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Items: 1 to 20 of 82

1.

Modeling the impact of preplanned dose titration on delayed response.

Qu Y, Liu Z, Fu H, Sethuraman S, Kulkarni PM.

J Biopharm Stat. 2018 Oct 25:1-19. doi: 10.1080/10543406.2018.1535499. [Epub ahead of print]

PMID:
30359554
2.

Enantiomer-specific positive allosteric modulation of CB1 signaling in autaptic hippocampal neurons.

Mitjavila J, Yin D, Kulkarni PM, Zanato C, Thakur GA, Ross R, Greig I, Mackie K, Straiker A.

Pharmacol Res. 2018 Mar;129:475-481. doi: 10.1016/j.phrs.2017.11.019. Epub 2017 Nov 20.

PMID:
29158048
3.

Positive Allosteric Modulation of Cannabinoid Receptor Type 1 Suppresses Pathological Pain Without Producing Tolerance or Dependence.

Slivicki RA, Xu Z, Kulkarni PM, Pertwee RG, Mackie K, Thakur GA, Hohmann AG.

Biol Psychiatry. 2018 Nov 15;84(10):722-733. doi: 10.1016/j.biopsych.2017.06.032. Epub 2017 Jul 8.

4.

The In Vivo Effects of the CB1-Positive Allosteric Modulator GAT229 on Intraocular Pressure in Ocular Normotensive and Hypertensive Mice.

Cairns EA, Szczesniak AM, Straiker AJ, Kulkarni PM, Pertwee RG, Thakur GA, Baldridge WH, Kelly MEM.

J Ocul Pharmacol Ther. 2017 Oct;33(8):582-590. doi: 10.1089/jop.2017.0037. Epub 2017 Jul 18.

5.

Small molecule inhibitors of PSD95-nNOS protein-protein interactions suppress formalin-evoked Fos protein expression and nociceptive behavior in rats.

Carey LM, Lee WH, Gutierrez T, Kulkarni PM, Thakur GA, Lai YY, Hohmann AG.

Neuroscience. 2017 May 4;349:303-317. doi: 10.1016/j.neuroscience.2017.02.055. Epub 2017 Mar 8.

6.

Enantiospecific Allosteric Modulation of Cannabinoid 1 Receptor.

Laprairie RB, Kulkarni PM, Deschamps JR, Kelly MEM, Janero DR, Cascio MG, Stevenson LA, Pertwee RG, Kenakin TP, Denovan-Wright EM, Thakur GA.

ACS Chem Neurosci. 2017 Jun 21;8(6):1188-1203. doi: 10.1021/acschemneuro.6b00310. Epub 2017 Feb 7.

PMID:
28103441
7.

Binge alcohol alters exercise-driven neuroplasticity.

Barton EA, Lu Y, Megjhani M, Maynard ME, Kulkarni PM, Roysam B, Leasure JL.

Neuroscience. 2017 Feb 20;343:165-173. doi: 10.1016/j.neuroscience.2016.11.041. Epub 2016 Dec 5.

8.

Mapping Cannabinoid 1 Receptor Allosteric Site(s): Critical Molecular Determinant and Signaling Profile of GAT100, a Novel, Potent, and Irreversibly Binding Probe.

Laprairie RB, Kulkarni AR, Kulkarni PM, Hurst DP, Lynch D, Reggio PH, Janero DR, Pertwee RG, Stevenson LA, Kelly ME, Denovan-Wright EM, Thakur GA.

ACS Chem Neurosci. 2016 Jun 15;7(6):776-98. doi: 10.1021/acschemneuro.6b00041. Epub 2016 Apr 25.

9.

Extending the classification approach for comparing two active treatment arms to binary and time-to-event outcomes.

Liu J, Qu Y, Kulkarni PM.

J Biopharm Stat. 2017;27(4):584-594. doi: 10.1080/10543406.2016.1167074. Epub 2016 Mar 24.

PMID:
27010524
10.

Source memory in rats is impaired by an NMDA receptor antagonist but not by PSD95-nNOS protein-protein interaction inhibitors.

Smith AE, Xu Z, Lai YY, Kulkarni PM, Thakur GA, Hohmann AG, Crystal JD.

