Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2009 1
2015 1
2016 3
2018 2
2021 3
2024 1

Text availability

Article attribute

Article type

Publication date

Search Results

10 results

Results by year

Filters applied: . Clear all
Page 1
LACTB2 renders radioresistance by activating PINK1/Parkin-dependent mitophagy in nasopharyngeal carcinoma.
Chen Q, Zheng W, Zhu L, Liu H, Song Y, Hu S, Bai Y, Pan Y, Zhang J, Guan J, Shao C. Chen Q, et al. Cancer Lett. 2021 Oct 10;518:127-139. doi: 10.1016/j.canlet.2021.07.019. Epub 2021 Jul 13. Cancer Lett. 2021. PMID: 34271102
Meanwhile, LACTB2 levels were elevated in the serum of patients with NPC after radiotherapy. Inhibiting LACTB2 levels and mitophagy can sensitize NPC cells to ionizing radiation. ...
Meanwhile, LACTB2 levels were elevated in the serum of patients with NPC after radiotherapy. Inhibiting LACTB2 levels and mito …
Identification of LACTB2, a metallo-beta-lactamase protein, as a human mitochondrial endoribonuclease.
Levy S, Allerston CK, Liveanu V, Habib MR, Gileadi O, Schuster G. Levy S, et al. Nucleic Acids Res. 2016 Feb 29;44(4):1813-32. doi: 10.1093/nar/gkw050. Epub 2016 Jan 29. Nucleic Acids Res. 2016. PMID: 26826708 Free PMC article.
Recombinant human LACTB2 displayed robust endoribonuclease activity on ssRNA with a preference for cleavage after purine-pyrimidine sequences. ...Furthermore, manipulation of LACTB2 expression resulted in cellular morphological deformation and cell death. ...
Recombinant human LACTB2 displayed robust endoribonuclease activity on ssRNA with a preference for cleavage after purine-pyrimidine s …
Disruption of NCOA2 by recurrent fusion with LACTB2 in colorectal cancer.
Yu J, Wu WK, Liang Q, Zhang N, He J, Li X, Zhang X, Xu L, Chan MT, Ng SS, Sung JJ. Yu J, et al. Oncogene. 2016 Jan 14;35(2):187-95. doi: 10.1038/onc.2015.72. Epub 2015 Mar 30. Oncogene. 2016. PMID: 25823027 Free PMC article.
Enforced expression of wild-type NCOA2 but not the LACTB2-NCOA2 fusion protein impaired the pro-tumorigenic phenotypes of CRC cells, whereas knockdown of endogenous NCOA2 in normal colonocytes had opposite effects. ...Collectively, our data supports that NCOA2 is a novel n …
Enforced expression of wild-type NCOA2 but not the LACTB2-NCOA2 fusion protein impaired the pro-tumorigenic phenotypes of CRC cells, …
Identification of the prognostic value of LACTB2 and its correlation with immune infiltrates in ovarian cancer by integrated bioinformatics analyses.
Cao W, Wang C, Zhang Y, Yang J, Luo X, Zhao Y, Wu M, Cheng S, Wang Y. Cao W, et al. Eur J Med Res. 2024 Mar 12;29(1):166. doi: 10.1186/s40001-024-01762-2. Eur J Med Res. 2024. PMID: 38475882 Free PMC article.
Therefore, we evaluate the prognostic value and the underlying function of LACTB2 in OC. In this study, high expression of LACTB2 was observed in OC compared with normal controls. ...GESA analysis showed that LACTB2 was closely related to immune-related pathw …
Therefore, we evaluate the prognostic value and the underlying function of LACTB2 in OC. In this study, high expression of LACTB2 …
Defining functional variants associated with Alzheimer's disease in the induced immune response.
Harwood JC, Leonenko G, Sims R, Escott-Price V, Williams J, Holmans P. Harwood JC, et al. Brain Commun. 2021 Apr 19;3(2):fcab083. doi: 10.1093/braincomms/fcab083. eCollection 2021. Brain Commun. 2021. PMID: 33959712 Free PMC article.
