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Items: 1 to 20 of 128

1.

Increased Hyaluronan and TSG-6 in Association with Neuropathologic Changes of Alzheimer's Disease.

Reed MJ, Damodarasamy M, Pathan JL, Chan CK, Spiekerman C, Wight TN, Banks WA, Day AJ, Vernon RB, Keene CD.

J Alzheimers Dis. 2018 Nov 29. doi: 10.3233/JAD-180797. [Epub ahead of print]

PMID:
30507579
2.

Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.

Mukherjee S, Mez J, Trittschuh EH, Saykin AJ, Gibbons LE, Fardo DW, Wessels M, Bauman J, Moore M, Choi SE, Gross AL, Rich J, Louden DKN, Sanders RE, Grabowski TJ, Bird TD, McCurry SM, Snitz BE, Kamboh MI, Lopez OL, De Jager PL, Bennett DA, Keene CD, Larson EB; EPAD Study Group; Investigators from ACT; Investigators from ROS; Investigators from MAP; Investigators from ADNI; Investigators from the University of Pittsburgh ADRC, Crane PK.

Mol Psychiatry. 2018 Dec 4. doi: 10.1038/s41380-018-0298-8. [Epub ahead of print]

PMID:
30514930
3.

A nonhuman primate model of early Alzheimer's disease pathologic change: Implications for disease pathogenesis.

Latimer CS, Shively CA, Keene CD, Jorgensen MJ, Andrews RN, Register TC, Montine TJ, Wilson AM, Neth BJ, Mintz A, Maldjian JA, Whitlow CT, Kaplan JR, Craft S.

Alzheimers Dement. 2018 Nov 19. pii: S1552-5260(18)33246-1. doi: 10.1016/j.jalz.2018.06.3057. [Epub ahead of print]

4.

Mass synaptometry: High-dimensional multi parametric assay for single synapses.

Gajera CR, Fernandez R, Postupna N, Montine KS, Fox EJ, Tebaykin D, Angelo M, Bendall SC, Keene CD, Montine TJ.

J Neurosci Methods. 2018 Nov 20;312:73-83. doi: 10.1016/j.jneumeth.2018.11.008. [Epub ahead of print]

PMID:
30465796
5.

Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease.

Peloso GM, van der Lee SJ; International Genomics of Alzheimer's Project (IGAP), Destefano AL, Seshardi S.

Alzheimers Dement (Amst). 2018 Sep 22;10:595-598. doi: 10.1016/j.dadm.2018.08.008. eCollection 2018.

6.

h-Channels Contribute to Divergent Intrinsic Membrane Properties of Supragranular Pyramidal Neurons in Human versus Mouse Cerebral Cortex.

Kalmbach BE, Buchin A, Long B, Close J, Nandi A, Miller JA, Bakken TE, Hodge RD, Chong P, de Frates R, Dai K, Maltzer Z, Nicovich PR, Keene CD, Silbergeld DL, Gwinn RP, Cobbs C, Ko AL, Ojemann JG, Koch C, Anastassiou CA, Lein ES, Ting JT.

Neuron. 2018 Dec 5;100(5):1194-1208.e5. doi: 10.1016/j.neuron.2018.10.012. Epub 2018 Nov 1.

PMID:
30392798
7.

Modeling Alzheimer's disease in progeria mice. An age-related concept.

Sharma K, Darvas M, Keene CD, Niedernhofer LJ, Ladiges W.

Pathobiol Aging Age Relat Dis. 2018 Oct 4;8(1):1524815. doi: 10.1080/20010001.2018.1524815. eCollection 2018.

8.

Glia-specific APOE epigenetic changes in the Alzheimer's disease brain.

Tulloch J, Leong L, Thomson Z, Chen S, Lee EG, Keene CD, Millard SP, Yu CE.

Brain Res. 2018 Nov 1;1698:179-186. doi: 10.1016/j.brainres.2018.08.006. Epub 2018 Aug 3.

PMID:
30081037
9.

Localized crystal-storing histiocytosis of the posterior fossa.

Flanagan ME, Keene CD, Louis DN, Juric-Sekhar G.

Neuropathology. 2018 Oct;38(5):529-534. doi: 10.1111/neup.12486. Epub 2018 Jul 31.

PMID:
30066398
10.

Exposure to Strong Anticholinergic Medications and Dementia-Related Neuropathology in a Community-Based Autopsy Cohort.

Gray SL, Anderson ML, Hanlon JT, Dublin S, Walker RL, Hubbard RA, Yu O, Montine TJ, Crane PK, Sonnen JA, Keene CD, Larson EB.

J Alzheimers Dis. 2018;65(2):607-616. doi: 10.3233/JAD-171174.

11.

Sex-specific genetic predictors of Alzheimer's disease biomarkers.

Deming Y, Dumitrescu L, Barnes LL, Thambisetty M, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Huentelman M, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, Johnson SC, Albert M, Moghekar A, Del Aguila JL, Fernandez MV, Budde J, Hassenstab J, Fagan AM, Riemenschneider M, Petersen RC, Minthon L, Chao MJ, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Peskind ER, Li G, Davis LK, Sealock JM, Cox NJ; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Alzheimer Disease Genetics Consortium (ADGC), Goate AM, Bennett DA, Schneider JA, Jefferson AL, Cruchaga C, Hohman TJ.

Acta Neuropathol. 2018 Dec;136(6):857-872. doi: 10.1007/s00401-018-1881-4. Epub 2018 Jul 2.

PMID:
29967939
12.

A robust ex vivo experimental platform for molecular-genetic dissection of adult human neocortical cell types and circuits.