Behav Brain Res. 2016 May 15;305:23-9. doi: 10.1016/j.bbr.2016.02.021. Epub 2016 Feb 22.

11.

Nonparametric covariate adjustment in estimating hazard ratios.

Jiang H, Kulkarni PM, Wang Y, Mallinckrodt CH.

Pharm Stat. 2016 Jan-Feb;15(1):46-53. doi: 10.1002/pst.1725. Epub 2015 Nov 26.

PMID:
26610282
12.

Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s).

Kulkarni PM, Kulkarni AR, Korde A, Tichkule RB, Laprairie RB, Denovan-Wright EM, Zhou H, Janero DR, Zvonok N, Makriyannis A, Cascio MG, Pertwee RG, Thakur GA.

J Med Chem. 2016 Jan 14;59(1):44-60. doi: 10.1021/acs.jmedchem.5b01303. Epub 2015 Nov 28.

13.

CT-Based Anatomical Evaluation of Pre-Vertebral Structures With Respect to Vertebral Body Using a Clock-Face Analogy.

Sarwahi V, Gecelter RC, Wendolowski SF, Kulkarni PM, Wang D, Amaral TD, Thornhill B.

Spine (Phila Pa 1976). 2015 Dec;40(24):1918-25. doi: 10.1097/BRS.0000000000001100.

PMID:
26261919
14.

Small molecule inhibitors of PSD95-nNOS protein-protein interactions as novel analgesics.

Lee WH, Xu Z, Ashpole NM, Hudmon A, Kulkarni PM, Thakur GA, Lai YY, Hohmann AG.

Neuropharmacology. 2015 Oct;97:464-75. doi: 10.1016/j.neuropharm.2015.05.038. Epub 2015 Jun 10.

15.

To adjust or not to adjust for baseline when analyzing repeated binary responses? The case of complete data when treatment comparison at study end is of interest.

Jiang H, Kulkarni PM, Mallinckrodt CH, Shurzinske L, Molenberghs G, Lipkovich I.

Pharm Stat. 2015 May-Jun;14(3):262-71. doi: 10.1002/pst.1682. Epub 2015 Apr 10.

PMID:
25866149
16.

Quantitative 3-D analysis of GFAP labeled astrocytes from fluorescence confocal images.

Kulkarni PM, Barton E, Savelonas M, Padmanabhan R, Lu Y, Trett K, Shain W, Leasure JL, Roysam B.

J Neurosci Methods. 2015 May 15;246:38-51. doi: 10.1016/j.jneumeth.2015.02.014. Epub 2015 Mar 5.

PMID:
25745860
17.

Algorithms for improved 3-D reconstruction of live mammalian embryo vasculature from optical coherence tomography data.

Kulkarni PM, Rey-Villamizar N, Merouane A, Sudheendran N, Wang S, Garcia M, Larina IV, Roysam B, Larin KV.

Quant Imaging Med Surg. 2015 Feb;5(1):125-35. doi: 10.3978/j.issn.2223-4292.2014.11.33.

18.

Biosimilars: the need, the challenge, the future: the FDA perspective.

Epstein MS, Ehrenpreis ED, Kulkarni PM; FDA-Related Matters Committee of the American College of Gastroenterology.

Am J Gastroenterol. 2014 Dec;109(12):1856-9. doi: 10.1038/ajg.2014.151. Epub 2014 Jun 24.

PMID:
24957160
19.

Minimally Invasive Surgery in Patients With Adolescent Idiopathic Scoliosis: Is it Better than the Standard Approach? A 2-Year Follow-up Study.

Sarwahi V, Horn JJ, Kulkarni PM, Wollowick AL, Lo Y, Gambassi M, Amaral TD.

Clin Spine Surg. 2016 Oct;29(8):331-40. doi: 10.1097/BSD.0000000000000106.

PMID:
24852384
20.

Pedicle screws adjacent to the great vessels or viscera: a study of 2132 pedicle screws in pediatric spine deformity.

Sarwahi V, Suggs W, Wollowick AL, Kulkarni PM, Lo Y, Amaral TD, Thornhill B.

J Spinal Disord Tech. 2014 Apr;27(2):64-9. doi: 10.1097/BSD.0b013e31825bfecd.

PMID:
24658152

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