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Kidney Int. 2016 Sep;90(3):487-92. doi: 10.1016/j.kint.2016.03.042. Epub 2016 Jun 22.

Insights into the epidemiology and management of lupus nephritis from the US rheumatologist's perspective.

Author information

1
Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. Electronic address: phoover@partners.org.
2
Lupus Center, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Abstract

Lupus nephritis is a common and severe manifestation of systemic lupus erythematosus that disproportionately affects nonwhites and those in lower socioeconomic groups. This review discusses recent data on the incidence, prevalence, and outcomes of patients with lupus nephritis with a focus on low-income US Medicaid patients. We also review recent guidelines on diagnosis, treatment, and screening for new onset and relapses of lupus nephritis. Finally, we discuss the management of lupus nephritis from a rheumatologist's perspective, including vigilance for the common adverse events related to disease and treatment, and we review prevention and new treatment strategies.

KEYWORDS:

epidemiology; glomerulonephritis; lupus

PMID:
27344205
PMCID:
PMC5679458
DOI:
10.1016/j.kint.2016.03.042
[Indexed for MEDLINE]
Free PMC Article

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