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Items: 1 to 20 of 64


Ludwig Boltzmann Cluster Oncology (LBC ONC): first 10 years and future perspectives.

Valent P, Hadzijusufovic E, Grunt T, Karlic H, Peter B, Herrmann H, Eisenwort G, Hoermann G, Schulenburg A, Willmann M, Hubmann R, Shehata M, Selzer E, Gleixner KV, Rülicke T, Sperr WR, Marian B, Pfeilstöcker M, Pehamberger H, Keil F, Jäger U, Zielinski C.

Wien Klin Wochenschr. 2018 Sep;130(17-18):517-529. doi: 10.1007/s00508-018-1355-7. Epub 2018 Jul 13. Review.


Statin and Bisphosphonate Induce Starvation in Fast-Growing Cancer Cell Lines.

Karlic H, Haider F, Thaler R, Spitzer S, Klaushofer K, Varga F.

Int J Mol Sci. 2017 Sep 15;18(9). pii: E1982. doi: 10.3390/ijms18091982.


Anabolic and Antiresorptive Modulation of Bone Homeostasis by the Epigenetic Modulator Sulforaphane, a Naturally Occurring Isothiocyanate.

Thaler R, Maurizi A, Roschger P, Sturmlechner I, Khani F, Spitzer S, Rumpler M, Zwerina J, Karlic H, Dudakovic A, Klaushofer K, Teti A, Rucci N, Varga F, van Wijnen AJ.

J Biol Chem. 2016 Mar 25;291(13):6754-71. doi: 10.1074/jbc.M115.678235. Epub 2016 Jan 12.


Inhibition of the mevalonate pathway affects epigenetic regulation in cancer cells.

Karlic H, Thaler R, Gerner C, Grunt T, Proestling K, Haider F, Varga F.

Cancer Genet. 2015 May;208(5):241-52. doi: 10.1016/j.cancergen.2015.03.008. Epub 2015 Mar 18.


The role of epigenetics in the regulation of apoptosis in myelodysplastic syndromes and acute myeloid leukemia.

Karlic H, Herrmann H, Varga F, Thaler R, Reitermaier R, Spitzer S, Ghanim V, Blatt K, Sperr WR, Valent P, Pfeilstöcker M.

Crit Rev Oncol Hematol. 2014 Apr;90(1):1-16. doi: 10.1016/j.critrevonc.2013.10.003. Epub 2013 Oct 12. Review.


Ibandronate increases the expression of the pro-apoptotic gene FAS by epigenetic mechanisms in tumor cells.

Thaler R, Spitzer S, Karlic H, Berger C, Klaushofer K, Varga F.

Biochem Pharmacol. 2013 Jan 15;85(2):173-85. doi: 10.1016/j.bcp.2012.10.016. Epub 2012 Oct 24.


Epigenetics and the power of art.

Karlic H, Baurek P.

Clin Epigenetics. 2011 Aug;2(2):279-82. doi: 10.1007/s13148-011-0033-7. Epub 2011 Apr 15.


Epigenetic mechanisms in anti-cancer actions of bioactive food components--the implications in cancer prevention.

Stefanska B, Karlic H, Varga F, Fabianowska-Majewska K, Haslberger A.

Br J Pharmacol. 2012 Sep;167(2):279-97. doi: 10.1111/j.1476-5381.2012.02002.x. Review.


DMSO is a strong inducer of DNA hydroxymethylation in pre-osteoblastic MC3T3-E1 cells.

Thaler R, Spitzer S, Karlic H, Klaushofer K, Varga F.

Epigenetics. 2012 Jun 1;7(6):635-51. doi: 10.4161/epi.20163. Epub 2012 Jun 1.


5-azacytidine and decitabine exert proapoptotic effects on neoplastic mast cells: role of FAS-demethylation and FAS re-expression, and synergism with FAS-ligand.