Ting JT, Kalmbach B, Chong P, de Frates R, Keene CD, Gwinn RP, Cobbs C, Ko AL, Ojemann JG, Ellenbogen RG, Koch C, Lein E.

Sci Rep. 2018 May 30;8(1):8407. doi: 10.1038/s41598-018-26803-9.

13.

Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau.

Hohman TJ, Dumitrescu L, Barnes LL, Thambisetty M, Beecham G, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, Johnson SC, Albert M, Bennett DA, Schneider JA, Jefferson AL; Alzheimer’s Disease Genetics Consortium and the Alzheimer’s Disease Neuroimaging Initiative.

JAMA Neurol. 2018 Aug 1;75(8):989-998. doi: 10.1001/jamaneurol.2018.0821.

PMID:
29801024
14.

An anatomic transcriptional atlas of human glioblastoma.

Puchalski RB, Shah N, Miller J, Dalley R, Nomura SR, Yoon JG, Smith KA, Lankerovich M, Bertagnolli D, Bickley K, Boe AF, Brouner K, Butler S, Caldejon S, Chapin M, Datta S, Dee N, Desta T, Dolbeare T, Dotson N, Ebbert A, Feng D, Feng X, Fisher M, Gee G, Goldy J, Gourley L, Gregor BW, Gu G, Hejazinia N, Hohmann J, Hothi P, Howard R, Joines K, Kriedberg A, Kuan L, Lau C, Lee F, Lee H, Lemon T, Long F, Mastan N, Mott E, Murthy C, Ngo K, Olson E, Reding M, Riley Z, Rosen D, Sandman D, Shapovalova N, Slaughterbeck CR, Sodt A, Stockdale G, Szafer A, Wakeman W, Wohnoutka PE, White SJ, Marsh D, Rostomily RC, Ng L, Dang C, Jones A, Keogh B, Gittleman HR, Barnholtz-Sloan JS, Cimino PJ, Uppin MS, Keene CD, Farrokhi FR, Lathia JD, Berens ME, Iavarone A, Bernard A, Lein E, Phillips JW, Rostad SW, Cobbs C, Hawrylycz MJ, Foltz GD.

Science. 2018 May 11;360(6389):660-663. doi: 10.1126/science.aaf2666.

PMID:
29748285
15.

APOE DNA methylation is altered in Lewy body dementia.

Tulloch J, Leong L, Chen S, Keene CD, Millard SP, Shutes-David A, Lopez OL, Kofler J, Kaye JA, Woltjer R, Nelson PT, Neltner JH, Jicha GA, Galasko D, Masliah E, Leverenz JB, Yu CE, Tsuang D.

Alzheimers Dement. 2018 Jul;14(7):889-894. doi: 10.1016/j.jalz.2018.02.005. Epub 2018 Mar 12.

PMID:
29544979
16.

Dopamine D1 Receptor-Positive Neurons in the Lateral Nucleus of the Cerebellum Contribute to Cognitive Behavior.

Locke TM, Soden ME, Miller SM, Hunker A, Knakal C, Licholai JA, Dhillon KS, Keene CD, Zweifel LS, Carlson ES.

Biol Psychiatry. 2018 Sep 15;84(6):401-412. doi: 10.1016/j.biopsych.2018.01.019. Epub 2018 Feb 2.

17.

Leptomeninges-Derived Induced Pluripotent Stem Cells and Directly Converted Neurons From Autopsy Cases With Varying Neuropathologic Backgrounds.

Rose SE, Frankowski H, Knupp A, Berry BJ, Martinez R, Dinh SQ, Bruner LT, Willis SL, Crane PK, Larson EB, Grabowski T, Darvas M, Keene CD, Young JE.

J Neuropathol Exp Neurol. 2018 May 1;77(5):353-360. doi: 10.1093/jnen/nly013.

18.

Multimodal Characterization of the Late Effects of Traumatic Brain Injury: A Methodological Overview of the Late Effects of Traumatic Brain Injury Project.

Edlow BL, Keene CD, Perl DP, Iacono D, Folkerth RD, Stewart W, Mac Donald CL, Augustinack J, Diaz-Arrastia R, Estrada C, Flannery E, Gordon WA, Grabowski TJ, Hansen K, Hoffman J, Kroenke C, Larson EB, Lee P, Mareyam A, McNab JA, McPhee J, Moreau AL, Renz A, Richmire K, Stevens A, Tang CY, Tirrell LS, Trittschuh EH, van der Kouwe A, Varjabedian A, Wald LL, Wu O, Yendiki A, Young L, Zöllei L, Fischl B, Crane PK, Dams-O'Connor K.

J Neurotrauma. 2018 Jul 15;35(14):1604-1619. doi: 10.1089/neu.2017.5457. Epub 2018 May 3.

PMID:
29421973
19.

Pathological phosphorylation of tau and TDP-43 by TTBK1 and TTBK2 drives neurodegeneration.

Taylor LM, McMillan PJ, Liachko NF, Strovas TJ, Ghetti B, Bird TD, Keene CD, Kraemer BC.

Mol Neurodegener. 2018 Feb 6;13(1):7. doi: 10.1186/s13024-018-0237-9.

20.

DNA methylation of TOMM40-APOE-APOC2 in Alzheimer's disease.

Shao Y, Shaw M, Todd K, Khrestian M, D'Aleo G, Barnard PJ, Zahratka J, Pillai J, Yu CE, Keene CD, Leverenz JB, Bekris LM.

J Hum Genet. 2018 Apr;63(4):459-471. doi: 10.1038/s10038-017-0393-8. Epub 2018 Jan 25.

PMID:
29371683

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