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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2005 1
2006 1
2007 2
2008 4
2009 2
2010 1
2011 6
2012 6
2013 5
2014 5
2015 3
2016 9
2017 6
2018 3
2019 5
2020 9
2021 6
2022 6
2023 5
2024 1

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73 results

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Page 1
A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier Inhibition.
Laghezza A, Cerchia C, Genovese M, Leuci R, Pranzini E, Santi A, Brunetti L, Piemontese L, Tortorella P, Biswas A, Singh RP, Tambe S, Ca S, Pattnaik AK, Jayaprakash V, Paoli P, Lavecchia A, Loiodice F. Laghezza A, et al. J Med Chem. 2023 Mar 9;66(5):3566-3587. doi: 10.1021/acs.jmedchem.2c02093. Epub 2023 Feb 15. J Med Chem. 2023. PMID: 36790935
A Series of Ferulic Acid Amides Reveals Unexpected Peroxiredoxin 1 Inhibitory Activity with in vivo Antidiabetic and Hypolipidemic Effects.
Yasmin S, Cerchia C, Badavath VN, Laghezza A, Dal Piaz F, Mondal SK, Atlı Ö, Baysal M, Vadivelan S, Shankar S, Siddique MUM, Pattnaik AK, Singh RP, Loiodice F, Jayaprakash V, Lavecchia A. Yasmin S, et al. Among authors: laghezza a. ChemMedChem. 2021 Feb 4;16(3):484-498. doi: 10.1002/cmdc.202000564. Epub 2020 Oct 29. ChemMedChem. 2021. PMID: 33030290
A chemoinformatics search for peroxisome proliferator-activated receptors ligands revealed a new pan-agonist able to reduce lipid accumulation and improve insulin sensitivity.
Sblano S, Cerchia C, Laghezza A, Piemontese L, Brunetti L, Leuci R, Gilardi F, Thomas A, Genovese M, Santi A, Tortorella P, Paoli P, Lavecchia A, Loiodice F. Sblano S, et al. Among authors: laghezza a. Eur J Med Chem. 2022 May 5;235:114240. doi: 10.1016/j.ejmech.2022.114240. Epub 2022 Mar 16. Eur J Med Chem. 2022. PMID: 35325635
A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE).
Leuci R, Brunetti L, Laghezza A, Piemontese L, Carrieri A, Pisani L, Tortorella P, Catto M, Loiodice F. Leuci R, et al. Among authors: laghezza a. Molecules. 2022 Jan 31;27(3):958. doi: 10.3390/molecules27030958. Molecules. 2022. PMID: 35164223 Free PMC article.
73 results