Our analysis identified two novel candidate genes for Alzheimer's disease risk, LACTB2 and PLIN2/ADRP. LACTB2 replicated in a transcriptome-wide association study using independent expression weights. LACTB2 and PLIN2/ADRP are involved in mitochondrial functi …
Our analysis identified two novel candidate genes for Alzheimer's disease risk, LACTB2 and PLIN2/ADRP. LACTB2 replicated in a …
Identifying a Major QTL Associated with Salinity Tolerance in Nile Tilapia Using QTL-Seq.
Gu XH, Jiang DL, Huang Y, Li BJ, Chen CH, Lin HR, Xia JH. Gu XH, et al. Mar Biotechnol (NY). 2018 Feb;20(1):98-107. doi: 10.1007/s10126-017-9790-4. Epub 2018 Jan 9. Mar Biotechnol (NY). 2018. PMID: 29318417
Expression analysis indicated that at least 10 genes (e.g., LACTB2, KINH, NCOA2, DIP2C, LARP4B, PEX5R, and KCNJ9) near or within the QTL interval were significantly differentially expressed in intestines, brains, or gills under 10, 15, or 20 ppt challenges. ...
Expression analysis indicated that at least 10 genes (e.g., LACTB2, KINH, NCOA2, DIP2C, LARP4B, PEX5R, and KCNJ9) near or within the …
Genome wide association study identifies two loci associated with cadmium in erythrocytes among never-smokers.
Borné Y, Söderholm M, Barregard L, Fagerberg B, Persson M, Melander O, Thévenod F, Hedblad B, Engström G. Borné Y, et al. Hum Mol Genet. 2016 Jun 1;25(11):2342-2348. doi: 10.1093/hmg/ddw083. Epub 2016 Mar 22. Hum Mol Genet. 2016. PMID: 27005419
Thirteen variants were in linkage disequilibrium on chromosome 8q13.3 in the XKR9 and LACTB2 genes. The lead SNP on 8q13.3 was rs12681420 (minor allele G, minor allele frequency [MAF] = 0.46, beta: -0.11, P = 3.48 10(-11)), an intron variant within the XKR9 gene. ...CONCLU …
Thirteen variants were in linkage disequilibrium on chromosome 8q13.3 in the XKR9 and LACTB2 genes. The lead SNP on 8q13.3 was rs1268 …
Deciphering balanced translocations in infertile males by next-generation sequencing to identify candidate genes for spermatogenesis disorders.
Yammine T, Reynaud N, Lejeune H, Diguet F, Rollat-Farnier PA, Labalme A, Plotton I, Farra C, Sanlaville D, Chouery E, Schluth-Bolard C. Yammine T, et al. Mol Hum Reprod. 2021 May 29;27(6):gaab034. doi: 10.1093/molehr/gaab034. Mol Hum Reprod. 2021. PMID: 34009290
All translocation breakpoints were characterized in the three patients. We identified four variants: a position effect on LACTB2 gene in Patient 1, a heterozygous CTDP1 gene disruption in Patient 2, two single-nucleotide variations (SNVs) in DNAH5 gene and a heterozygous 1 …
All translocation breakpoints were characterized in the three patients. We identified four variants: a position effect on LACTB2 gene …
Protein profilings in mouse liver regeneration after partial hepatectomy using iTRAQ technology.
Hsieh HC, Chen YT, Li JM, Chou TY, Chang MF, Huang SC, Tseng TL, Liu CC, Chen SF. Hsieh HC, et al. J Proteome Res. 2009 Feb;8(2):1004-13. doi: 10.1021/pr800696m. J Proteome Res. 2009. PMID: 19099420
There were 270 proteins for which quantitative information was available at all the time points in both biologically duplicate experiments. Among the 270 proteins, Car3, Mif, Adh1, Lactb2, Fabp5, Es31, Acaa1b and LOC100044783 were consistently down-regulated, and Mat1a, Dn …
There were 270 proteins for which quantitative information was available at all the time points in both biologically duplicate experiments. …