Ghanim V, Herrmann H, Heller G, Peter B, Hadzijusufovic E, Blatt K, Schuch K, Cerny-Reiterer S, Mirkina I, Karlic H, Pickl WF, Zöchbauer-Müller S, Valent P.

Blood. 2012 May 3;119(18):4242-52. doi: 10.1182/blood-2011-09-382770. Epub 2012 Mar 21.


Determination of surface concentrations of individual molecule-layers used in nanoscale biosensors by in situ ATR-FTIR spectroscopy.

Punzet M, Baurecht D, Varga F, Karlic H, Heitzinger C.

Nanoscale. 2012 Apr 7;4(7):2431-8. doi: 10.1039/c2nr12038k. Epub 2012 Mar 8.


Blockade of fatty acid synthase induces ubiquitination and degradation of phosphoinositide-3-kinase signaling proteins in ovarian cancer.

Tomek K, Wagner R, Varga F, Singer CF, Karlic H, Grunt TW.

Mol Cancer Res. 2011 Dec;9(12):1767-79. doi: 10.1158/1541-7786.MCR-10-0467. Epub 2011 Oct 4.


Functional aspects of cytidine-guanosine dinucleotides and their locations in genes.

Varga F, Karlic H, Thaler R, Klaushofer K.

Biomol Concepts. 2011 Oct 1;2(5):391-405. doi: 10.1515/BMC.2011.036.


Impact of vitamin D metabolism on clinical epigenetics.

Karlic H, Varga F.

Clin Epigenetics. 2011 Apr;2(1):55-61. doi: 10.1007/s13148-011-0021-y. Epub 2011 Feb 8.


Homocysteine suppresses the expression of the collagen cross-linker lysyl oxidase involving IL-6, Fli1, and epigenetic DNA methylation.

Thaler R, Agsten M, Spitzer S, Paschalis EP, Karlic H, Klaushofer K, Varga F.

J Biol Chem. 2011 Feb 18;286(7):5578-88. doi: 10.1074/jbc.M110.166181. Epub 2010 Dec 9.


Cancer patients' perception of information exchange between hospital-based doctors and their general practitioners.

Spiegel W, Zidek T, Karlic H, Maier M, Vutuc C, Isak K, Micksche M.

J Eval Clin Pract. 2010 Dec;16(6):1309-13. doi: 10.1111/j.1365-2753.2009.01333.x. Epub 2010 Aug 24.


[Tumor stem cell research - basis and challenge for diagnosis and therapy].

Karlic H, Herrmann H, Schulenburg A, Grunt TW, Laffer S, Mirkina I, Hubmann R, Shehata M, Marian B, Selzer E, Pfeilstöcker M, Pittermann E, Jäger U, Pehamberger H, Zielinski C, Valent P.

Wien Klin Wochenschr. 2010 Jul;122(13-14):423-36. doi: 10.1007/s00508-010-1408-z. Epub 2010 Jul 22. Review. German.


Extra-cellular matrix suppresses expression of the apoptosis mediator Fas by epigenetic DNA methylation.

Thaler R, Karlic H, Spitzer S, Klaushofer K, Varga F.

Apoptosis. 2010 Jun;15(6):728-37. doi: 10.1007/s10495-010-0462-3.


Neoplastic stem cells: current concepts and clinical perspectives.

Schulenburg A, Brämswig K, Herrmann H, Karlic H, Mirkina I, Hubmann R, Laffer S, Marian B, Shehata M, Krepler C, Pehamberger H, Grunt T, Jäger U, Zielinski CC, Valent P.

Crit Rev Oncol Hematol. 2010 Nov;76(2):79-98. doi: 10.1016/j.critrevonc.2010.01.001. Epub 2010 Feb 25. Review.


Osteocalcin attenuates T3- and increases vitamin D3-induced expression of MMP-13 in mouse osteoblasts.

Varga F, Rumpler M, Spitzer S, Karlic H, Klaushofer K.

Endocr J. 2009;56(3):441-50. Epub 2009 Feb 18.

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