauffer BE, Goldstein LD, Appling LL, Borneo J, Poon C, Ho T, Cai F, Steiner P, van der Brug MP, Modrusan Z, Kaminker JS, Hansen DV.

Nat Commun. 2016 Apr 21;7:11295. doi: 10.1038/ncomms11295.

2.

Cognitive Deficits, Changes in Synaptic Function, and Brain Pathology in a Mouse Model of Normal Aging(1,2,3).

Weber M, Wu T, Hanson JE, Alam NM, Solanoy H, Ngu H, Lauffer BE, Lin HH, Dominguez SL, Reeder J, Tom J, Steiner P, Foreman O, Prusky GT, Scearce-Levie K.

eNeuro. 2015 Oct 15;2(5). pii: ENEURO.0047-15.2015. doi: 10.1523/ENEURO.0047-15.2015. eCollection 2015 Sep.

3.

Histone deacetylase (HDAC) inhibitor kinetic rate constants correlate with cellular histone acetylation but not transcription and cell viability.

Lauffer BE, Mintzer R, Fong R, Mukund S, Tam C, Zilberleyb I, Flicke B, Ritscher A, Fedorowicz G, Vallero R, Ortwine DF, Gunzner J, Modrusan Z, Neumann L, Koth CM, Lupardus PJ, Kaminker JS, Heise CE, Steiner P.

J Biol Chem. 2013 Sep 13;288(37):26926-43. doi: 10.1074/jbc.M113.490706. Epub 2013 Jul 29.

4.

Histone deacetylase 2 cell autonomously suppresses excitatory and enhances inhibitory synaptic function in CA1 pyramidal neurons.

Hanson JE, Deng L, Hackos DH, Lo SC, Lauffer BE, Steiner P, Zhou Q.

J Neurosci. 2013 Apr 3;33(14):5924-9. doi: 10.1523/JNEUROSCI.3162-12.2013.

5.

SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors.

Temkin P, Lauffer B, J├Ąger S, Cimermancic P, Krogan NJ, von Zastrow M.

Nat Cell Biol. 2011 Jun;13(6):715-21. doi: 10.1038/ncb2252. Epub 2011 May 22.

6.

Sequence-dependent sorting of recycling proteins by actin-stabilized endosomal microdomains.

Puthenveedu MA, Lauffer B, Temkin P, Vistein R, Carlton P, Thorn K, Taunton J, Weiner OD, Parton RG, von Zastrow M.

Cell. 2010 Nov 24;143(5):761-73. doi: 10.1016/j.cell.2010.10.003.

7.

SNX27 mediates PDZ-directed sorting from endosomes to the plasma membrane.

Lauffer BE, Melero C, Temkin P, Lei C, Hong W, Kortemme T, von Zastrow M.

J Cell Biol. 2010 Aug 23;190(4):565-74. doi: 10.1083/jcb.201004060.

8.

Engineered protein connectivity to actin mimics PDZ-dependent recycling of G protein-coupled receptors but not its regulation by Hrs.

Lauffer BE, Chen S, Melero C, Kortemme T, von Zastrow M, Vargas GA.

J Biol Chem. 2009 Jan 23;284(4):2448-58. doi: 10.1074/jbc.M806370200. Epub 2008 Nov 10.

9.

N-ethylmaleimide-sensitive factor regulates beta2 adrenoceptor trafficking and signaling in cardiomyocytes.

Wang Y, Lauffer B, Von Zastrow M, Kobilka BK, Xiang Y.

Mol Pharmacol. 2007 Aug;72(2):429-39. Epub 2007 May 17.

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