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J Pediatr. 2010 Mar;156(3):359-65. doi: 10.1016/j.jpeds.2009.09.009. Epub 2009 Nov 2.

A neurobehavioral intervention and assessment program in very low birth weight infants: outcome at 24 months.

Author information

1
Department of Rehabilitation, Academic Medical Center, University of Amsterdam, The Netherlands.

Abstract

OBJECTIVE:

To determine whether the Infant Behavioral Assessment and Intervention Program (IBAIP) improves development and behavior in very low birth weight (VLBW) infants at 24-month corrected age.

STUDY DESIGN:

In a multicenter, randomized, controlled trial 86 infants received postdischarge intervention until 6-month corrected age. The intervention consisted of supporting infants' self-regulation and development, and facilitating sensitive parent-infant interactions; 90 control infants received regular care. At 6 months, positive intervention effects were found. At 24 months, development and behavior were evaluated with the Bayley Scales of Infant Development-II (BSID-II) and the Child Behavior Check List (CBCL).

RESULTS:

Eighty-three intervention and 78 control infants were available for follow-up. After adjustment for differences in perinatal characteristics, an intervention effect of 6.4 points (+/- standard error, 2.4) on the Psychomotor Developmental Index favored the intervention infants. Groups did not differ on the Mental Developmental Index, the Behavioral Rating Scale of the BSID-II, or on the CBCL. Subgroup analyses revealed improved motor as well as improved mental outcomes in intervention infants with bronchopulmonary dysplasia and with combined biological and social risk factors.

CONCLUSIONS:

The IBAIP shows sustained motor improvement in VLBW infants until 2-year corrected age.

PMID:
19880139
DOI:
10.1016/j.jpeds.2009.09.009
[Indexed for MEDLINE]

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