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Items: 19

1.

Response to the Letter-to-the Editor by Cohen et al. concerning our eNeurologicalSci article, Melamed-Gal, et al. Physicochemical, biological, functional and toxicological characterization of the European follow-on glatiramer acetate product as compared with Copaxone. eNeurologicalSci 2018;12:19-30.https://doi.org/10.1016/j.ensci.2018.05.006.

Melamed-Gal S, Loupe P, Timan B, Weinstein V, Kolitz S, Zhang J, Funt J, Komlosh A, Ashkenazi N, Bar-Ilan O, Konya A, Beriozkin O, Laifenfeld D, Hasson T, Zeskind B, Hayden M, Nock S, Grossman I.

eNeurologicalSci. 2018 Nov 28;13:53-55. doi: 10.1016/j.ensci.2018.11.007. eCollection 2018 Dec. No abstract available.

2.

Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse.

Kusko R, Dreymann J, Ross J, Cha Y, Escalante-Chong R, Garcia-Miralles M, Tan LJ, Burczynski ME, Zeskind B, Laifenfeld D, Pouladi M, Geva M, Grossman I, Hayden MR.

Mol Neurodegener. 2018 May 21;13(1):25. doi: 10.1186/s13024-018-0259-3.

3.

Compositional differences between Copaxone and Glatopa are reflected in altered immunomodulation ex vivo in a mouse model.

Grossman I, Kolitz S, Komlosh A, Zeskind B, Weinstein V, Laifenfeld D, Gilbert A, Bar-Ilan O, Fowler KD, Hasson T, Konya A, Wells-Knecht K, Loupe P, Melamed-Gal S, Molotsky T, Krispin R, Papir G, Sahly Y, Hayden MR.

Ann N Y Acad Sci. 2017 Nov;1407(1):75-89. doi: 10.1111/nyas.13547.

PMID:
29168242
4.

Biobanking in Israel 2016-17; expressed perceptions versus real life enrollment.

Koren G, Beller D, Laifenfeld D, Grossman I, Shalev V.

BMC Med Ethics. 2017 Nov 17;18(1):63. doi: 10.1186/s12910-017-0223-8.

5.

A pharmacogenetic signature of high response to Copaxone in late-phase clinical-trial cohorts of multiple sclerosis.

Ross CJ, Towfic F, Shankar J, Laifenfeld D, Thoma M, Davis M, Weiner B, Kusko R, Zeskind B, Knappertz V, Grossman I, Hayden MR.

Genome Med. 2017 May 31;9(1):50. doi: 10.1186/s13073-017-0436-y.

6.

Laquinimod arrests experimental autoimmune encephalomyelitis by activating the aryl hydrocarbon receptor.

Kaye J, Piryatinsky V, Birnberg T, Hingaly T, Raymond E, Kashi R, Amit-Romach E, Caballero IS, Towfic F, Ator MA, Rubinstein E, Laifenfeld D, Orbach A, Shinar D, Marantz Y, Grossman I, Knappertz V, Hayden MR, Laufer R.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6145-E6152. Epub 2016 Sep 26.

7.

Targeting Tumor Cells with Anti-CD44 Antibody Triggers Macrophage-Mediated Immune Modulatory Effects in a Cancer Xenograft Model.

Maisel D, Birzele F, Voss E, Nopora A, Bader S, Friess T, Goller B, Laifenfeld D, Weigand S, Runza V.

PLoS One. 2016 Jul 27;11(7):e0159716. doi: 10.1371/journal.pone.0159716. eCollection 2016.

8.

Pharmacogenomics strategies to optimize treatments for multiple sclerosis: Insights from clinical research.

Grossman I, Knappertz V, Laifenfeld D, Ross C, Zeskind B, Kolitz S, Ladkani D, Hayardeny L, Loupe P, Laufer R, Hayden M.

Prog Neurobiol. 2017 May;152:114-130. doi: 10.1016/j.pneurobio.2016.02.001. Epub 2016 Mar 4. Review.

