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Klin Med (Mosk). 2016;94(7):549-53.

Correction of oxidative stress in patients with chronic cerebral ischemia.

[Article in Russian]

Abstract

A pilot study of the effect of the antioxidant drug ethylmethylhydroxypyridine malate on indicators of oxidative stress in patients with chronic cerebral ischemia. At 6 day course administration investigated the antioxidant in these patients significantly accelerates the process of generation of superoxide anion radical, established by lucigenin-depended chemiluminescence that probably regulate a feedback mechanism oxidase systems. This increases the activity of superoxide dismutase, and reduced the concentration of secondary peroxidation product - malondialdehyde, making reasonable use of antioxidants in the treatment of this pathology.

PMID:
30289222
[Indexed for MEDLINE]

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