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Items: 14


The Influenza A Virus Endoribonuclease PA-X Usurps Host mRNA Processing Machinery to Limit Host Gene Expression.

Gaucherand L, Porter BK, Levene RE, Price EL, Schmaling SK, Rycroft CH, Kevorkian Y, McCormick C, Khaperskyy DA, Gaglia MM.

Cell Rep. 2019 Apr 16;27(3):776-792.e7. doi: 10.1016/j.celrep.2019.03.063.


Adaptive Mutations in Influenza A/California/07/2009 Enhance Polymerase Activity and Infectious Virion Production.

Slaine PD, MacRae C, Kleer M, Lamoureux E, McAlpine S, Warhuus M, Comeau AM, McCormick C, Hatchette T, Khaperskyy DA.

Viruses. 2018 May 18;10(5). pii: E272. doi: 10.3390/v10050272.


Stress Granule-Inducing Eukaryotic Translation Initiation Factor 4A Inhibitors Block Influenza A Virus Replication.

Slaine PD, Kleer M, Smith NK, Khaperskyy DA, McCormick C.

Viruses. 2017 Dec 18;9(12). pii: E388. doi: 10.3390/v9120388.


Translation inhibition and stress granules in the antiviral immune response.

McCormick C, Khaperskyy DA.

Nat Rev Immunol. 2017 Oct;17(10):647-660. doi: 10.1038/nri.2017.63. Epub 2017 Jun 26. Review.


Selective Degradation of Host RNA Polymerase II Transcripts by Influenza A Virus PA-X Host Shutoff Protein.

Khaperskyy DA, Schmaling S, Larkins-Ford J, McCormick C, Gaglia MM.

PLoS Pathog. 2016 Feb 5;12(2):e1005427. doi: 10.1371/journal.ppat.1005427. eCollection 2016 Feb.


Timing Is Everything: Coordinated Control of Host Shutoff by Influenza A Virus NS1 and PA-X Proteins.

Khaperskyy DA, McCormick C.

J Virol. 2015 Jul;89(13):6528-31. doi: 10.1128/JVI.00386-15. Epub 2015 Apr 15. Review.


Influenza a virus host shutoff disables antiviral stress-induced translation arrest.

Khaperskyy DA, Emara MM, Johnston BP, Anderson P, Hatchette TF, McCormick C.

PLoS Pathog. 2014 Jul 10;10(7):e1004217. doi: 10.1371/journal.ppat.1004217. eCollection 2014 Jul.


Kaposi's sarcoma-associated herpesvirus G-protein-coupled receptor prevents AU-rich-element-mediated mRNA decay.

Corcoran JA, Khaperskyy DA, Johnston BP, King CA, Cyr DP, Olsthoorn AV, McCormick C.

J Virol. 2012 Aug;86(16):8859-71. doi: 10.1128/JVI.00597-12. Epub 2012 Jun 13.


Influenza A virus inhibits cytoplasmic stress granule formation.

Khaperskyy DA, Hatchette TF, McCormick C.

FASEB J. 2012 Apr;26(4):1629-39. doi: 10.1096/fj.11-196915. Epub 2011 Dec 27.


Assays for monitoring viral manipulation of host ARE-mRNA turnover.

Corcoran JA, Khaperskyy DA, McCormick C.

Methods. 2011 Oct;55(2):172-81. doi: 10.1016/j.ymeth.2011.08.005. Epub 2011 Aug 11.


Functions of Saccharomyces cerevisiae TFIIF during transcription start site utilization.

Khaperskyy DA, Ammerman ML, Majovski RC, Ponticelli AS.

Mol Cell Biol. 2008 Jun;28(11):3757-66. doi: 10.1128/MCB.02272-07. Epub 2008 Mar 24.


A functional role for the switch 2 region of yeast RNA polymerase II in transcription start site utilization and abortive initiation.

Majovski RC, Khaperskyy DA, Ghazy MA, Ponticelli AS.

J Biol Chem. 2005 Oct 14;280(41):34917-23. Epub 2005 Aug 4.


Yeast RNA polymerase II lacking the Rpb9 subunit is impaired for interaction with transcription factor IIF.

Ziegler LM, Khaperskyy DA, Ammerman ML, Ponticelli AS.

J Biol Chem. 2003 Dec 5;278(49):48950-6. Epub 2003 Sep 30.

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