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Items: 20


Leveraging Epigenetics to Enhance the Cellular Response to Chemotherapies and Improve Tumor Immunogenicity.

Tyutyunyk-Massey L, Haqqani SU, Mandava R, Kentiba K, Dammalapati M, Dao N, Haueis J, Gewirtz D, Landry JW.

Adv Cancer Res. 2018;138:1-39. doi: 10.1016/bs.acr.2018.02.001. Epub 2018 Mar 5.


BPTF inhibits NK cell activity and the abundance of natural cytotoxicity receptor co-ligands.

Mayes K, Elsayed Z, Alhazmi A, Waters M, Alkhatib SG, Roberts M, Song C, Peterson K, Chan V, Ailaney N, Malapati P, Blevins T, Lisnić B, Dumur CI, Landry JW.

Oncotarget. 2017 May 12;8(38):64344-64357. doi: 10.18632/oncotarget.17834. eCollection 2017 Sep 8.


Striatal H3K27 Acetylation Linked to Glutamatergic Gene Dysregulation in Human Heroin Abusers Holds Promise as Therapeutic Target.

Egervari G, Landry J, Callens J, Fullard JF, Roussos P, Keller E, Hurd YL.

Biol Psychiatry. 2017 Apr 1;81(7):585-594. doi: 10.1016/j.biopsych.2016.09.015. Epub 2016 Sep 28.


BPTF Depletion Enhances T-cell-Mediated Antitumor Immunity.

Mayes K, Alkhatib SG, Peterson K, Alhazmi A, Song C, Chan V, Blevins T, Roberts M, Dumur CI, Wang XY, Landry JW.

Cancer Res. 2016 Nov 1;76(21):6183-6192. Epub 2016 Sep 20.


Ino80 is essential for proximal-distal axis asymmetry in part by regulating Bmp4 expression.

Qiu Z, Elsayed Z, Peterkin V, Alkatib S, Bennett D, Landry JW.

BMC Biol. 2016 Mar 14;14:18. doi: 10.1186/s12915-016-0238-5.


Functional interactions between NURF and Ctcf regulate gene expression.

Qiu Z, Song C, Malakouti N, Murray D, Hariz A, Zimmerman M, Gygax D, Alhazmi A, Landry JW.

Mol Cell Biol. 2015 Jan;35(1):224-37. doi: 10.1128/MCB.00553-14. Epub 2014 Oct 27.


ATP-dependent chromatin remodeling complexes as novel targets for cancer therapy.

Mayes K, Qiu Z, Alhazmi A, Landry JW.

Adv Cancer Res. 2014;121:183-233. doi: 10.1016/B978-0-12-800249-0.00005-6. Review.


CHD7 expression predicts survival outcomes in patients with resected pancreatic cancer.

Colbert LE, Petrova AV, Fisher SB, Pantazides BG, Madden MZ, Hardy CW, Warren MD, Pan Y, Nagaraju GP, Liu EA, Saka B, Hall WA, Shelton JW, Gandhi K, Pauly R, Kowalski J, Kooby DA, El-Rayes BF, Staley CA 3rd, Adsay NV, Curran WJ Jr, Landry JC, Maithel SK, Yu DS.

Cancer Res. 2014 May 15;74(10):2677-87. doi: 10.1158/0008-5472.CAN-13-1996. Epub 2014 Mar 13.


The nucleosome remodeling factor.

Alkhatib SG, Landry JW.

FEBS Lett. 2011 Oct 20;585(20):3197-207. doi: 10.1016/j.febslet.2011.09.003. Epub 2011 Sep 9. Review.


Chromatin remodeling complex NURF regulates thymocyte maturation.

Landry JW, Banerjee S, Taylor B, Aplan PD, Singer A, Wu C.

Genes Dev. 2011 Feb 1;25(3):275-86. doi: 10.1101/gad.2007311.


Essential role of chromatin remodeling protein Bptf in early mouse embryos and embryonic stem cells.

Landry J, Sharov AA, Piao Y, Sharova LV, Xiao H, Southon E, Matta J, Tessarollo L, Zhang YE, Ko MS, Kuehn MR, Yamaguchi TP, Wu C.

PLoS Genet. 2008 Oct;4(10):e1000241. doi: 10.1371/journal.pgen.1000241. Epub 2008 Oct 31.


A yeast sir2 mutant temperature sensitive for silencing.

Wang CL, Landry J, Sternglanz R.

Genetics. 2008 Dec;180(4):1955-62. doi: 10.1534/genetics.108.094516. Epub 2008 Oct 9.


A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair.

Wu S, Shi Y, Mulligan P, Gay F, Landry J, Liu H, Lu J, Qi HH, Wang W, Nickoloff JA, Wu C, Shi Y.

Nat Struct Mol Biol. 2007 Dec;14(12):1165-72. Epub 2007 Nov 18.


A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling.

Wysocka J, Swigut T, Xiao H, Milne TA, Kwon SY, Landry J, Kauer M, Tackett AJ, Chait BT, Badenhorst P, Wu C, Allis CD.

Nature. 2006 Jul 6;442(7098):86-90. Epub 2006 May 21.


ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex.

Mizuguchi G, Shen X, Landry J, Wu WH, Sen S, Wu C.

Science. 2004 Jan 16;303(5656):343-8. Epub 2003 Nov 26.


Crystal structure of a SIR2 homolog-NAD complex.

Min J, Landry J, Sternglanz R, Xu RM.

Cell. 2001 Apr 20;105(2):269-79.


A novel form of transcriptional silencing by Sum1-1 requires Hst1 and the origin recognition complex.

Sutton A, Heller RC, Landry J, Choy JS, Sirko A, Sternglanz R.

Mol Cell Biol. 2001 May;21(10):3514-22.


Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose.

Tanner KG, Landry J, Sternglanz R, Denu JM.

Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14178-82.


Role of NAD(+) in the deacetylase activity of the SIR2-like proteins.

Landry J, Slama JT, Sternglanz R.

Biochem Biophys Res Commun. 2000 Nov 30;278(3):685-90.


The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases.

Landry J, Sutton A, Tafrov ST, Heller RC, Stebbins J, Pillus L, Sternglanz R.

Proc Natl Acad Sci U S A. 2000 May 23;97(11):5807-11.

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