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Very Low Abundance Single-Cell Transcript Quantification with 5-Plex ddPCRTM Assays.

Karlin-Neumann G, Zhang B, Litterst C.

Methods Mol Biol. 2018;1768:423-444. doi: 10.1007/978-1-4939-7778-9_24.


MZC Gel Inhibits SHIV-RT and HSV-2 in Macaque Vaginal Mucosa and SHIV-RT in Rectal Mucosa.

Calenda G, Villegas G, Barnable P, Litterst C, Levendosky K, Gettie A, Cooney ML, Blanchard J, Fernández-Romero JA, Zydowsky TM, Teleshova N.

J Acquir Immune Defic Syndr. 2017 Mar 1;74(3):e67-e74. doi: 10.1097/QAI.0000000000001167.


Quantitative telomerase enzyme activity determination using droplet digital PCR with single cell resolution.

Ludlow AT, Robin JD, Sayed M, Litterst CM, Shelton DN, Shay JW, Wright WE.

Nucleic Acids Res. 2014 Jul;42(13):e104. doi: 10.1093/nar/gku439. Epub 2014 May 26.


Multiplexed target detection using DNA-binding dye chemistry in droplet digital PCR.

McDermott GP, Do D, Litterst CM, Maar D, Hindson CM, Steenblock ER, Legler TC, Jouvenot Y, Marrs SH, Bemis A, Shah P, Wong J, Wang S, Sally D, Javier L, Dinio T, Han C, Brackbill TP, Hodges SP, Ling Y, Klitgord N, Carman GJ, Berman JR, Koehler RT, Hiddessen AL, Walse P, Bousse L, Tzonev S, Hefner E, Hindson BJ, Cauly TH 3rd, Hamby K, Patel VP, Regan JF, Wyatt PW, Karlin-Neumann GA, Stumbo DP, Lowe AJ.

Anal Chem. 2013 Dec 3;85(23):11619-27. doi: 10.1021/ac403061n. Epub 2013 Nov 19.


Akt-mediated phosphorylation of argonaute 2 downregulates cleavage and upregulates translational repression of MicroRNA targets.

Horman SR, Janas MM, Litterst C, Wang B, MacRae IJ, Sever MJ, Morrissey DV, Graves P, Luo B, Umesalma S, Qi HH, Miraglia LJ, Novina CD, Orth AP.

Mol Cell. 2013 May 9;50(3):356-67. doi: 10.1016/j.molcel.2013.03.015. Epub 2013 Apr 18.


Interaction of STAT6 with its co-activator SRC-1/NCoA-1 is regulated by dephosphorylation of the latter via PP2A.

Münz T, Litterst CM, Pfitzner E.

Nucleic Acids Res. 2011 Apr;39(8):3255-66. doi: 10.1093/nar/gkq1225. Epub 2010 Dec 8.


Using an automated cell counter to simplify gene expression studies: siRNA knockdown of IL-4 dependent gene expression in Namalwa cells.

McCoy AM, Litterst C, Collins ML, Ugozzoli LA.

J Vis Exp. 2010 Apr 14;(38). pii: 1904. doi: 10.3791/1904.


Peptide EphB2/CTF2 generated by the gamma-secretase processing of EphB2 receptor promotes tyrosine phosphorylation and cell surface localization of N-methyl-D-aspartate receptors.

Xu J, Litterst C, Georgakopoulos A, Zaganas I, Robakis NK.

J Biol Chem. 2009 Oct 2;284(40):27220-8. doi: 10.1074/jbc.M109.048728. Epub 2009 Aug 6.


Ligand binding and calcium influx induce distinct ectodomain/gamma-secretase-processing pathways of EphB2 receptor.

Litterst C, Georgakopoulos A, Shioi J, Ghersi E, Wisniewski T, Wang R, Ludwig A, Robakis NK.

J Biol Chem. 2007 Jun 1;282(22):16155-63. Epub 2007 Apr 10.


FAD mutants unable to increase neurotoxic Abeta 42 suggest that mutation effects on neurodegeneration may be independent of effects on Abeta.

Shioi J, Georgakopoulos A, Mehta P, Kouchi Z, Litterst CM, Baki L, Robakis NK.

J Neurochem. 2007 May;101(3):674-81. Epub 2007 Jan 24.


Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB-induced Src phosphorylation and signaling.

Georgakopoulos A, Litterst C, Ghersi E, Baki L, Xu C, Serban G, Robakis NK.

EMBO J. 2006 Mar 22;25(6):1242-52. Epub 2006 Mar 2.


Cadherins mediate both the association between PS1 and beta-catenin and the effects of PS1 on beta-catenin stability.

Serban G, Kouchi Z, Baki L, Georgakopoulos A, Litterst CM, Shioi J, Robakis NK.

J Biol Chem. 2005 Oct 28;280(43):36007-12. Epub 2005 Aug 26.


Coactivators in gene regulation by STAT5.

Litterst CM, Kliem S, Lodrini M, Pfitzner E.

Vitam Horm. 2005;70:359-86. Review.


The role of STATs in inflammation and inflammatory diseases.

Pfitzner E, Kliem S, Baus D, Litterst CM.

Curr Pharm Des. 2004;10(23):2839-50. Review.


Recommendations for the nonclinical development of topical microbicides for prevention of HIV transmission: an update.

Lard-Whiteford SL, Matecka D, O'Rear JJ, Yuen IS, Litterst C, Reichelderfer P; International Working Group on Microbicides.

J Acquir Immune Defic Syndr. 2004 May 1;36(1):541-52. Review.


Structure of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain.

Razeto A, Ramakrishnan V, Litterst CM, Giller K, Griesinger C, Carlomagno T, Lakomek N, Heimburg T, Lodrini M, Pfitzner E, Becker S.

J Mol Biol. 2004 Feb 13;336(2):319-29.


NCoA-1/SRC-1 is an essential coactivator of STAT5 that binds to the FDL motif in the alpha-helical region of the STAT5 transactivation domain.

Litterst CM, Kliem S, Marilley D, Pfitzner E.

J Biol Chem. 2003 Nov 14;278(46):45340-51. Epub 2003 Sep 3.


An LXXLL motif in the transactivation domain of STAT6 mediates recruitment of NCoA-1/SRC-1.

Litterst CM, Pfitzner E.

J Biol Chem. 2002 Sep 27;277(39):36052-60. Epub 2002 Jul 22.


Transcriptional activation by STAT6 requires the direct interaction with NCoA-1.

Litterst CM, Pfitzner E.

J Biol Chem. 2001 Dec 7;276(49):45713-21.


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