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Items: 1 to 20 of 44


Involvement of N-glycan in Multiple Receptor Tyrosine Kinases Targeted by Ling-Zhi-8 for Suppressing HCC413 Tumor Progression.

You RI, Wu WS, Cheng CC, Wu JR, Pan SM, Chen CW, Hu CT.

Cancers (Basel). 2018 Dec 21;11(1). pii: E9. doi: 10.3390/cancers11010009.


Recombinant Expression and Bioactivity Comparison of Four Typical Fungal Immunomodulatory Proteins from Three Main Ganoderma Species.

Qu ZW, Zhou SY, Guan SX, Gao R, Duan ZW, Zhang X, Sun WY, Fan WL, Chen SS, Chen LJ, Lin JW, Ruan YY.

BMC Biotechnol. 2018 Dec 14;18(1):80. doi: 10.1186/s12896-018-0488-0.


Induction of Cbl-dependent epidermal growth factor receptor degradation in Ling Zhi-8 suppressed lung cancer.

Lin TY, Hsu HY, Sun WH, Wu TH, Tsao SM.

Int J Cancer. 2017 Jun 1;140(11):2596-2607. doi: 10.1002/ijc.30649. Epub 2017 Apr 3.


Identification and Characterisation of a Novel Protein FIP-sch3 from Stachybotrys chartarum.

Li S, Zhao L, Xu W, Jiang Z, Kang J, Wang F, Xin F.

PLoS One. 2016 Dec 20;11(12):e0168436. doi: 10.1371/journal.pone.0168436. eCollection 2016.


Characterisation of a New Fungal Immunomodulatory Protein from Tiger Milk mushroom, Lignosus rhinocerotis.

Pushparajah V, Fatima A, Chong CH, Gambule TZ, Chan CJ, Ng ST, Tan CS, Fung SY, Lee SS, Tan NH, Lim RL.

Sci Rep. 2016 Jul 27;6:30010. doi: 10.1038/srep30010.


Ling Zhi-8 reduces lung cancer mobility and metastasis through disruption of focal adhesion and induction of MDM2-mediated Slug degradation.

Lin TY, Hsu HY.

Cancer Lett. 2016 Jun 1;375(2):340-348. doi: 10.1016/j.canlet.2016.03.018. Epub 2016 Mar 15.


Hydrogen peroxide inducible clone-5 mediates reactive oxygen species signaling for hepatocellular carcinoma progression.

Wu JR, Hu CT, You RI, Pan SM, Cheng CC, Lee MC, Wu CC, Chang YJ, Lin SC, Chen CS, Lin TY, Wu WS.

Oncotarget. 2015 Oct 20;6(32):32526-44. doi: 10.18632/oncotarget.5322.


Preclinical trials for prevention of tumor progression of hepatocellular carcinoma by LZ-8 targeting c-Met dependent and independent pathways.

Wu JR, Hu CT, You RI, Ma PL, Pan SM, Lee MC, Wu WS.

PLoS One. 2015 Jan 21;10(1):e0114495. doi: 10.1371/journal.pone.0114495. eCollection 2015.


An Immunomodulatory Protein (Ling Zhi-8) from a Ganoderma lucidum Induced Acceleration of Wound Healing in Rat Liver Tissues after Monopolar Electrosurgery.

Lin HJ, Chang YS, Lin LH, Haung CF, Wu CY, Ou KL.

Evid Based Complement Alternat Med. 2014;2014:916531. doi: 10.1155/2014/916531. Epub 2014 May 5.


Effect of recombinant human bone morphogenetic protein-2 and Ling Zhi-8 on osteogenesis: a comparative study using a rabbit sinus model.

Hsu HA, Wu CY, Chu JS, Lin LH, Lu CA, Ou KL.

J Oral Maxillofac Surg. 2014 Sep;72(9):1703.e1-1703.e10. doi: 10.1016/j.joms.2014.02.037. Epub 2014 Mar 3. Erratum in: J Oral Maxillofac Surg. 2015 Jan;73(1):196.


Reishi Protein LZ-8 Induces FOXP3(+) Treg Expansion via a CD45-Dependent Signaling Pathway and Alleviates Acute Intestinal Inflammation in Mice.

Hsu HY, Kuan YC, Lin TY, Tsao SM, Hsu J, Ma LJ, Sheu F.

Evid Based Complement Alternat Med. 2013;2013:513542. doi: 10.1155/2013/513542. Epub 2013 Jun 24.


Effect of recombinant Ganoderma lucidum immunoregulatory protein on cyclophosphamide-induced leukopenia in mice.

Zhou H, Sun F, Li H, Zhang S, Liu Z, Pei J, Liang C.

Immunopharmacol Immunotoxicol. 2013 Jun;35(3):426-33. doi: 10.3109/08923973.2013.791834. Epub 2013 May 8.


High-level expression, purification and production of the fungal immunomodulatory protein-gts in baculovirus-infected insect larva.

Wu TY, Chen HA, Li FY, Lin CT, Wu CM, Hsieh FC, Tzen JT, Hsieh SK, Ko JL, Jinn TR.

Appl Biochem Biotechnol. 2013 Feb;169(3):976-89. doi: 10.1007/s12010-012-0049-2. Epub 2013 Jan 8.


Biochemical and functional characterization of recombinant fungal immunomodulatory proteins (rFIPs).

Bastiaan-Net S, Chanput W, Hertz A, Zwittink RD, Mes JJ, Wichers HJ.

Int Immunopharmacol. 2013 Jan;15(1):167-75. doi: 10.1016/j.intimp.2012.11.003. Epub 2012 Nov 19.


Recombinant Lz-8 from Ganoderma lucidum induces endoplasmic reticulum stress-mediated autophagic cell death in SGC-7901 human gastric cancer cells.

Liang C, Li H, Zhou H, Zhang S, Liu Z, Zhou Q, Sun F.

Oncol Rep. 2012 Apr;27(4):1079-89. doi: 10.3892/or.2011.1593. Epub 2011 Dec 14.


A novel adjuvant Ling Zhi-8 for cancer DNA vaccines.

Chu CL, Chen DzC, Lin CC.

Hum Vaccin. 2011 Nov;7(11):1161-4. doi: 10.4161/hv.7.11.17753. Epub 2011 Nov 1.


Ling Zhi-8 mediates p53-dependent growth arrest of lung cancer cells proliferation via the ribosomal protein S7-MDM2-p53 pathway.

Wu CT, Lin TY, Hsu HY, Sheu F, Ho CM, Chen EI.

Carcinogenesis. 2011 Dec;32(12):1890-6. doi: 10.1093/carcin/bgr221. Epub 2011 Oct 7.


A novel adjuvant Ling Zhi-8 enhances the efficacy of DNA cancer vaccine by activating dendritic cells.

Lin CC, Yu YL, Shih CC, Liu KJ, Ou KL, Hong LZ, Chen JD, Chu CL.

Cancer Immunol Immunother. 2011 Jul;60(7):1019-27. doi: 10.1007/s00262-011-1016-4. Epub 2011 Apr 17.


[Expression and crystallographic studies of a fungal immunomodulatory protein LZ-8 from a medicinal fungus Ganoderma lucidum].

An M, Gao GF, Qi J, Li F, Liu X.

Sheng Wu Gong Cheng Xue Bao. 2010 Nov;26(11):1563-8. Chinese.


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