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Items: 19

1.

In vitro screen of a small molecule inhibitor drug library identifies multiple compounds that synergize with oncolytic myxoma virus against human brain tumor-initiating cells.

McKenzie BA, Zemp FJ, Pisklakova A, Narendran A, McFadden G, Lun X, Kenchappa RS, Kurz EU, Forsyth PA.

Neuro Oncol. 2015 Aug;17(8):1086-94. doi: 10.1093/neuonc/nou359. Epub 2015 Jan 20.

2.

Structural determinants of the catalytic inhibition of human topoisomerase IIα by salicylate analogs and salicylate-based drugs.

Bau JT, Kurz EU.

Biochem Pharmacol. 2014 Jun 15;89(4):464-76. doi: 10.1016/j.bcp.2014.03.011. Epub 2014 Mar 30.

PMID:
24695359
3.

Salicylate, a catalytic inhibitor of topoisomerase II, inhibits DNA cleavage and is selective for the α isoform.

Bau JT, Kang Z, Austin CA, Kurz EU.

Mol Pharmacol. 2014 Feb;85(2):198-207. doi: 10.1124/mol.113.088963. Epub 2013 Nov 12.

4.

Sodium salicylate is a novel catalytic inhibitor of human DNA topoisomerase II alpha.

Bau JT, Kurz EU.

Biochem Pharmacol. 2011 Feb 1;81(3):345-54. doi: 10.1016/j.bcp.2010.10.009. Epub 2010 Oct 17.

PMID:
20959117
5.

Altered chloride homeostasis removes synaptic inhibitory constraint of the stress axis.

Hewitt SA, Wamsteeker JI, Kurz EU, Bains JS.

Nat Neurosci. 2009 Apr;12(4):438-43. doi: 10.1038/nn.2274. Epub 2009 Mar 1.

PMID:
19252497
6.
7.

DNA damage-induced activation of ATM and ATM-dependent signaling pathways.

Kurz EU, Lees-Miller SP.

DNA Repair (Amst). 2004 Aug-Sep;3(8-9):889-900. Review.

PMID:
15279774
8.

The isoflavonoids genistein and quercetin activate different stress signaling pathways as shown by analysis of site-specific phosphorylation of ATM, p53 and histone H2AX.

Ye R, Goodarzi AA, Kurz EU, Saito S, Higashimoto Y, Lavin MF, Appella E, Anderson CW, Lees-Miller SP.

DNA Repair (Amst). 2004 Mar 4;3(3):235-44.

PMID:
15177039
9.

Cloning and Characterization of the Murine and Rat mrp1 Promoter Regions.

Muredda M, Nunoya K, Burtch-Wright RA, Kurz EU, Cole SP, Deeley RG.

Mol Pharmacol. 2003 Nov;64(5):1259-69.

10.
11.

Catalytic inhibition of human DNA topoisomerase IIalpha by hypericin, a naphthodianthrone from St. John's wort (Hypericum perforatum).

Peebles KA, Baker RK, Kurz EU, Schneider BJ, Kroll DJ.

Biochem Pharmacol. 2001 Oct 15;62(8):1059-70.

PMID:
11597574
12.

Benzene metabolites antagonize etoposide-stabilized cleavable complexes of DNA topoisomerase IIalpha.

Baker RK, Kurz EU, Pyatt DW, Irons RD, Kroll DJ.

Blood. 2001 Aug 1;98(3):830-3.

14.

Modulation of human DNA topoisomerase IIalpha function by interaction with 14-3-3epsilon.

Kurz EU, Leader KB, Kroll DJ, Clark M, Gieseler F.

J Biol Chem. 2000 May 5;275(18):13948-54.

15.
16.

Response of Cultured Maize Cells to (+)-Abscisic Acid, (-)-Abscisic Acid, and Their Metabolites.

Balsevich JJ, Cutler AJ, Lamb N, Friesen LJ, Kurz EU, Perras MR, Abrams SR.

Plant Physiol. 1994 Sep;106(1):135-142.

17.

Localization of a novel multidrug resistance-associated gene in the HT1080/DR4 and H69AR human tumor cell lines.

Slovak ML, Ho JP, Bhardwaj G, Kurz EU, Deeley RG, Cole SP.

Cancer Res. 1993 Jul 15;53(14):3221-5.

18.

Mechanisms of cartilage degradation in inflammatory arthritis: interaction between chondrocytes and immunoglobulin G.

Saura R, Uno K, Satsuma S, Kurz EU, Scudamore RA, Cooke TD.

J Rheumatol. 1993 Feb;20(2):336-43.

PMID:
8474073
19.

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line.

Cole SP, Bhardwaj G, Gerlach JH, Mackie JE, Grant CE, Almquist KC, Stewart AJ, Kurz EU, Duncan AM, Deeley RG.

Science. 1992 Dec 4;258(5088):1650-4. Erratum in: Science. 1993 May 14;260(5110):879.

PMID:
1360704

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