PMID:
26952809
9.

Functional effects of the antigen glatiramer acetate are complex and tightly associated with its composition.

Hasson T, Kolitz S, Towfic F, Laifenfeld D, Bakshi S, Beriozkin O, Shacham-Abramson M, Timan B, Fowler KD, Birnberg T, Konya A, Komlosh A, Ladkani D, Hayden MR, Zeskind B, Grossman I.

J Neuroimmunol. 2016 Jan 15;290:84-95. doi: 10.1016/j.jneuroim.2015.11.020. Epub 2015 Nov 24.

10.

Blood-based identification of non-responders to anti-TNF therapy in rheumatoid arthritis.

Thomson TM, Lescarbeau RM, Drubin DA, Laifenfeld D, de Graaf D, Fryburg DA, Littman B, Deehan R, Van Hooser A.

BMC Med Genomics. 2015 Jun 3;8:26. doi: 10.1186/s12920-015-0100-6.

11.

Gene expression studies of a human monocyte cell line identify dissimilarities between differently manufactured glatiramoids.

Kolitz S, Hasson T, Towfic F, Funt JM, Bakshi S, Fowler KD, Laifenfeld D, Grinspan A, Artyomov MN, Birnberg T, Schwartz R, Komlosh A, Hayardeny L, Ladkani D, Hayden MR, Zeskind B, Grossman I.

Sci Rep. 2015 May 22;5:10191. doi: 10.1038/srep10191.

12.

Utilization of causal reasoning of hepatic gene expression in rats to identify molecular pathways of idiosyncratic drug-induced liver injury.

Laifenfeld D, Qiu L, Swiss R, Park J, Macoritto M, Will Y, Younis HS, Lawton M.

Toxicol Sci. 2014 Jan;137(1):234-48. doi: 10.1093/toxsci/kft232. Epub 2013 Oct 17.

PMID:
24136188
13.

Systems diagnostics: anticipating the next generation of diagnostic tests based on mechanistic insight into disease.

Fryburg DA, Song DH, Laifenfeld D, de Graaf D.

Drug Discov Today. 2014 Feb;19(2):108-12. doi: 10.1016/j.drudis.2013.07.006. Epub 2013 Jul 16.

PMID:
23872468
14.

Early patient stratification and predictive biomarkers in drug discovery and development: a case study of ulcerative colitis anti-TNF therapy.

Laifenfeld D, Drubin DA, Catlett NL, Park JS, Van Hooser AA, Frushour BP, de Graaf D, Fryburg DA, Deehan R.

Adv Exp Med Biol. 2012;736:645-53. doi: 10.1007/978-1-4419-7210-1_38.

PMID:
22161357
15.

The role of hypoxia in 2-butoxyethanol-induced hemangiosarcoma.

Laifenfeld D, Gilchrist A, Drubin D, Jorge M, Eddy SF, Frushour BP, Ladd B, Obert LA, Gosink MM, Cook JC, Criswell K, Somps CJ, Koza-Taylor P, Elliston KO, Lawton MP.

Toxicol Sci. 2010 Jan;113(1):254-66. doi: 10.1093/toxsci/kfp213. Epub 2009 Oct 7.

16.

Rab5 mediates an amyloid precursor protein signaling pathway that leads to apoptosis.

Laifenfeld D, Patzek LJ, McPhie DL, Chen Y, Levites Y, Cataldo AM, Neve RL.

J Neurosci. 2007 Jul 4;27(27):7141-53.

17.

Alterations in cell adhesion molecule L1 and functionally related genes in major depression: a postmortem study.

Laifenfeld D, Karry R, Klein E, Ben-Shachar D.

Biol Psychiatry. 2005 Apr 1;57(7):716-25.

PMID:
15820228
18.

Mitochondria, synaptic plasticity, and schizophrenia.

Ben-Shachar D, Laifenfeld D.

Int Rev Neurobiol. 2004;59:273-96. Review.

PMID:
15006492

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