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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1962 1
1991 1
1993 3
1994 2
1995 2
1996 5
1997 3
1998 5
1999 7
2000 7
2001 5
2002 4
2003 5
2004 2
2005 8
2006 9
2007 5
2008 19
2009 8
2010 7
2011 16
2012 15
2013 22
2014 13
2015 17
2016 18
2017 17
2018 11
2019 10
2020 8
2021 15
2022 14
2023 9
2024 4

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277 results

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Page 1
Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling.
Manik MK, Shi Y, Li S, Zaydman MA, Damaraju N, Eastman S, Smith TG, Gu W, Masic V, Mosaiab T, Weagley JS, Hancock SJ, Vasquez E, Hartley-Tassell L, Kargios N, Maruta N, Lim BYJ, Burdett H, Landsberg MJ, Schembri MA, Prokes I, Song L, Grant M, DiAntonio A, Nanson JD, Guo M, Milbrandt J, Ve T, Kobe B. Manik MK, et al. Among authors: kobe b. Science. 2022 Sep 30;377(6614):eadc8969. doi: 10.1126/science.adc8969. Epub 2022 Sep 30. Science. 2022. PMID: 36048923
Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules.
Shi Y, Kerry PS, Nanson JD, Bosanac T, Sasaki Y, Krauss R, Saikot FK, Adams SE, Mosaiab T, Masic V, Mao X, Rose F, Vasquez E, Furrer M, Cunnea K, Brearley A, Gu W, Luo Z, Brillault L, Landsberg MJ, DiAntonio A, Kobe B, Milbrandt J, Hughes RO, Ve T. Shi Y, et al. Among authors: kobe b. Mol Cell. 2022 May 5;82(9):1643-1659.e10. doi: 10.1016/j.molcel.2022.03.007. Epub 2022 Mar 24. Mol Cell. 2022. PMID: 35334231 Free PMC article.
Capsaicin receptor TRPV1 maintains quiescence of hepatic stellate cells in the liver via recruitment of SARM1.
Tao L, Yang G, Sun T, Jie Tao, Zhu C, Yu H, Cheng Y, Yang Z, Xu M, Jiang Y, Zhang W, Wang Z, Ma W, Wu L, Xue D, Wang D, Yang W, Zhao Y, Horsefield S, Kobe B, Zhang Z, Tang Z, Li Q, Zhai Q, Dooley S, Seki E, Liu P, Xu J, Chen H, Liu C. Tao L, et al. Among authors: kobe b. J Hepatol. 2023 Apr;78(4):805-819. doi: 10.1016/j.jhep.2022.12.031. Epub 2023 Jan 18. J Hepatol. 2023. PMID: 36669703
SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration.
Figley MD, Gu W, Nanson JD, Shi Y, Sasaki Y, Cunnea K, Malde AK, Jia X, Luo Z, Saikot FK, Mosaiab T, Masic V, Holt S, Hartley-Tassell L, McGuinness HY, Manik MK, Bosanac T, Landsberg MJ, Kerry PS, Mobli M, Hughes RO, Milbrandt J, Kobe B, DiAntonio A, Ve T. Figley MD, et al. Among authors: kobe b. Neuron. 2021 Apr 7;109(7):1118-1136.e11. doi: 10.1016/j.neuron.2021.02.009. Epub 2021 Mar 2. Neuron. 2021. PMID: 33657413 Free PMC article.
Megahertz serial crystallography.
Wiedorn MO, Oberthür D, Bean R, Schubert R, Werner N, Abbey B, Aepfelbacher M, Adriano L, Allahgholi A, Al-Qudami N, Andreasson J, Aplin S, Awel S, Ayyer K, Bajt S, Barák I, Bari S, Bielecki J, Botha S, Boukhelef D, Brehm W, Brockhauser S, Cheviakov I, Coleman MA, Cruz-Mazo F, Danilevski C, Darmanin C, Doak RB, Domaracky M, Dörner K, Du Y, Fangohr H, Fleckenstein H, Frank M, Fromme P, Gañán-Calvo AM, Gevorkov Y, Giewekemeyer K, Ginn HM, Graafsma H, Graceffa R, Greiffenberg D, Gumprecht L, Göttlicher P, Hajdu J, Hauf S, Heymann M, Holmes S, Horke DA, Hunter MS, Imlau S, Kaukher A, Kim Y, Klyuev A, Knoška J, Kobe B, Kuhn M, Kupitz C, Küpper J, Lahey-Rudolph JM, Laurus T, Le Cong K, Letrun R, Xavier PL, Maia L, Maia FRNC, Mariani V, Messerschmidt M, Metz M, Mezza D, Michelat T, Mills G, Monteiro DCF, Morgan A, Mühlig K, Munke A, Münnich A, Nette J, Nugent KA, Nuguid T, Orville AM, Pandey S, Pena G, Villanueva-Perez P, Poehlsen J, Previtali G, Redecke L, Riekehr WM, Rohde H, Round A, Safenreiter T, Sarrou I, Sato T, Schmidt M, Schmitt B, Schönherr R, Schulz J, Sellberg JA, Seibert MM, Seuring C, Shelby ML, Shoeman RL, Sikorski M, Silenzi A, Stan CA, Shi X, Stern S, Sztuk-Dambie… See abstract for full author list ➔ Wiedorn MO, et al. Among authors: kobe b. Nat Commun. 2018 Oct 2;9(1):4025. doi: 10.1038/s41467-018-06156-7. Nat Commun. 2018. PMID: 30279492 Free PMC article.
Structural Evolution of TIR-Domain Signalosomes.
Nimma S, Gu W, Maruta N, Li Y, Pan M, Saikot FK, Lim BYJ, McGuinness HY, Zaoti ZF, Li S, Desa S, Manik MK, Nanson JD, Kobe B. Nimma S, et al. Among authors: kobe b. Front Immunol. 2021 Nov 17;12:784484. doi: 10.3389/fimmu.2021.784484. eCollection 2021. Front Immunol. 2021. PMID: 34868065 Free PMC article. Review.
Towards the structure of the TIR-domain signalosome.
Nimma S, Ve T, Williams SJ, Kobe B. Nimma S, et al. Among authors: kobe b. Curr Opin Struct Biol. 2017 Apr;43:122-130. doi: 10.1016/j.sbi.2016.12.014. Epub 2017 Jan 13. Curr Opin Struct Biol. 2017. PMID: 28092811 Review.
Turn up the HEAT.
Kobe B, Gleichmann T, Horne J, Jennings IG, Scotney PD, Teh T. Kobe B, et al. Structure. 1999 May;7(5):R91-7. doi: 10.1016/s0969-2126(99)80060-4. Structure. 1999. PMID: 10378263 Free article. Review.
277 results